公开(公告)号：US12220213B2

公开(公告)日：2025-02-11

申请号：US16987851

申请日：2020-08-07

Applicant: Apple Inc.

Inventor： Erno H. Klaassen ,  Wren Nancy Dougherty ,  Richard C. Kimoto ,  Ravi K. Narasimhan ,  Thomas J. Sullivan ,  Stephen J. Waydo ,  Todd K. Whitehurst ,  Santiago Quijano ,  Derek Park-Shing Young ,  Zijing Zeng

IPC: A61B5/021 ,  A61B5/00 ,  A61B5/11 ,  A61B5/1455 ,  G16H20/00 ,  G16H40/67

Abstract: Methods and devices for obtaining a blood pressure measurement of a subject measure a transit time of a blood pulse of the subject. A method includes sensing, with a pulse ejection sensor of a wrist-worn device, ejection of blood from the left ventricle. Arrival of a resulting blood pressure pulse at the wrist is sensed via a pulse arrival sensor of the wrist-worn device. A transit time of the blood pressure pulse from the left ventricle to the wrist is determined. A relative blood pressure value of the subject is determined based on the transit time. A reference absolute blood pressure value associated with the relative blood pressure value is received. An absolute blood pressure value for the relative blood pressure value is determined based on the reference absolute blood pressure value and the relative blood pressure value.

公开(公告)号：US10702171B2

公开(公告)日：2020-07-07

申请号：US15507659

申请日：2015-09-08

Applicant: Apple Inc.

Inventor： Ravi Narasimhan ,  Zijing Zeng ,  Richard C. Kimoto ,  Erno Klaassen ,  Thomas J. Sullivan ,  Derek Park-Shing Young ,  Todd K. Whitehurst

IPC: A61B5/022 ,  A61B5/00 ,  A61B5/021

Abstract: The present invention generally relates to blood pressure monitoring. In some embodiments, methods and devices of measuring a mean arterial pressure are provided and/or monitoring blood pressure changes. A wrist-worn device may include a plurality of sensors backed by a plurality of actuators. Subsets of the plurality of sensors may be selectively actuateable against a wrist of a user using one or more of the plurality of actuators. A preferred sensor and location may be identified based on pressure signals received from each of the sensors. In some embodiments, devices may use a fluid bladder coupled with piezoelectric film sensors. A fluid bladder pressure sensor may be used to calibrate the piezoelectric film signal to provide a static and dynamic pressure reading. In yet another embodiment, a mean arterial pressure may be calculated by processing a swept pressure signal obtained as a sensor is swept through different heights.

公开(公告)号：US20170281024A1

公开(公告)日：2017-10-05

申请号：US15507607

申请日：2015-09-08

Applicant: Apple, Inc.

Inventor： Ravi Narasimhan ,  Richard C. Kimoto ,  Thomas J. Sullivan ,  Todd K. Whitehurst ,  Derek Park-shing Young ,  Zijing Zeng ,  Erno Klaassen

IPC: A61B5/021 ,  A61B5/00

CPC classification number: A61B5/02125 ,  A61B5/024 ,  A61B5/02416 ,  A61B5/11 ,  A61B5/1102 ,  A61B5/681 ,  A61B5/6824

Abstract: Wrist-worn devices and related methods measure a pulse transit time non-invasively and calculate a blood pressure value using the pulse transit time. A wrist-worn device includes an accelerometer, a photo-plethysmogram (PPG) or a pulse pressure sensor, and a controller. The PPG or the pulse pressure sensor coupled to the wrist-worn device for detecting an arrival of a blood pressure pulse at the user's wrist. The controller is configured to process output signals from the accelerometer to detect when the blood pressure pulse is propagated from the left ventricle of the user's heart, process a signal from the PPG or the pulse pressure sensor to detect when the blood pressure pulse arrives at the wrist, calculate a pulse transit time (PTT) for propagation of the blood pressure pulse from the left ventricle to the wrist, and generate one or more blood pressure values for the user based on the PTT.