公开(公告)号：US08221529B2

公开(公告)日：2012-07-17

申请号：US13301306

申请日：2011-11-21

申请人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

发明人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

IPC分类号： B01D19/00

CPC分类号： A61M1/1658 ,  A61M1/166 ,  A61M1/3627 ,  A61M2205/128

摘要： In an embodiment, a dialysis fluid cassette is disclosed. The cassette includes a plurality of walls defining at least one valve chamber, a dialysis fluid inlet, a dialysis fluid outlet and a dialysis fluid pathway. The cassette further includes a baffle extending from a first one of the walls to an opposing second one of the walls. The baffle includes an end fixed to a third one of the plurality of walls and a free end. The fixed end separates the dialysis fluid inlet from the dialysis fluid outlet and the baffle and the plurality of walls are constructed and arranged such that the flow of dialysis fluid along the pathway defined in part by the baffle slows as the flow approaches the free end of the baffle.

摘要翻译： 在一个实施例中，公开了一种透析流体盒。 盒子包括限定至少一个阀室，透析流体入口，透析流体出口和透析流体通道的多个壁。 所述盒还包括从所述壁中的第一壁延伸到相对的第二壁之间的挡板。 挡板包括固定到多个壁中的第三个壁的端部和自由端。 固定端将透析流体入口与透析流体出口和挡板分离，并且构造和布置多个壁，使得沿着部分由挡板限定的路径的透析流体的流动随着流体接近自由端的速度而减慢 挡板。

公开(公告)号：US20110144557A1

公开(公告)日：2011-06-16

申请号：US13030855

申请日：2011-02-18

申请人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

发明人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

IPC分类号： A61M1/14 ,  A61M1/28

CPC分类号： A61M1/1658 ,  A61M1/166 ,  A61M1/3627 ,  A61M2205/128

摘要： A dialysis fluid system includes an instrument including a pump actuator and a fluid heater, and a dialysis fluid cassette. The dialysis fluid cassette includes a rigid portion defining a pumping section for operation with the pump actuator and a heating section for operation with the fluid heater. The heating section includes a dialysis fluid inlet, a dialysis fluid outlet, and a dialysis fluid heating area located between the fluid inlet and the fluid outlet, the heating section further includes an air separation chamber for collecting air separated from the dialysis fluid.

摘要翻译： 透析液系统包括包括泵致动器和流体加热器的仪器以及透析液盒。 透析液盒包括限定用于与泵致动器一起操作的泵送部分的刚性部分和用于与流体加热器一起操作的加热部分。 加热部分包括透析流体入口，透析液出口和位于流体入口和流体出口之间的透析流体加热区域，加热部分还包括用于收集从透析液分离的空气的空气分离室。

公开(公告)号：US20110137237A1

公开(公告)日：2011-06-09

申请号：US13027824

申请日：2011-02-15

申请人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

发明人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

IPC分类号： A61M1/28 ,  B01D19/00 ,  B01D61/28 ,  B01D61/30

CPC分类号： A61M1/1658 ,  A61M1/288 ,  A61M1/3627 ,  A61M2205/12 ,  A61M2205/128 ,  B01D19/0042

摘要： A dialysis system includes a dialysis fluid disposable configured to hold and transport a dialysis fluid; an air separation chamber in fluid communication with the dialysis fluid disposable; and a dialysis instrument operable to pump dialysis fluid through the dialysis fluid disposable, the instrument including a vibrator configured to vibrate the air separation chamber to separate air from the dialysis fluid traveling through the chamber.

摘要翻译： 透析系统包括：一次性透析液，被配置为保持和运送透析液; 与透析液流体连通的空气分离室一次性; 以及透析器，其可操作以将透析流体泵送通过所述一次性透析液，所述器械包括振动器，所述振动器被配置为使所述空气分离室振动以将空气与穿过所述腔室的透析流体分离。

公开(公告)号：US20110137236A1

公开(公告)日：2011-06-09

申请号：US13030624

申请日：2011-02-18

申请人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

发明人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

IPC分类号： A61M5/36 ,  A61M1/28

CPC分类号： A61M1/1658 ,  A61M1/288 ,  A61M1/3627 ,  A61M2205/12 ,  A61M2205/128 ,  B01D19/0042

摘要： A medical fluid delivery system includes a fluid disposable configured to hold and transport a medical fluid and an air separation chamber in fluid communication with the fluid disposable. The air separation chamber includes at least one fluid baffle floating within the air separation chamber and configured to separate air from medical fluid traveling through the chamber.

摘要翻译： 医疗流体输送系统包括流体一次性，其被配置为保持和输送医疗流体和与流体一次性流体连通的空气分离室。 空气分离室包括漂浮在空气分离室内的至少一个流体挡板并且构造成将空气与行进通过该室的医用流体分离。

公开(公告)号：US06712095B2

公开(公告)日：2004-03-30

申请号：US10266002

申请日：2002-10-07

申请人： Mark E. Williamson ,  Scott R. Ariagno ,  Alan W. Marttila ,  Arnold C. Bilstad ,  Paul M. DiPerna ,  Michael R. Prisco ,  David W. Pennington ,  Atif M. Yardimci ,  Sidney T. Smith ,  Mark C. Perry ,  Marc Bellotti

发明人： Mark E. Williamson ,  Scott R. Ariagno ,  Alan W. Marttila ,  Arnold C. Bilstad ,  Paul M. DiPerna ,  Michael R. Prisco ,  David W. Pennington ,  Atif M. Yardimci ,  Sidney T. Smith ,  Mark C. Perry ,  Marc Bellotti

IPC分类号： F16K1514

CPC分类号： A61J7/0053 ,  A47G21/185 ,  A61J1/10 ,  A61J1/1475 ,  A61J7/0046 ,  A61M39/227 ,  A61M39/24 ,  A61M2039/2406 ,  A61M2039/242 ,  A61M2039/244 ,  A61M2039/2486 ,  F16K15/14 ,  F16K15/147 ,  Y10S137/907 ,  Y10T137/7781 ,  Y10T137/7836 ,  Y10T137/7882 ,  Y10T137/789

摘要： A vacuum demand valve for delivering a flowable material is disclosed. The valve has a housing having a proximal end, a distal end, an intermediate segment therebetween defining a passageway wherein the flowable substance can flow from the proximal end to the distal end. The housing can be a tubing. A valve member is located along the intermediate segment. The valve member has a closed condition wherein the flow of the flowable material from the proximal end to the distal end is stopped and an open condition wherein the flow of the flowable material from the proximal end to the distal end is unstopped. The valve member is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway for placing the valve member in the open condition.

摘要翻译： 公开了一种用于输送可流动材料的真空需求阀。 阀具有壳体，其具有近端，远端，间隔开的中间段，其中可流动物质可以从近端流到远端。 外壳可以是管道。 阀构件沿着中间段定位。 阀构件具有闭合状态，其中可流动材料从近端到远端的流动停止，并且打开状态，其中可流动材料从近端到远端的流动不被阻挡。 阀构件在关闭状态下被偏置并且响应于用户通过通道提供的部分真空，以将阀构件置于打开状态。

公开(公告)号：US06550493B2

公开(公告)日：2003-04-22

申请号：US09880720

申请日：2001-06-13

申请人： Mark E. Williamson ,  Scott R. Ariagno ,  Alan W. Marttila ,  Arnold C. Bilstad ,  Paul M. DiPerna ,  Michael R. Prisco ,  David W. Pennington ,  Atif M. Yardimci ,  Sidney T. Smith ,  Mark C. Perry ,  Marc Bellotti

发明人： Mark E. Williamson ,  Scott R. Ariagno ,  Alan W. Marttila ,  Arnold C. Bilstad ,  Paul M. DiPerna ,  Michael R. Prisco ,  David W. Pennington ,  Atif M. Yardimci ,  Sidney T. Smith ,  Mark C. Perry ,  Marc Bellotti

IPC分类号： F16K31126

CPC分类号： A61J7/0053 ,  A47G21/185 ,  A61J1/10 ,  A61J1/1475 ,  A61J7/0046 ,  A61M39/227 ,  A61M39/24 ,  A61M2039/2406 ,  A61M2039/242 ,  A61M2039/244 ,  A61M2039/2486 ,  F16K15/14 ,  F16K15/147 ,  Y10S137/907 ,  Y10T137/7781 ,  Y10T137/7836 ,  Y10T137/7882 ,  Y10T137/789

摘要： A vacuum demand value (10) is capable of delivering a flowable material. The valve (10) has a housing (11) having a proximal end (14), a distal end (16), an intermediate segment (18) therebetween defining a passageway (24) wherein the flowable substance can flow from the proximal end (14) to the distal end (16). The housing (11) can be tubing. A valve member (20) is located along the intermediate segment (18). The valve member (20) has a closed condition wherein the flowable material from the proximal end (14) to the distal end (16) is stopped and an open condition wherein the flow of the flowable material from the proximal end (14) to the distal end (16) is unstopped. The valve member (20) is biased in the closed condition and is responsive to a partial vacuum provided by the user through the passageway (24) for placing the valve member (20) in the open condition.

摘要翻译： 真空需求值（10）能够输送可流动的材料。 阀（10）具有壳体（11），其具有近端（14），远端（16），间隔开的中间段（18），限定通道（24），其中可流动物质可以从近端（ 14）到远端（16）。 外壳（11）可以是管道。 阀构件（20）沿着中间段（18）定位。 阀构件（20）具有闭合状态，其中从近端（14）到远端（16）的可流动材料停止，并且打开状态，其中可流动材料从近端（14）流到 远端（16）不受阻挡。 阀构件（20）在关闭状态下被偏压并且响应于用户通过通道（24）提供的用于将阀构件（20）置于打开状态的部分真空。

公开(公告)号：US5628915A

公开(公告)日：1997-05-13

申请号：US472513

申请日：1995-06-07

申请人： Richard I. Brown ,  Michael R. Prisco

发明人： Richard I. Brown ,  Michael R. Prisco

IPC分类号： A61M1/02 ,  A61M1/30 ,  A61M1/36 ,  B01D17/02 ,  B01D21/24 ,  B01D21/26 ,  B04B1/06 ,  B04B5/04 ,  B04B7/08 ,  B04B13/00

CPC分类号： A61M1/0209 ,  A61M1/302 ,  A61M1/303 ,  A61M1/308 ,  A61M1/3603 ,  A61M1/3624 ,  A61M1/3693 ,  A61M1/3696 ,  B01D17/0217 ,  B01D21/2405 ,  B01D21/245 ,  B01D21/262 ,  B04B13/00 ,  B04B5/0442 ,  B04B7/08 ,  A61M1/025 ,  A61M1/30 ,  A61M2202/0427 ,  A61M2205/331 ,  A61M2205/3344 ,  A61M2205/3351 ,  A61M2205/3355 ,  A61M2205/3393 ,  B01D2221/10 ,  B04B2005/045

摘要： Blood processing systems and methods create dynamic vortex flow conditions within the processing chamber by conveying blood into a separation path that extends circumferentially about the rotational axis along an entry path that extends generally parallel to the rotational axis. The vortex flow conditions perfuse blood into the separation path for separation into component parts. The systems and methods confine the vortex flow pattern along the entry path by reducing the radial width of the entry path.

摘要翻译： 血液处理系统和方法通过将血液输送到沿着大体上平行于旋转轴线延伸的入口路径围绕旋转轴线周向延伸的分离路径而在处理室内产生动态涡流条件。 涡流条件将血液灌注到分离路径中，以分离成组分部分。 系统和方法通过减小进入路径的径向宽度来限制涡流图案沿入口路径。

公开(公告)号：US08025716B2

公开(公告)日：2011-09-27

申请号：US13030624

申请日：2011-02-18

申请人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

发明人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

IPC分类号： B01D19/00

CPC分类号： A61M1/1658 ,  A61M1/288 ,  A61M1/3627 ,  A61M2205/12 ,  A61M2205/128 ,  B01D19/0042

摘要： A medical fluid delivery system includes a fluid disposable configured to hold and transport a medical fluid and an air separation chamber in fluid communication with the fluid disposable. The air separation chamber includes at least one fluid baffle floating within the air separation chamber and configured to separate air from medical fluid traveling through the chamber.

摘要翻译： 医疗流体输送系统包括流体一次性，其被配置为保持和输送医疗流体和与流体一次性流体连通的空气分离室。 空气分离室包括漂浮在空气分离室内的至少一个流体挡板并且构造成将空气与行进通过该室的医用流体分离。

公开(公告)号：US07892332B2

公开(公告)日：2011-02-22

申请号：US11865577

申请日：2007-10-01

申请人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

发明人： Michael R. Prisco ,  Atif M. Yardimci ,  Serhan Acikgoz ,  James C. Laird ,  Shincy J. Maliekkal ,  Justin B. Rohde

IPC分类号： B01D19/00

CPC分类号： A61M1/1658 ,  A61M1/288 ,  A61M1/3627 ,  A61M2205/12 ,  A61M2205/128 ,  B01D19/0042

摘要： A dialysis fluid cassette includes a rigid portion defining first and second valve chambers, the rigid portion further defining an air separation chamber in fluid communication with the first and second valve chambers, the air separation chamber including a baffle and structured such that when the cassette is placed in a dialysis instrument, (i) the baffle extends upwardly from a bottom of the air separation chamber and (ii) first and second openings to the air separation chamber, communicating fluidly and respectively with the first and second valve chambers, are located near the bottom of the air separation chamber, such that the dialysis fluid is forced up one side of the baffle and down the other side of the baffle when flowing through the air separation chamber.

摘要翻译： 透析液体盒包括限定第一和第二阀室的刚性部分，刚性部分进一步限定与第一和第二阀室流体连通的空气分离室，空气分离室包括挡板并构造成使得当盒式磁带 放置在透析仪器中，（i）挡板从空气分离室的底部向上延伸，和（ii）第一和第二开口到达空气分离室，与第一和第二阀室流体连通，分别位于靠近 空气分离室的底部，使得透析流体在流过空气分离室时被迫上挡板的一侧并且在挡板的另一侧下方。

公开(公告)号：US07892331B2

公开(公告)日：2011-02-22

申请号：US11865583

申请日：2007-10-01

申请人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

发明人： Robert W. Childers ,  Donald D. Busby ,  Michael E. Hogard ,  Michael R. Prisco ,  Atif M. Yardimci ,  James C. Laird

IPC分类号： B01D19/00

CPC分类号： A61M1/1658 ,  A61M1/166 ,  A61M1/3627 ,  A61M2205/128

摘要： A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including a first sidewall and a second sidewall, a first fluid opening, a second fluid opening, and a separation wall extending from the first sidewall to the second sidewall, the separation wall having a free edge residing within the air separation chamber, the separation wall forcing the dialysis fluid to flow from one of the fluid openings around the free edge of the separation wall to the other of the openings.

摘要翻译： 透析液体盒包括限定至少一个阀室的刚性部分，所述刚性部分还限定空气分离室，所述空气分离室处于包括第一侧壁和第二侧壁的操作位置时，所述空气分离室，第一流体开口，第二流体开口 流体开口和从第一侧壁延伸到第二侧壁的分隔壁，分隔壁具有位于空气分离室内的自由边缘，分隔壁迫使透析流体围绕自由边缘的一个流体开口流动 的隔离壁到另一个开口。