公开(公告)号：US20150122985A1

公开(公告)日：2015-05-07

申请号：US14483462

申请日：2014-09-11

申请人： Agilent Technologies, Inc.

发明人： Trygve Ristroph ,  Mark Denning ,  Kenneth R. Newton ,  Guthrie Partridge

IPC分类号： H01J49/00 ,  H01J49/26 ,  H01J49/10

CPC分类号： H01J49/0054 ,  H05H1/24 ,  H05H1/2406 ,  H05H2001/4645 ,  H05H2001/481

摘要： An electron capture dissociation (ECD) apparatus includes a plasma source for generating plasma. Analyte ions are exposed to the plasma in an ECD interaction region, either inside or outside the plasma source. The apparatus may include one or more devices for refining the plasma in preparation for interaction with the analyte ions. Refining may entail removing unwanted species from the plasma, such as photons, metastable particles, neutral particles, and/or high-energy electrons unsuitable for ECD, and/or controlling a density of low-energy electrons in the plasma.

摘要翻译： 电子捕获离解（ECD）装置包括用于产生等离子体的等离子体源。 分析物离子在等离子体源的内部或外部的ECD相互作用区域中暴露于等离子体。 该装置可以包括用于精制等离子体以准备与分析物离子相互作用的一个或多个装置。 精炼可能需要从等离子体中除去不需要的物质，例如不适合于ECD的光子，亚稳颗粒，中性粒子和/或高能电子，和/或控制等离子体中低能电子的密度。

公开(公告)号：US20170347443A1

公开(公告)日：2017-11-30

申请号：US15169697

申请日：2016-05-31

申请人： Agilent Technologies, Inc.

发明人： Mark Denning

IPC分类号： H05H3/02

CPC分类号： H05H3/02 ,  H01J27/143 ,  H01J41/12

摘要： An ion throughput pump (ITP) includes a pump inlet configured to communicate with a vacuum chamber; an ionization source fluidly communicating with the vacuum chamber via the pump inlet and configured for ionizing gas species received from the vacuum chamber; a pump outlet; ion optics configured for accelerating ions produced by the ionization source toward the pump outlet; and a roughing pump stage configured for receiving the ions from the ionization source, producing neutral species from the ions, and pumping the neutral species through the pump outlet.

公开(公告)号：US20160254133A1

公开(公告)日：2016-09-01

申请号：US14634745

申请日：2015-02-28

申请人： Agilent Technologies, Inc.

发明人： Viorica Lopez-Avila ,  Mark Denning ,  Mehrnoosh Vahidpour

IPC分类号： H01J49/10 ,  H01J49/04 ,  H01J49/00 ,  H01J49/16 ,  H05H1/46

CPC分类号： H01J49/102 ,  G01N21/714 ,  G01N30/95 ,  H01J27/16 ,  H01J49/0031 ,  H01J49/0409 ,  H01J49/049 ,  H01J49/105 ,  H01J49/161 ,  H05H1/46

摘要： An ion source includes a plasma generator for supplying plasma at an ionization region proximate to a sample surface. The plasma generator applies energy that may be utilized for desorbing analytes from the sample surface as well as for generating plasma by which analytes are excited or ionized. Desorption and ionization/excitation may be controlled as individual modes. The ion source may be interfaced with an ion-based or optical-based spectrometer. A sample support may be provided, which may be capable of performing analytical separation.

摘要翻译： 离子源包括用于在靠近样品表面的电离区域提供等离子体的等离子体发生器。 等离子体发生器施加可用于从样品表面解吸分析物的能量，以及产生分析物被激发或电离的等离子体。 解吸和电离/激发可以作为各种模式来控制。 离子源可以与基于离子或光学的光谱仪接口。 可以提供样品载体，其可以进行分析分离。

公开(公告)号：US09105454B2

公开(公告)日：2015-08-11

申请号：US14483462

申请日：2014-09-11

申请人： Agilent Technologies, Inc.

发明人： Trygve Ristroph ,  Mark Denning ,  Kenneth R. Newton ,  Guthrie Partridge

IPC分类号： H01J49/00 ,  H01J49/10 ,  H01J49/26

CPC分类号： H01J49/0054 ,  H05H1/24 ,  H05H1/2406 ,  H05H2001/4645 ,  H05H2001/481

摘要： An electron capture dissociation (ECD) apparatus includes a plasma source for generating plasma. Analyte ions are exposed to the plasma in an ECD interaction region, either inside or outside the plasma source. The apparatus may include one or more devices for refining the plasma in preparation for interaction with the analyte ions. Refining may entail removing unwanted species from the plasma, such as photons, metastable particles, neutral particles, and/or high-energy electrons unsuitable for ECD, and/or controlling a density of low-energy electrons in the plasma.

摘要翻译： 电子捕获离解（ECD）装置包括用于产生等离子体的等离子体源。 分析离子在等离子体源的内部或外部的ECD相互作用区域中暴露于等离子体。 该装置可以包括用于精制等离子体以准备与分析物离子相互作用的一个或多个装置。 精炼可能需要从等离子体中除去不想要的物质，例如不适合于ECD的光子，亚稳颗粒，中性粒子和/或高能电子，和/或控制等离子体中低能电子的密度。