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11.发明申请Ultrasonic Method And Apparatus For Measuring Intracranial Contents Volume Change 有权用于测量颅内容物体积变化的超声方法和装置公开(公告)号：US20090198137A1
公开(公告)日：2009-08-06
申请号：US12023325
申请日：2008-01-31
IPC分类号： A61B8/08
CPC分类号： A61B8/0808 , A61B8/06 , A61B8/4227 , A61B8/4455
摘要： An ultrasonic method for indicating a characteristic of intracranial components' volume changes includes the transmission of broadband ultrasound from a transmitting transducer positioned on one side of a human head to a receiving transducer located on another side of the human head with decomposition of the received signal into narrowband components and determination therefrom of group delay, phase angle and attenuation as a basis for derivation of the characteristic of the intracranial media.
摘要翻译： 用于指示颅内组分体积变化的特征的超声波方法包括：从位于人头部一侧的发射换能器将宽带超声波传输到位于人头另一侧的接收换能器，将接收到的信号分解为 窄带分量和从其中确定组延迟，相位角和衰减作为推导颅内介质特征的基础。
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12.发明授权Method and apparatus for non-invasively deriving and indicating of dynamic characteristics of the human and animal intracranial media 失效用于非侵入性地导出和指示人和动物颅内媒体的动态特征的方法和装置公开(公告)号：US06387051B1
公开(公告)日：2002-05-14
申请号：US09663313
申请日：2000-09-15
IPC分类号： A61B800
CPC分类号： A61B5/031 , A61B5/4064 , A61B8/0808 , A61B8/4227 , A61B8/463 , A61B8/465
摘要： An ultrasonic method for indicating a characteristic of intraparenchymal brain tissue includes the transmission of broadband ultrasound from a transmitting transducer positioned on one side of a patient's cranium to a receiving transducer located on another side of the cranium with decomposition of the received signal into narrowband components and determination therefrom of group delay, phase angle and attenuation as a basis for derivation of the characteristic of the intraparenchymal tissue within the cranium.
摘要翻译： 用于指示实质内脑组织的特征的超声波方法包括将位于患者颅骨一侧的发射换能器的宽带超声波传输到位于颅骨另一侧的接收换能器，将接收到的信号分解为窄带分量， 确定组延迟，相位角和衰减作为推导颅内实质内组织特征的基础。
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公开(公告)号：US5951477A
公开(公告)日：1999-09-14
申请号：US927613
申请日：1997-09-11
CPC分类号： A61B8/4227 , A61B5/031 , A61B8/06 , A61B8/0808
摘要： An apparatus for measuring the intracranial pressure in a non-invasive manner is described by using an ultrasonic Doppler device which detects the velocities of the blood flow inside the optic artery for both intracranial and extracranium optic artery portions. The eye in which the blood flow is monitored is subjected to a small pressure, sufficient to equalize the blood flow measurements of the internal and external portions of the optic artery. The pressure at which such equalization occurs is found to be an acceptable indication of the intracranial pressure. Various devices are illustrated and used to enable either an automatic or manual intracranial pressure measurement.
摘要翻译： 通过使用检测颅内和颅外动脉部分的视神经内的血流的速度的超声多普勒装置来描述以非侵入性方式测量颅内压的装置。 监测血流的眼睛经受足够小的压力，以平衡视神经内部和外部部分的血流量测量。 发现这种均衡发生的压力被认为是颅内压的可接受的指示。 示出并使用各种装置来实现自动或手动颅内压测量。
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14.发明授权Ultrasonic method and apparatus for measuring intracranial contents volume change 有权用于测量颅内容物体积变化的超声方法和装置公开(公告)号：US07938780B2
公开(公告)日：2011-05-10
申请号：US12023325
申请日：2008-01-31
CPC分类号： A61B8/0808 , A61B8/06 , A61B8/4227 , A61B8/4455
摘要： An ultrasonic method for indicating a characteristic of intracranial components' volume changes includes the transmission of broadband ultrasound from a transmitting transducer positioned on one side of a human head to a receiving transducer located on another side of the human head with decomposition of the received signal into narrowband components and determination therefrom of group delay, phase angle and attenuation as a basis for derivation of the characteristic of the intracranial media.
摘要翻译： 用于指示颅内组分体积变化的特征的超声波方法包括：从位于人头部一侧的发射换能器将宽带超声波传输到位于人头另一侧的接收换能器，将接收到的信号分解为 窄带分量和从其中确定组延迟，相位角和衰减作为推导颅内介质特征的基础。
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公开(公告)号：US20090287084A1
公开(公告)日：2009-11-19
申请号：US12121161
申请日：2008-05-15
IPC分类号： A61B8/14
CPC分类号： A61B8/10 , A61B5/031 , A61B5/6843 , A61B8/06 , A61B8/4209 , A61B8/4227
摘要： A method and apparatus for continuously measuring the absolute intracranial pressure in a non-invasive manner is described by using an ultrasonic Doppler device which detects the pulsatility indexes of the blood flow inside the eye artery for both intracranial and extracranial eye artery portions. The eye in which the blood flow is monitored is subjected to a small pressure, sufficient to equalize the pulsatility index measurements of the internal and external portions of the eye artery. The pressure at which such equalization occurs is used as a reference for autocalibration of the apparatus so that continuous absolute intracranial pressure measurements may be taken over a particular sampling period.
摘要翻译： 通过使用检测颅内和颅外动脉部分的眼动脉内的血流的搏动指数的超声多普勒装置来描述以非侵入性方式连续测量绝对颅内压的方法和装置。 监测血流的眼睛经受足够小的压力，以均衡眼动脉的内部和外部的搏动指数测量值。 将这种均衡发生的压力用作装置的自动校准的参考，使得可以在特定采样周期上进行连续的绝对颅内压测量。
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16.发明申请Apparatus And Method Of Non-Invasive Cerebrovascular Autoregulation Monitoring 有权非侵入性脑血管自动调节监测仪器与方法公开(公告)号：US20090270734A1
公开(公告)日：2009-10-29
申请号：US12109873
申请日：2008-04-25
IPC分类号： A61B8/06
CPC分类号： A61B5/026 , A61B5/031 , A61B8/0808
摘要： A non-invasive method for monitoring of cerebrovascular blood flow autoregulation state includes sensing intracranial blood volume waves, filtering a slow wave, respiratory wave, and pulse wave informative components from said intracranial blood volume waves, filtering slow wave and respiratory wave reference components from the pulse wave envelope, calculating a first phase shift between said slow wave informative component and said slow wave reference component, calculating a second phase shift between said respiratory wave informative component and said respiratory wave reference component, and calculating the index of evaluation of the status of cerebral autoregulation state (ICAS) from said first phase shift and said second phase shift.
摘要翻译： 用于监测脑血管血流自动调节状态的非侵入性方法包括从所述颅内血容量波感测颅内血容积波，过滤慢波，呼吸波和脉搏波信息成分，从慢性波和呼吸波参考成分过滤 计算所述慢波信息分量和所述慢波参考分量之间的第一相移，计算所述呼吸波信息成分与所述呼吸波参考分量之间的第二相移，并计算所述慢波信息分量的状态的评估指标 所述第一相移和所述第二相移的脑自动调节状态（ICAS）。
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17.发明授权Method and apparatus for non-invasively deriving and indicating of dynamic characteristics of the human and animal intracranial media 失效用于非侵入性地导出和指示人和动物颅内媒体的动态特征的方法和装置
公开(公告)号：US5388583A
公开(公告)日：1995-02-14
申请号：US115439
申请日：1993-09-01
CPC分类号： A61B5/031 , A61B8/04 , A61B8/0808 , A61B5/4064
摘要： An ultrasonic non-invasive technique is descried for deriving the time dependencies of characteristics of certain regions in the intracranium medium. Precise measurements of the transit travel times of acoustic pulses are made and processed to extract variable portions indicative of, for example, the pulsatility due to cardiac pulses of a basal artery or a cerebroventricle or the variation in the pressure of brain tissue, as well as changes in the cross-sectional dimension of the basal artery and ventricle. In one technique, the transit time variations attributable to cardiac pulses are extracted by processing higher harmonics in the frequency domain. Frequency and phase detection techniques are described.
摘要翻译： 描述了一种超声波非侵入性技术，用于导出颅内培养基中某些区域的特征的时间依赖性。 对声脉冲的传送行进时间的精确测量被制作和处理以提取指示例如由于基础动脉或脑室的心脏脉搏或脑组织的压力变化引起的搏动的可变部分，以及 基底动脉和心室的横截面尺寸的变化。 在一种技术中，通过处理频域中的高次谐波来提取归因于心脏脉冲的通过时间变化。 描述了频率和相位检测技术。
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公开(公告)号：US20180296182A1
公开(公告)日：2018-10-18
申请号：US15941919
申请日：2018-03-30
申请人： Jonathan Maltz , Arminas Ragauskas
发明人： Jonathan Maltz , Arminas Ragauskas
摘要： An apparatus and method for noninvasively measuring intracranial pressure of a subject using an ultrasound transducer. The transducer is used to measure arterial wall movement of an intracranial segment and an extracranial segment of the subject's ophthalmic artery as different external pressure forces are applied to the orbital area of the subject. When the waveforms of arterial wall movement between the intracranial segment and the extracranial segment are similar the intracranial pressure can be determined.
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19.发明申请Head Frame with Integrated Pressure Chamber for Non-Invasive Intracranial Pressure Measurements 审中-公开头部框架与集成压力室非侵入性颅内压测量公开(公告)号：US20160022246A1
公开(公告)日：2016-01-28
申请号：US14339982
申请日：2014-07-24
申请人： Arminas Ragauskas
发明人： Arminas Ragauskas
CPC分类号： A61B8/4272 , A61B5/031 , A61B5/4064 , A61B5/489 , A61B5/6803 , A61B5/6821 , A61B5/6831 , A61B8/06 , A61B8/10 , A61B8/42 , A61B8/488 , A61B8/5223 , Y10S901/44
摘要： A head frame for use in non-invasively determining the absolute value of intracranial pressure of a living body having a hard, flexible shield for covering the eye area of a patient. The shield has an inner surface and an outer transducer surface. An elastic film is sealed along its outer edge to the inner surface of the shield forming an expandable chamber. First and second connectors are located on the shield, permitting an inflow and outflow of pressurized liquid to the chamber. The elastic film expands inward toward the patient with an inflow of pressurized liquid, imparting a pressure against the patient's eye. An adjustable strap is attached to the shield for securing the head frame to the head of the patient.
摘要翻译： 一种头架，用于非侵入性地确定具有用于覆盖患者眼睛区域的硬的柔性护罩的活体的颅内压绝对值。 屏蔽件具有内表面和外传感器表面。 弹性膜沿其外边缘密封到屏蔽件的内表面，形成可膨胀室。 第一和第二连接器位于护罩上，允许加压液体流入和流出到腔室。 弹性膜以加压液体的流入朝向患者向内膨胀，对患者的眼睛施加压力。 将可调节的带子连接到护罩上，以将头部框架固定到患者的头部。
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20.发明授权公开(公告)号：US07147605B2
公开(公告)日：2006-12-12
申请号：US10615186
申请日：2003-07-08
申请人： Arminas Ragauskas
发明人： Arminas Ragauskas
CPC分类号： A61B5/6814 , A61B5/0053 , A61B5/031 , A61B5/6817
摘要： A device for obtaining an indication of the intracranial pressure of a living body includes a positional sensor which determines an initial position of an elastic biological object when the intracranial pressure within the living body is zero and which determines a subsequent position of the elastic biological object when the intracranial pressure within the living body is unknown but greater than zero. A pressure generator applies an external pressure to the elastic biological object, and a comparator compares the initial position with the subsequent position so as to identify the unknown intracranial pressure of the living body as that external pressure which causes the subsequent position to be equal to the initial position.
摘要翻译： 用于获得生物体的颅内压的指示的装置包括位置传感器，其当生物体内的颅内压为零时确定弹性生物体的初始位置，并且确定弹性生物体的后续位置， 生物体内的颅内压未知但大于零。 压力发生器对弹性生物体施加外部压力，并且比较器将初始位置与随后的位置进行比较，以便识别生物体的未知颅内压，因为外部压力导致随后的位置等于 初始位置
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