Oral Biofilm Models and Uses Thereof
    14.
    发明申请

    公开(公告)号:US20170247741A1

    公开(公告)日:2017-08-31

    申请号:US15512125

    申请日:2014-10-06

    CPC classification number: C12Q1/18 C12N1/20 G01N1/2806

    Abstract: The present disclosure provides an oral biofilm model including a substrate including a first surface, a second surface, and a plurality of specimens fixedly attached to the first surface, wherein an oral biofilm is capable of forming on the specimen. The surface roughness of at least one of the specimens of the plurality is less than or greater than a surface roughness of at least a second specimen of the plurality. The oral biofilm model also includes a body having sides and a bottom defining a vessel. The body is adapted to receive the substrate and the plurality of specimens and is further adapted to receive a fluid. Methods of forming oral biofilms and methods for identifying an agent for reducing or inhibiting biofilm formation are also provided.

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