-
Patent Agency Ranking
公开(公告)号：US11337970B2
公开(公告)日：2022-05-24
申请号：US16328449
申请日：2017-08-25
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Emily Charlotte Cherney , Weifang Shan , Liping Zhang , Susheel Jethanand Nara , Audris Huang , James Aaron Balog
IPC: A61K31/4709 , A61K31/4375 , A61K31/5025 , A61K31/517 , A61K39/395 , C07D401/08 , C07D401/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04 , C07D491/056
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
-
公开(公告)号：US11066383B2
公开(公告)日：2021-07-20
申请号：US16098245
申请日：2017-05-04
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David K. Williams , Weifang Shan , Liping Zhang , Emily Charlotte Cherney , James Aaron Balog
IPC: C07D401/04 , C07D401/06 , C07D215/46 , C07D215/14 , A61P35/00 , A61K31/444 , A61K31/47 , A61K31/4709 , A61K31/496 , C07D215/18
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
-
公开(公告)号：US09783573B2
公开(公告)日：2017-10-10
申请号：US14428688
申请日：2013-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Robert M. Borzilleri , Kyoung S. Kim , Heidi L. Perez , Erik M. Stang , David K. Williams , Liping Zhang
IPC: C07K5/08 , C07K5/083 , A61K38/06 , A61K45/06 , C07D401/14 , C07D413/14 , C07D401/06 , C07D401/10 , C07D401/12 , C07D417/14 , C07D487/04
CPC classification number: C07K5/0806 , A61K38/06 , A61K45/06 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
-
公开(公告)号：US09603889B2
公开(公告)日：2017-03-28
申请号：US14432517
申请日：2013-10-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Kyoung S. Kim , Liping Zhang , Donna D. Wei
CPC classification number: A61K38/08 , A61K38/00 , A61K45/06 , C07K5/0806 , C07K7/06
Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
-
公开(公告)号：US20150322111A1
公开(公告)日：2015-11-12
申请号：US14428688
申请日：2013-09-17
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Robert M. Borzilleri , Kyoung S. Kim , Heidi L. Perez , Erik M. Stang , David K. Williams , Liping Zhang
CPC classification number: C07K5/0806 , A61K38/06 , A61K45/06 , C07D401/06 , C07D401/10 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: There are disclosed compounds of formula (I) that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Abstract translation: 公开了利用本发明化合物调节凋亡抑制剂（IAP）的活性的式（I）化合物，含有所述化合物的药物组合物和治疗增殖性疾病的方法和失调性细胞凋亡障碍（例如癌症）的化合物。
-
-
-
-
Search Results
15
records
(took 0.026 seconds)
