公开(公告)号：US20210188827A1

公开(公告)日：2021-06-24

申请号：US17111307

申请日：2020-12-03

Applicant: CHDI Foundation, Inc.

Inventor： Leticia M. Toledo-Sherman ,  Celia Dominguez ,  Perla Breccia ,  Amanda J. Van De Poël ,  Grant Wishart ,  Huw D. Vater ,  William R. K. Esmieu ,  Cole Clissold ,  Wesley P. Blackaby

IPC: C07D413/14 ,  C07D471/08 ,  C07D498/08

Abstract: Provided are certain ATM kinase inhibitors of Formula I: Also provided herein are compositions of such compounds, and methods of their use.

公开(公告)号：US10106535B2

公开(公告)日：2018-10-23

申请号：US15482327

申请日：2017-04-07

Applicant: CHDI Foundation, Inc.

Inventor： Celia Dominguez ,  Ignacio Muñoz-Sanjuán ,  Michel Maillard ,  Christopher A. Luckhurst ,  Rebecca E. Jarvis ,  Roland W. Bürli ,  Daniel R. Allen ,  Alan F. Haughan ,  Perla Breccia ,  Huw D. Vater ,  Andrew J. Stott ,  Stephen D. Penrose ,  Michael Wall ,  Elizabeth A. Saville-Stones ,  Grant Wishart ,  Samantha J. Hughes

IPC: C07D471/04 ,  C07C259/08 ,  C07D277/64 ,  C07D231/12 ,  C07D231/56 ,  C07D261/20 ,  C07D241/12 ,  C07D239/26 ,  C07D213/61 ,  C07D333/60 ,  C07D275/04 ,  C07D213/64 ,  C07D277/62 ,  C07D241/42 ,  C07D213/56

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.

公开(公告)号：US20160031863A1

公开(公告)日：2016-02-04

申请号：US14776058

申请日：2014-03-10

Applicant: CHDI FOUNDATION, INC.

Inventor： Celia Dominguez ,  Ignacio Muñoz-Sanjuán ,  Michel Maillard ,  Huw D. Vater ,  Rebecca E. Jarvis ,  Christopher A. Luckhurst ,  Roland W. Bürli ,  Grant Wishart ,  Andrew J. Stott

IPC: C07D409/04 ,  C07D207/34 ,  C07D231/14 ,  C07D401/04 ,  C07D403/04

CPC classification number: C07D409/04 ,  C07D207/34 ,  C07D231/14 ,  C07D231/22 ,  C07D401/04 ,  C07D403/04

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.