公开(公告)号：US11913954B2

公开(公告)日：2024-02-27

申请号：US17170577

申请日：2021-02-08

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/53 ,  G01N33/571 ,  G01N33/543 ,  G01N33/92

CPC classification number: G01N33/571 ,  G01N33/543 ,  G01N33/54313 ,  G01N33/92 ,  G01N2333/20 ,  G01N2405/04 ,  G01N2469/20

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US10324091B2

公开(公告)日：2019-06-18

申请号：US15701272

申请日：2017-09-11

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/53 ,  G01N33/571 ,  G01N33/543 ,  G01N33/92

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US10067135B2

公开(公告)日：2018-09-04

申请号：US15897040

申请日：2018-02-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: C12Q1/68 ,  C12Q1/70 ,  A61K39/00 ,  A61K38/00 ,  C07H21/04 ,  G01N33/576 ,  G01N33/543

CPC classification number: G01N33/5761 ,  G01N33/54326

Abstract: Provided herein are multiplex assays for determining whether an individual is or has been infected with Hepatitis B virus, and the stage of infection or resolution. In addition, the multiplex system can discriminate between vaccinated subjects and subjects susceptible to Hepatitis B infection.