公开(公告)号：US10942182B2

公开(公告)日：2021-03-09

申请号：US16832608

申请日：2020-03-27

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/543 ,  G01N33/92

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US20140323332A1

公开(公告)日：2014-10-30

申请号：US14261525

申请日：2014-04-25

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/576

CPC classification number: G01N33/5761 ,  G01N33/54326

Abstract: Provided herein are multiplex assays for determining whether an individual is or has been infected with Hepatitis B virus, and the stage of infection or resolution. In addition, the multiplex system can discriminate between vaccinated subjects and subjects susceptible to Hepatitis B infection.

Abstract translation: 本文提供用于确定个体是否已经感染乙型肝炎病毒的多重测定，以及感染或分辨的阶段。 此外，多重系统可以区分接种的受试者和易感乙型肝炎感染的受试者。

公开(公告)号：US20170370931A1

公开(公告)日：2017-12-28

申请号：US15701272

申请日：2017-09-11

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/543 ,  G01N33/92

CPC classification number: G01N33/571 ,  G01N33/543 ,  G01N33/54313 ,  G01N33/92 ,  G01N2333/20 ,  G01N2405/04 ,  G01N2469/20

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US20190265240A1

公开(公告)日：2019-08-29

申请号：US16405588

申请日：2019-05-07

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/92 ,  G01N33/543

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US20180172687A1

公开(公告)日：2018-06-21

申请号：US15897040

申请日：2018-02-14

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/576 ,  G01N33/543

CPC classification number: G01N33/5761 ,  G01N33/54326

Abstract: Provided herein are multiplex assays for determining whether an individual is or has been infected with Hepatitis B virus, and the stage of infection or resolution. In addition, the multiplex system can discriminate between vaccinated subjects and subjects susceptible to Hepatitis B infection.

公开(公告)号：US09927439B2

公开(公告)日：2018-03-27

申请号：US14261525

申请日：2014-04-25

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: C12Q1/68 ,  C12Q1/70 ,  A61K39/00 ,  A61K39/29 ,  C07K14/005 ,  G01N33/576 ,  G01N33/543

CPC classification number: G01N33/5761 ,  G01N33/54326

Abstract: Provided herein are multiplex assays for determining whether an individual is or has been infected with Hepatitis B virus, and the stage of infection or resolution. In addition, the multiplex system can discriminate between vaccinated subjects and subjects susceptible to Hepatitis B infection.

公开(公告)号：US20210156859A1

公开(公告)日：2021-05-27

申请号：US17170577

申请日：2021-02-08

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/543 ,  G01N33/92

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US20200225230A1

公开(公告)日：2020-07-16

申请号：US16832608

申请日：2020-03-27

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/543 ,  G01N33/92

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US10648981B2

公开(公告)日：2020-05-12

申请号：US16405588

申请日：2019-05-07

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/53 ,  G01N33/571 ,  G01N33/543 ,  G01N33/92

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.

公开(公告)号：US20240248086A1

公开(公告)日：2024-07-25

申请号：US18437816

申请日：2024-02-09

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Ravi Kaul ,  Weiming Zheng ,  Roger Walker

IPC: G01N33/571 ,  G01N33/543 ,  G01N33/92

CPC classification number: G01N33/571 ,  G01N33/543 ,  G01N33/54313 ,  G01N33/92 ,  G01N2333/20 ,  G01N2405/04 ,  G01N2469/20

Abstract: Provided herein are multiplex assays for detecting antibodies indicative of presence and stage of syphilis infection in an individual. Individuals infected with syphilis produce antibodies directed to syphilis components and the lipid cellular debris associated with the infection. The present disclosure represents the first combination of these diverse antibody targets in a single assay.