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公开(公告)号：US10857083B2
公开(公告)日：2020-12-08
申请号：US16216533
申请日：2018-12-11
发明人： Long Pan , Donghui Wu , Ravi Subramanyam , Hongwei Shen , Chi-Yuan Cheng , Tatiana Brinzari
IPC分类号： A61K8/44 , A61Q11/00 , C07C271/06 , C07C279/14 , C07C269/04 , A61K31/4172 , A61K8/21 , A61K33/16 , A61K31/198 , A61K8/49 , A61K8/19
摘要： Disclosed herein are amino acid carbamate complexes, methods of synthesis thereof, oral care compositions comprising the same, and methods of making and using thereof.
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公开(公告)号：US10299578B2
公开(公告)日：2019-05-28
申请号：US15309192
申请日：2014-05-07
发明人： Donghui Wu , Alan Sorrentino , Robert Moskovich , Eduardo Jimenez , Kenneth Waguespack , Douglas Joseph Hohlbein , Matthew Lee Kolb , Paul Donald Carse
摘要： Disclosed is an oral care implement, comprising: a body comprising a handle and a head at an end of the handle; the body having a cavity therein for storing an oral care fluid; the head having at least one oral care element extending therefrom, and a fluid outlet through which the oral care fluid is dispensable to an exterior of the oral care implement; a passageway fluidly connecting the cavity with the fluid outlet; a mechanism for introducing air into the cavity from the exterior of the oral care implement; and a control valve on the head movable relative to the head between a first position for preventing fluid flow from the cavity through the fluid outlet and a second position for permitting fluid flow from the cavity through the fluid outlet.
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公开(公告)号：US20140065081A1
公开(公告)日：2014-03-06
申请号：US14033859
申请日：2013-09-23
发明人： Daniel W. Smith , Amjad Farooq , Donghui Wu , Marija Heibel , Karen Drehs
CPC分类号： C11B9/0007 , A61K8/42 , A61K8/925 , A61K2800/57 , A61Q11/00 , A61Q13/00 , C11B9/0003 , C11B9/0061 , C11D3/50 , C11D3/507
摘要： The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precursors. Further the invention relates to compositions, comprising the precursor of the invention.
摘要翻译： 本发明涉及一类包含一种或多种衍生自X-OH和醛或酮的反应的化合物的香料前体化合物，所述香料前体化合物具有式XOC（R）（R *）（OR **）其中R是C6-24烷基，C6-24芳烷基或C6-24烷芳基; R *是H或C6-24烷基，C6-24芳烷基或C6-24烷芳基; R **是H或X; X-O表示衍生自X-OH的部分，并且其中X-OH是选自表面活性剂，织物柔软剂，软化剂前体酯胺，软化剂前体酰胺胺，头发调理剂，皮肤条件，糖和聚合物的化合物。 在第二方面，本发明涉及一种制备这种前体的方法。 本发明还涉及包含本发明前体的组合物。
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公开(公告)号：US20140056825A1
公开(公告)日：2014-02-27
申请号：US14033879
申请日：2013-09-23
发明人： Daniel W. Smith , Amjad Farooq , Donghui Wu , Marija Heibel , Karen Drehs
CPC分类号： C11B9/0007 , A61K8/42 , A61K8/925 , A61K2800/57 , A61Q11/00 , A61Q13/00 , C11B9/0003 , C11B9/0061 , C11D3/50 , C11D3/507
摘要： The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, said fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precusors. Further the invention relates to compositions, comprising the precursor of the invention.
摘要翻译： 本发明涉及一类包含一种或多种衍生自X-OH和醛或酮的反应的化合物的香料前体化合物，所述香料前体化合物具有式XOC（R）（R *）（OR **）其中R是C6-24烷基，C6-24芳烷基或C6-24烷芳基; R *是H或C6-24烷基，C6-24芳烷基或C6-24烷芳基; R **是H或X; X-O表示衍生自X-OH的部分，并且其中X-OH是选自表面活性剂，织物柔软剂，软化剂前体酯胺，软化剂前体酰胺胺，头发调理剂，皮肤条件，糖和聚合物的化合物。 在第二方面，本发明涉及一种制备这种预处理剂的方法。 本发明还涉及包含本发明前体的组合物。
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公开(公告)号：US11315663B2
公开(公告)日：2022-04-26
申请号：US16949465
申请日：2020-10-30
发明人： Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
摘要： A system, apparatus, and/or method is disclosed for producing a personal care product. An identity of a considered chemical composition may be input into a model (e.g., a machine learning model). The identity of the considered chemical composition may include ingredients. Each of the ingredients of the considered chemical composition may be associated with a value of a chemoinformatic property of chemoinformatic properties of the considered chemical composition. A value of the property of the considered chemical composition may be determined via the model. The value may be based on the identity of the considered chemical composition. The property of the considered chemical composition may be affected by an interaction of at least two of the ingredients of the considered chemical composition. A personal care product comprised of the considered chemical composition may be produced.
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公开(公告)号：US10861588B1
公开(公告)日：2020-12-08
申请号：US16731533
申请日：2019-12-31
发明人： Iraklis Pappas , Bartosz Luczynski , Donghui Wu , Dong Hyun Kim
摘要： A system, apparatus, and/or method is disclosed for producing a personal care product. Values of chemoinformatic properties of ingredients of a sample chemical composition are received. A value of a property of the sample chemical composition is received in which the property is affected by an interaction of at least two of the ingredients. The values of the chemoinformatic properties of the ingredients of the sample chemical composition and the value of the property of the sample chemical composition are input into a model. An identity of the considered chemical composition is determined, via the model, based on at least one of (1) values of chemoinformatic properties of ingredients of the considered chemical composition or (2) a value of a property of the considered chemical composition. The personal care product comprised of the considered chemical composition is produced.
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公开(公告)号：US10548829B2
公开(公告)日：2020-02-04
申请号：US16266661
申请日：2019-02-04
发明人： Jane Ong , James Masters , Tatiana Brinzari , Chi-Yuan Cheng , Donghui Wu , Long Pan
摘要： Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
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公开(公告)号：US10278487B2
公开(公告)日：2019-05-07
申请号：US15309187
申请日：2014-05-07
发明人： Donghui Wu , Alan Sorrentino , Robert Moskovich , Eduardo Jimenez , Kenneth Waguespack , Douglas Joseph Hohlbein , Matthew Lee Kolb , Paul Donald Carse
摘要： An oral care implement having a body comprising a handle, a head having at least one oral care element extending therefrom, and at least one fluid outlet; a reservoir in the body and for storing an oral care fluid; and a pump in the body for pumping the oral care fluid from the reservoir towards the fluid outlet, wherein the pump is an umbrella check valve circumferentially surrounding a duckbill check valve. Alternatively, the invention is a method of manufacturing an oral care implement, including the steps of providing a body comprising a base having first and second holes extending therethrough; and fitting to the body a unitary component comprising first and second valves at a position at which the first valve blocks the first hole and the second valve blocks the second hole, wherein the first valve is an umbrella check valve that circumferentially surrounds the second valve.
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公开(公告)号：US20150265041A1
公开(公告)日：2015-09-24
申请号：US14434320
申请日：2012-10-18
发明人： Christine Boyke , Donghui Wu
CPC分类号： A46B11/001 , A46B5/0041 , A46B5/0075 , A46B15/0095 , A46B2200/1066
摘要： An oral care system including an elongated member having tooth cleaning elements and a store of oral care material. In one aspect, the invention can be a toothbrush comprising a handle; a through-slot extending through the handle; an elongated member rotatably coupled to the housing for rotation about a rotational axis, the elongated member comprising: a toothbrush head located on a first side of the rotational axis; and a dispenser comprising a store of oral care material located on a second side of the rotational axis; a plurality of tooth cleaning elements extending from the toothbrush head; the elongated member rotatable about the rotational axis between: (1) a first state in which the toothbrush head protrudes from the handle while the dispenser is nested within the through-slot; and (2) a second state in which the dispenser protrudes from the housing while the toothbrush head is nested within the through-slot.
摘要翻译： 一种口腔护理系统，包括具有牙齿清洁元件的细长构件和口腔护理材料储存器。 一方面，本发明可以是包括手柄的牙刷; 延伸穿过手柄的通孔; 细长构件，其可旋转地联接到所述壳体以用于围绕旋转轴线旋转，所述细长构件包括：位于所述旋转轴线的第一侧上的牙刷头部; 以及分配器，其包括位于所述旋转轴线的第二侧上的口腔护理材料储存器; 从牙刷头延伸的多个牙齿清洁元件; 所述细长构件可以围绕所述旋转轴线旋转：（1）当所述分配器嵌套在所述通孔内时，所述牙刷头从所述手柄突出的第一状态; 和（2）第二状态，其中分配器从壳体突出，同时牙刷头嵌套在通孔内。
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公开(公告)号：US08906843B2
公开(公告)日：2014-12-09
申请号：US14034453
申请日：2013-09-23
发明人： Daniel W. Smith , Amjad Farooq , Donghui Wu , Marija Heibel , Karen Drehs
CPC分类号： C11B9/0007 , A61K8/42 , A61K8/925 , A61K2800/57 , A61Q11/00 , A61Q13/00 , C11B9/0003 , C11B9/0061 , C11D3/50 , C11D3/507
摘要： The present invention relates to a class of fragrance precursor compounds comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, the fragrance precursor compounds being of the formula X—O—C(R)(R*)(OR**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is H or X; X—O representing a moiety derived from X—OH, and wherein X—OH is a compound selected from the group consisting of surfactants, fabric softeners, softener precursor ester amines, softener precursor amido amines, hair conditioners, skin conditions, saccharides and polymers. In a second aspect it relates to a method of preparing such precursors. Further the invention relates to compositions, comprising the precursor of the invention.
摘要翻译： 本发明涉及一类香料前体化合物，其包含一种或多种衍生自X-OH和醛或酮的反应的化合物，所述香料前体化合物具有式X-O-C（R）（R *）（OR **）其中R是C6-24烷基，C6-24芳烷基或C6-24烷芳基; R *是H或C6-24烷基，C6-24芳烷基或C6-24烷芳基; R **是H或X; X-O代表衍生自X-OH的部分，其中X-OH是选自表面活性剂，织物软化剂，软化剂前体酯胺，软化剂前体酰胺胺，头发调理剂，皮肤条件，糖和聚合物的化合物 。 在第二方面，本发明涉及一种制备这种前体的方法。 本发明还涉及包含本发明前体的组合物。
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