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公开(公告)号：US08491630B2
公开(公告)日：2013-07-23
申请号：US13564713
申请日：2012-08-01
IPC分类号： A61B17/08
CPC分类号： A61M31/005 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3987 , A61K49/04 , A61L31/146 , A61L31/18
摘要： An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.
摘要翻译： 用于填充由切除过程产生的空腔的植入物包括第一和第二部分。 第一部分可以包括限定第一选择的交联密度的第一胶原基质，并且第二部分可以包括限定不同于第一交联密度的第二选择的交联密度的第二胶原基质。 可以选择第一和第二交联密度以使得第一和第二部分以这样的方式膨胀，使得当第一和第二部分的膨胀成为与腔的预定尺寸和形状相似的尺寸和形状时，当 植入植入物。 如果空腔不足够水以引起植入物膨胀，则可将水溶液加入空腔中。
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公开(公告)号：US20110052505A1
公开(公告)日：2011-03-03
申请号：US12806890
申请日：2010-08-23
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US07780948B2
公开(公告)日：2010-08-24
申请号：US12256619
申请日：2008-10-23
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US20090263442A1
公开(公告)日：2009-10-22
申请号：US12256619
申请日：2008-10-23
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US20120076733A1
公开(公告)日：2012-03-29
申请号：US13309504
申请日：2011-12-01
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US07537788B2
公开(公告)日：2009-05-26
申请号：US10688289
申请日：2003-10-16
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US08092779B2
公开(公告)日：2012-01-10
申请号：US12806890
申请日：2010-08-23
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A post-biopsy cavity treatment implant includes a radiopaque element, a core portion and a shell portion. The core portion is coupled to the radiopaque element, and includes a first porous matrix defining a first controlled pore architecture. The shell portion is coupled to the core portion and includes a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture.
摘要翻译： 活检后腔治疗植入物包括不透射线元件，芯部分和壳部分。 芯部分耦合到不透射线的元件，并且包括限定第一受控孔结构的第一多孔基体。 壳部分耦合到芯部分并且包括限定与第一受控孔结构不同的第二受控孔结构的第二多孔基质。
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公开(公告)号：US07534452B2
公开(公告)日：2009-05-19
申请号：US12018170
申请日：2008-01-22
CPC分类号： A61L31/146 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61K49/04 , A61L31/18
摘要： A method of treating a cavity created by a percutaneous excisional procedure carried out through an incision includes steps of providing a post-procedure cavity implant, the post-procedure cavity implant including: a radiopaque element; a core portion coupled to the radiopaque element, the core portion including a first porous matrix defining a first controlled pore architecture, and a shell portion coupled to the core portion, the shell portion including a second porous matrix defining a second controlled pore architecture that is different from the first controlled pore architecture; implanting the post-procedure cavity implant into the cavity, and closing the incision.
摘要翻译： 一种治疗由通过切口进行的经皮切除手术产生的腔的方法包括提供后程腔腔植入物的步骤，所述后程腔腔植入物包括：不透射线的元件; 芯部分，其连接到所述不透射线元件，所述芯部分包括限定第一受控孔结构的第一多孔基体和耦合到所述芯部分的壳部分，所述壳部分包括限定第二受控孔结构的第二多孔基体， 不同于第一受控孔结构; 将后程腔腔植入物植入腔中，并闭合切口。
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公开(公告)号：US09603586B2
公开(公告)日：2017-03-28
申请号：US13275273
申请日：2011-10-17
CPC分类号： A61B10/0266 , A61B2017/00287 , A61B2017/008 , A61B2018/1407
摘要： Devices and methods for cutting and collecting a specimen from a mass of tissue. The device may include an integrated cut and collect assembly. The integrated cut and collect assembly includes a cutting portion and a collection portion that includes a flexible membrane. The collection portion of the assembly is attached to the cutting portion thereof. The cutting portion is configured to cut the specimen from the mass of tissue and the collection portion is configured to collect the cut specimen and to encapsulate and isolate the cut specimen within the membrane to enable its safe retraction from the mass of tissue.
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公开(公告)号：US20120296207A1
公开(公告)日：2012-11-22
申请号：US13564713
申请日：2012-08-01
IPC分类号： A61B6/00
CPC分类号： A61M31/005 , A61B17/0057 , A61B90/39 , A61B2017/00654 , A61B2090/3908 , A61B2090/3987 , A61K49/04 , A61L31/146 , A61L31/18
摘要： An implant for filling a cavity created by an excisional procedure includes first and second portions. The first portion may include a first collagenous matrix that defines a first selected crosslinking density and the second portion may include a second collagenous matrix that defines a second selected cross-linking density that is different than the first cross-linking density. The first and second cross-linking densities may be selected so as to cause the first and second portions to swell in such a manner that the implant swells into a size and a shape that is similar to the predetermined size and shape of the cavity when the implant is implanted. An aqueous solution may be added to the cavity if the cavity is not sufficiently aqueous to cause the implant to swell.
摘要翻译： 用于填充由切除过程产生的空腔的植入物包括第一和第二部分。 第一部分可以包括限定第一选择的交联密度的第一胶原基质，并且第二部分可以包括限定不同于第一交联密度的第二选择的交联密度的第二胶原基质。 可以选择第一和第二交联密度以使得第一和第二部分以这样的方式膨胀，使得当第一和第二部分的膨胀成为与腔的预定尺寸和形状相似的尺寸和形状时，当 植入植入物。 如果空腔不足够水以引起植入物膨胀，则可将水溶液加入空腔中。
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