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公开(公告)号：US10515715B1
公开(公告)日：2019-12-24
申请号：US16452214
申请日：2019-06-25
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
Abstract: A system, apparatus, and/or method is disclosed for determining a value of a property of a considered chemical composition. An identity of a sample chemical composition may be received. A sample chemical composition may comprise ingredients. Each of the ingredients may be associated with a value of a chemoinformatic property of chemoinformatic properties of the sample chemical composition. A value of a property of the sample chemical composition and at least one of (1) the identity of the sample chemical composition or (2) the values of the chemoinformatic properties of the ingredients of the sample chemical composition may be input into a model. The value of the property of the considered chemical composition may be determined, via the model, based on at least one of (1) an identity of the considered chemical composition or (2) values of chemoinformatic properties of ingredients of the considered chemical composition.
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公开(公告)号：US10118832B2
公开(公告)日：2018-11-06
申请号：US15272357
申请日：2016-09-21
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , John Vaughn , Long Pan
Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.
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公开(公告)号：US20170128330A1
公开(公告)日：2017-05-11
申请号：US15224681
申请日：2016-08-01
Applicant: Colgate-Palmolive Company
Inventor： John Vaughn , Iraklis Pappas , Long Pan
CPC classification number: A61K8/26 , A61K8/19 , A61K8/20 , A61K8/28 , A61K8/42 , A61K8/44 , A61K2800/58 , A61Q15/00 , C01F7/002 , C01F7/56 , C01P2002/86 , C01P2002/87
Abstract: An antiperspirant active composition comprising an aluminum salt, the aluminum salt (i) having an aluminum to chloride molar ratio of 0.3:1 to 3:1; and (ii) having a species of polyhydroxyoxoaluminum cation detectable at 76 ppm by 27Al NMR that is present in a relative abundance on a 27Al NMR spectrograph that is greater than any other polyhydroxyoxoaluminum cation detectable by 27Al NMR. Also, disclosed are methods of making the antiperspirant active.
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公开(公告)号：US09585825B2
公开(公告)日：2017-03-07
申请号：US14154216
申请日：2014-01-14
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Michael C. Fitzgerald , Long Pan
CPC classification number: A61K8/416 , A61K8/26 , A61K8/42 , A61K8/44 , A61K2800/31 , A61K2800/58 , A61Q15/00
Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier, and wherein the at least one antiperspirant active, the at least one basic compound and the at least one member chosen from a cation and zwitterion form a ternary eutectic system.
Abstract translation: 一种制备无水止汗组合物的方法，其包含（a）提供至少一种止汗剂活性物质（包括金属盐）的混合物和至少一种其中所述至少一种止汗活性剂溶解的止汗活性剂的无水载体，所述载体 包括至少一种选自碱性酰胺和碱性胺的碱性化合物和选自阳离子和两性离子的至少一种的共晶混合物; 和（b）加热所述混合物以形成所述至少一种止汗活性剂和所述无水载体的稳定的共晶体系，并且其中所述至少一种止汗活性剂，所述至少一种碱性化合物和至少一种选自阳离子 并且两性离子形成三元共晶体系。
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公开(公告)号：US20250057740A1
公开(公告)日：2025-02-20
申请号：US18917373
申请日：2024-10-16
Applicant: Colgate-Palmolive Company
Inventor： Carl MYERS , Iraklis Pappas , Zhigang Hao , Saide Tang
Abstract: Disclosed herein are high water oral care compositions comprising a stannous ion source. which compositions have improved stability. Methods of making and using the compositions are also provided.
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Patent Agency Ranking
公开(公告)号：US11315663B2
公开(公告)日：2022-04-26
申请号：US16949465
申请日：2020-10-30
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
Abstract: A system, apparatus, and/or method is disclosed for producing a personal care product. An identity of a considered chemical composition may be input into a model (e.g., a machine learning model). The identity of the considered chemical composition may include ingredients. Each of the ingredients of the considered chemical composition may be associated with a value of a chemoinformatic property of chemoinformatic properties of the considered chemical composition. A value of the property of the considered chemical composition may be determined via the model. The value may be based on the identity of the considered chemical composition. The property of the considered chemical composition may be affected by an interaction of at least two of the ingredients of the considered chemical composition. A personal care product comprised of the considered chemical composition may be produced.
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公开(公告)号：US10861588B1
公开(公告)日：2020-12-08
申请号：US16731533
申请日：2019-12-31
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
Abstract: A system, apparatus, and/or method is disclosed for producing a personal care product. Values of chemoinformatic properties of ingredients of a sample chemical composition are received. A value of a property of the sample chemical composition is received in which the property is affected by an interaction of at least two of the ingredients. The values of the chemoinformatic properties of the ingredients of the sample chemical composition and the value of the property of the sample chemical composition are input into a model. An identity of the considered chemical composition is determined, via the model, based on at least one of (1) values of chemoinformatic properties of ingredients of the considered chemical composition or (2) a value of a property of the considered chemical composition. The personal care product comprised of the considered chemical composition is produced.
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公开(公告)号：US20170008773A1
公开(公告)日：2017-01-12
申请号：US15272357
申请日：2016-09-21
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , John Vaughn , Long Pan
CPC classification number: C01F7/56 , A61K8/26 , A61K8/28 , A61K8/44 , A61K2800/592 , A61K2800/80 , A61Q15/00 , C01F7/002 , C01P2002/86 , C01P2002/87
Abstract: A composition comprising an aluminum chlorohydrate salt, the aluminum chlorohydrate salt having at least 50 mole % Al30 polyhydroxyoxoaluminum cation of all polyhydroxyoxoaluminum cations detectable by quantitative 27Al NMR within the aluminum chlorohydrate salt, and a buffer. The composition can optionally include zirconium. Also disclosed are a method of making an aluminum salt using an increased molar concentration of a starting aluminum salt with a buffer, a method of reducing perspiration with the aluminum chlorohydrate salt, and a method of treating water with the aluminum chlorohydrate salt.
Abstract translation: 一种包含氯化铝水合物盐的组合物，该水合氯化铝盐具有至少50摩尔％的所有聚羟基氧化铝阳离子的Al30聚羟基氧化铝阳离子，其可通过在水合氯化铝盐内的定量27Al NMR和缓冲液检测。 该组合物可以任选地包括锆。 还公开了使用起始铝盐与缓冲剂的摩尔浓度增加的方法，用氯化铝水合物盐减少汗水的方法以及用氯化铝水盐处理水的方法。
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公开(公告)号：US09539188B2
公开(公告)日：2017-01-10
申请号：US14807946
申请日：2015-07-24
Applicant: Colgate-Palmolive Company
Inventor： Iraklis Pappas , Long Pan
CPC classification number: C01F7/56 , A61K8/26 , A61K8/28 , A61K8/44 , A61K2800/592 , A61K2800/80 , A61Q15/00 , C01F7/002 , C01P2002/86 , C01P2002/87
Abstract: A method of making an antiperspirant active composition and the use of a heating step at elevated temperature to convert Al13 polyhydroxyoxoaluminum cations in the species detectable by 27Al NMR within an aqueous aluminum salt solution into Al30 polyhydroxyoxoaluminum cations in the species detectable by 27Al NMR without increasing a SEC Peak 3 area in the SEC chromatogram of the aluminum salt.
Abstract translation: 一种制备止汗活性组合物的方法和在升高的温度下使用加热步骤将AlI 3聚羟基氧化铝阳离子在AlAlO盐溶液中通过27Al NMR转化成可通过27Al NMR检测的物质中的Al30多羟基氧化铝阳离子，而不增加 SEC铝盐的SEC色谱图中的峰3区。
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公开(公告)号：US09526681B2
公开(公告)日：2016-12-27
申请号：US14649136
申请日：2012-12-03
Applicant: Colgate-Palmolive Company
Inventor： Ralph Peter Santarpia, III , Iraklis Pappas , Elizabeth Gittins
Abstract: Described herein are oral compositions comprising a basic amino acid, in free or salt form, and a sesquiterpene alcohol; and methods of making and using the same.
Abstract translation: 本文描述的是包含游离或盐形式的碱性氨基酸和倍半萜醇的口服组合物; 以及制作和使用它们的方法。
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