公开(公告)号：US09750670B2

公开(公告)日：2017-09-05

申请号：US14650898

申请日：2013-11-07

Applicant: Colgate-Palmolive Company

Inventor： Long Pan ,  Shaotang Yuan ,  Shiri Nawrocki

IPC: A61K8/44 ,  A61K8/27 ,  A61Q15/00 ,  A61Q19/10 ,  A61Q19/00 ,  A61Q11/00 ,  A61Q17/00

CPC classification number: A61K8/27 ,  A61K8/44 ,  A61K8/442 ,  A61K8/447 ,  A61K2800/58 ,  A61K2800/5922 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/10

Abstract: Provided are compositions, e.g., oral and personal care products, comprising (i) a tetrabasic zinc-amino acid or trialkyl glycine-halide complex, and (ii) cysteine in free or in orally or cosmetically acceptable salt form, together with methods of making and using the same.

公开(公告)号：US20170189285A1

公开(公告)日：2017-07-06

申请号：US15391830

申请日：2016-12-27

Applicant: Colgate-Palmolive Company

Inventor： Daniel Schankel ,  Shiri Nawrocki ,  Viktor Dubovoy ,  Long Pan

IPC: A61K8/21 ,  A61K8/24 ,  A61Q15/00

CPC classification number: A61K8/21 ,  A61K8/19 ,  A61K8/24 ,  A61K2800/30 ,  A61K2800/58 ,  A61Q15/00

Abstract: Described herein, are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride and a pyrophosphate salt. Also described are external personal care compositions comprising the complexes, and uses thereof.

公开(公告)号：US20210259936A1

公开(公告)日：2021-08-26

申请号：US17302509

申请日：2021-05-05

Applicant: Colgate-Palmolive Company

Inventor： Baohua Qiao ,  Peter R. Hilliard, JR. ,  Long Pan ,  Shiri Nawrocki ,  Viktor Dubovoy

IPC: A61K8/27 ,  A61Q15/00 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/55 ,  A61K8/64

Abstract: A personal care composition, comprising a soluble zinc polyphosphate complex made by combining ingredients comprising an organic zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and an aqueous solvent; wherein the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Also, a method of using the composition for reducing at least one of perspiration or body odor.

公开(公告)号：US20190167546A1

公开(公告)日：2019-06-06

申请号：US16267424

申请日：2019-02-05

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Viktor DUBOVOY ,  Long PAN ,  Zhigang HAO ,  Nihal DOGU

IPC: A61K8/24 ,  A61Q11/00 ,  A61K8/19

Abstract: Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and oral care compositions comprising the complex and uses thereof.

公开(公告)号：US20170360664A1

公开(公告)日：2017-12-21

申请号：US15393178

申请日：2016-12-28

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Viktor Dubovoy ,  Long Pan

IPC: A61K8/24 ,  A61Q15/00 ,  A61K8/20 ,  A61K8/21

CPC classification number: A61K8/24 ,  A61K8/19 ,  A61K8/20 ,  A61K8/21 ,  A61K2800/30 ,  A61K2800/52 ,  A61K2800/874 ,  A61Q15/00

Abstract: Described herein, are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride or tin (II) chloride and a tripolyphosphate salt, e.g., sodium tripolyphosphate (Na5P3O10), and external personal care compositions comprising the complexes, and uses thereof.

公开(公告)号：US20170121351A1

公开(公告)日：2017-05-04

申请号：US15319756

申请日：2014-06-18

Applicant: Colgate-Palmolive Company

Inventor： Shiri Nawrocki ,  Ravi SUBRAMANYAM ,  Long PAN

IPC: C07F3/06

CPC classification number: C07F3/06 ,  C07B2200/13 ,  C07F3/003

Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl−, in which zinc chloride is reacted with lysine, in aqueous solution. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

公开(公告)号：US20150313827A1

公开(公告)日：2015-11-05

申请号：US14650952

申请日：2013-11-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Eugene Hardy ,  Long Pan ,  Shiri Nawrocki ,  Evangelia Arvanitidou ,  Laurence D. Du-Thumm

IPC: A61K8/58 ,  A61Q19/10 ,  A61Q15/00 ,  A01N55/02 ,  A61Q17/04

CPC classification number: A01N59/16 ,  A01N55/02 ,  A61K8/20 ,  A61K8/27 ,  A61K8/44 ,  A61K8/58 ,  A61K2800/58 ,  A61K2800/592 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/10 ,  A01N25/04 ,  A01N37/44

Abstract: Provided is a personal cleansing composition for application to the skin which comprises a zinc X halide present in an amount to provide at least 0.36 weight % of the composition of zinc, and a surfactant, wherein X is an amino acid or trimethylglycine. Methods of making and using the compositions are also provided. The zinc X halide is can be used to deliver zinc salts to reduce or prevent sunburn, kill bacteria, or reduce perspiration.

Abstract translation: 提供一种用于皮肤的个人清洁组合物，其包含以提供组合物的至少0.36重量％的量的锌X卤化物和表面活性剂，其中X是氨基酸或三甲基甘氨酸。 还提供了制备和使用组合物的方法。 锌X卤化物可用于递送锌盐以减少或防止晒伤，杀死细菌或减少汗水。