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    Methods and systems for in situ tissue marking and orientation stabilization
    14.
    发明授权
    Methods and systems for in situ tissue marking and orientation stabilization 失效
    用于原位组织标记和取向稳定的方法和系统

    公开(公告)号：US06780179B2

    公开(公告)日：2004-08-24

    申请号：US10155570

    申请日：2002-05-22

    申请人： Roberta Lee ,  James W. Vetter ,  Ary S. Chernomorsky

    发明人： Roberta Lee ,  James W. Vetter ,  Ary S. Chernomorsky

    IPC分类号： A61B1818

    CPC分类号： A61B10/0266 ,  A61B18/148 ,  A61B2018/00333 ,  A61B2018/00601 ,  A61B2018/141 ,  A61B2018/1475 ,  A61B2090/3908 ,  A61B2090/3937 ,  A61B2090/395

    摘要： A method of marking an orientation of a cut specimen of tissue prior to excision thereof from a body includes steps of disposing a tissue-marking probe in the body adjacent the cut specimen, the tissue-marking probe including a tissue-marking tool configured to selectively mark the cut specimen. A surface of the cut specimen is then marked with the tissue-marking tool such that the orientation of the cut specimen within the body is discernable after the cut specimen is excised from the body. The tissue-marking tool may be configured to selectively bow out of and back into a window defined near a distal tip of the probe and the marking step may include a step of selectively bowing the tissue-marking tool out of the window and following the surface of the cut specimen while rotating the probe. The tissue-marking tool may include an RF cutting tool and the marking step may include a step of coagulating or cauterizing a selected portion of the surface of the cut specimen with the RF cutting tool. Alternatively, the marking step may include a step of delivering dye onto selected portions of the surface of the cut specimen.

    摘要翻译： 在从身体切除之前标记组织切割样本的取向的方法包括以下步骤：将组织标记探针设置在与切割的样本相邻的身体中，组织标记探针包括组织标记工具，其被配置为选择性地 标记切割标本。 然后用组织标记工具标记切割的样品的表面，使得在切割的样品从身体切除之后，切割的样品在体内的取向是可辨别的。 组织标记工具可以被配置为选择性地弯曲到限定在探针的远侧末端附近的窗口中，并且标记步骤可以包括将组织标记工具选择性地弯曲出窗户并且跟随表面的步骤 同时旋转探头。 组织标记工具可以包括RF切割工具，并且标记步骤可以包括用RF切割工具凝固或烧灼切割样品表面的选定部分的步骤。 或者，标记步骤可以包括将染料递送到切割样品的表面的选定部分上的步骤。

    METHODS AND DEVICES FOR CUTTING AND COLLECTING SOFT TISSUE
    17.
    发明申请
    METHODS AND DEVICES FOR CUTTING AND COLLECTING SOFT TISSUE 有权
    用于切割和收集软组织的方法和装置

    公开(公告)号：US20120035503A1

    公开(公告)日：2012-02-09

    申请号：US13275273

    申请日：2011-10-17

    申请人： James W. Vetter ,  Ary S. Chernomorsky ,  Mark J. Clifford ,  Dan Brounstein ,  Scott C. Anderson

    发明人： James W. Vetter ,  Ary S. Chernomorsky ,  Mark J. Clifford ,  Dan Brounstein ,  Scott C. Anderson

    IPC分类号： A61B10/02

    CPC分类号： A61B10/0266 ,  A61B2017/00287 ,  A61B2017/008 ,  A61B2018/1407

    摘要： Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.

    摘要翻译： 从大量组织切割和收集标本的装置和方法。 该装置可以包括集成的切割和收集组件。 集成的切割和收集组件包括切割部分和包括柔性膜的收集部分。 组件的收集部分附接到其切割部分。 切割部分被构造成从组织块切割样本，并且收集部分被配置为收集切割的样本并且将切割的样本包封并分离在膜内以使其能够从组织块的安全回缩。

    Excisional biopsy devices and methods
    19.
    发明授权
    Excisional biopsy devices and methods 失效
    切除活检装置和方法

    公开(公告)号：US06440147B1

    公开(公告)日：2002-08-27

    申请号：US09565611

    申请日：2000-05-04

    申请人： Roberta Lee ,  James W. Vetter ,  Ary S. Chernomorsky

    发明人： Roberta Lee ,  James W. Vetter ,  Ary S. Chernomorsky

    IPC分类号： A61B1732

    CPC分类号： A61B10/0266 ,  A61B10/0041 ,  A61B10/02 ,  A61B10/04 ,  A61B17/320725 ,  A61B18/1482 ,  A61B2018/00011 ,  A61B2018/00333 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2090/3784 ,  A61B2218/002

    摘要： An excisional biopsy system includes a tubular member that has a proximal end and a distal end in which one or more windows are defined. A first removable probe has a proximal portion that includes a cutting tool extender and a distal portion that includes a cutting tool. The first removable probe may be configured to fit at least partially within the tubular member to enable the cutting tool to selectively bow out of and to retract within one of the windows when the cutting tool extender is activated. A second removable probe has a proximal section that includes a tissue collection device extender and a distal section that includes a tissue collection device. The second removable probe may also be configured to fit at least partially within the tubular member to enable the tissue collection device to extend out of and to retract within one of the windows when the tissue collection device extender is activated. A third removable probe may also be provided. The third removable probe may also be configured to fit at least partially within the tubular member and may include an imaging device, such as an ultrasound transducer, mounted therein. By selectively activating the cutting tool and the tissue collection device while rotating the excisional device, a tissue specimen may be cut from the surrounding tissue and collected for later analysis.

    摘要翻译： 切除活检系统包括管状构件，其具有限定一个或多个窗口的近端和远端。 第一可移除探针具有近端部分，其包括切削刀具延伸器和包括切削工具的远端部分。 第一可移除探针可以被配置为至少部分地配合在管状构件内，以使得当切割工具延伸器被激活时，切割工具能够选择性地弯曲在一个窗口内并缩回。 第二可移除探针具有近端部分，其包括组织收集装置延伸器和包括组织收集装置的远端部分。 第二可移除探针也可以被配置为至少部分地配合在管状构件内，以使组织收集装置在组织收集装置延伸器被启动时延伸出窗口内的一个窗口并缩回。 还可以提供第三可移除探针。 第三可移除探针也可以被配置为至少部分地配合在管状构件内，并且可以包括安装在其中的成像装置，例如超声换能器。 通过在旋转切除装置的同时选择性地激活切割工具和组织收集装置，可以从周围组织切割组织标本并收集用于随后的分析。

    Post-biopsy cavity treatment implants and methods
    20.
    发明授权
    Post-biopsy cavity treatment implants and methods 失效
    活检后腔内治疗植入物和方法

    公开(公告)号：US08491630B2

    公开(公告)日：2013-07-23

    申请号：US13564713

    申请日：2012-08-01

    申请人： Ary S. Chernomorsky ,  James W. Vetter ,  Simon Chernomorsky

    发明人： Ary S. Chernomorsky ,  James W. Vetter ,  Simon Chernomorsky

    IPC分类号： A61B17/08

    CPC分类号： A61M31/005 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00654 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/04 ,  A61L31/146 ,  A61L31/18

    摘要： An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.

    摘要翻译： 用于填充由切除过程产生的空腔的植入物包括第一和第二部分。 第一部分可以包括限定第一选择的交联密度的第一胶原基质，并且第二部分可以包括限定不同于第一交联密度的第二选择的交联密度的第二胶原基质。 可以选择第一和第二交联密度以使得第一和第二部分以这样的方式膨胀，使得当第一和第二部分的膨胀成为与腔的预定尺寸和形状相似的尺寸和形状时，当 植入植入物。 如果空腔不足够水以引起植入物膨胀，则可将水溶液加入空腔中。