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公开(公告)号：US20230372211A1
公开(公告)日：2023-11-23
申请号：US18366067
申请日：2023-08-07
发明人： Shaoyi ZHANG , Saide Tang , Carl Myers , Guofeng Xu
摘要： This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号：US10532012B2
公开(公告)日：2020-01-14
申请号：US15680391
申请日：2017-08-18
发明人： Saide Tang , Lin Fei , Suman Chopra
IPC分类号： A61K8/25 , A61K8/34 , A61Q11/00 , A61K8/19 , A61K8/27 , A61K8/11 , B01J13/02 , B01J13/22 , B01J13/20
摘要： Methods for preparing high loading core shell silica (CSS) particles, or CSS particles having a relatively greater amount of surface active silicate groups than CSS particles prepared according to conventional methods is provided. The method may include contacting silica particles with a base having a first metal ion to produce core shell silica particles. Each of the core shell silica particles may include a silica core and a silicate of the first metal ion etched on a surface of the silica core. The method may also include contacting each of the core shell silica particles having the silicate of the first metal ion with an acidic aqueous solution including a metal salt having a second metal ion to produce core shell silica particles including the silica core and a silicate of the second metal ion on the surface of the silica core.
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公开(公告)号：US11890362B2
公开(公告)日：2024-02-06
申请号：US16851291
申请日：2020-04-17
发明人： Saide Tang , Lin Fei , Suman Chopra , Hallena Strotman , Pooja Kulkarni
CPC分类号： A61K8/25 , A61K8/042 , A61Q11/00 , A61K2800/651
摘要： Described herein are oral care compositions comprising metal silicates (e.g. sodium silicate); along with methods of making and using same.
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公开(公告)号：US11723846B2
公开(公告)日：2023-08-15
申请号：US17248200
申请日：2021-01-14
发明人： Shaoyi Zhang , Saide Tang , Carl Myers , Guofeng Xu
摘要： This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号：US11819561B2
公开(公告)日：2023-11-21
申请号：US17359026
申请日：2021-06-25
发明人： Ningwei Li , Hongwei Shen , Saide Tang , Betty Won , Viktor Dubovoy , Long Pan
CPC分类号： A61K8/43 , A61K8/24 , A61Q11/00 , A61K2800/28 , A61K2800/48 , A61K2800/524 , A61K2800/5422 , A61K2800/5426 , A61K2800/5428 , A61K2800/74
摘要： This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, in particular, chlorhexidine and polyphosphate salts, by formulating the composition with a surfactant.
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公开(公告)号：US11806411B2
公开(公告)日：2023-11-07
申请号：US16828326
申请日：2020-03-24
发明人： Pooja Kulkarni , Lin Fei , Suman Chopra , Hallena Strotman , Saide Tang
IPC分类号： A61K8/02 , A61K8/19 , A61K8/25 , A61K8/27 , A61Q11/00 , C03C15/00 , C03C17/22 , C09C1/30 , C09C3/06
CPC分类号： A61K8/0245 , A61K8/0216 , A61K8/19 , A61K8/25 , A61K8/27 , A61Q11/00 , A61K2800/28 , A61K2800/413 , A61K2800/621 , A61K2800/651 , A61K2800/92 , C03C15/00 , C03C17/22 , C09C1/3054 , C09C3/063
摘要： Described herein are oral care compositions comprising metal silicates (e.g. potassium silicate); along with methods of making and using same.
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公开(公告)号：US20210137803A1
公开(公告)日：2021-05-13
申请号：US17248200
申请日：2021-01-14
发明人： Shaoyi Zhang , Saide Tang , Carl Myers , Guofeng Xu
摘要： This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号：US10918580B2
公开(公告)日：2021-02-16
申请号：US16840857
申请日：2020-04-06
发明人： Shaoyi Zhang , Saide Tang , Carl Myers , Guofeng Xu
摘要： This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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