公开(公告)号：US20170275272A1

公开(公告)日：2017-09-28

申请号：US15468230

申请日：2017-03-24

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Zulan Pi ,  Donna M. Bilder ,  Robert Paul Brigance ,  Heather Finlay ,  Wen Jiang ,  James A. Johnson ,  R. Michael Lawrence ,  Wei Meng ,  Michael C. Myers ,  Monique Phillips ,  George O. Tora ,  Xiaojun Zhang

IPC: C07D403/06 ,  C07D471/04 ,  C07D417/14 ,  C07D401/14

CPC classification number: C07D403/06 ,  A61K31/505 ,  C07D239/54 ,  C07D239/545 ,  C07D239/557 ,  C07D401/06 ,  C07D401/14 ,  C07D403/02 ,  C07D403/14 ,  C07D417/14 ,  C07D471/04

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.

公开(公告)号：US10590113B2

公开(公告)日：2020-03-17

申请号：US16122975

申请日：2018-09-06

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Zulan Pi ,  Donna M. Bilder ,  Robert Paul Brigance ,  Heather Finlay ,  Wen Jiang ,  James A. Johnson ,  R. Michael Lawrence ,  Wei Meng ,  Michael C. Myers ,  Monique Phillips ,  George O. Tora ,  Xiaojun Zhang

IPC: A61K31/505 ,  C07D403/06 ,  C07D401/06 ,  C07D403/14 ,  C07D239/557 ,  C07D239/54 ,  C07D239/545 ,  C07D401/14 ,  C07D403/02 ,  C07D417/14 ,  C07D471/04

Abstract: The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are APJ agonists which may be used as medicaments.