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    NOVEL COMPOUNDS
    11.
    发明申请
    NOVEL COMPOUNDS 审中-公开
    新型化合物

    公开(公告)号：US20080058391A1

    公开(公告)日：2008-03-06

    申请号：US11835522

    申请日：2007-08-08

    Applicant: Christopher Johnson ,  David MacPherson ,  Giancarlo Trani

    Inventor： Christopher Johnson ,  David MacPherson ,  Giancarlo Trani

    IPC: A61K31/44 ,  A61P1/00 ,  A61P25/00 ,  C07D213/02

    CPC classification number: C07D213/38

    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof: wherein; each of R1 to R4 is independently selected from hydrogen and C1-4 alkyl and each of rings A and B independently is optionally further substituted by up to three substituents, each of which is independently selected from the group consisting of halogen, hydroxy, C1-4alkoxy, C1-4alkyl, C1-5alkanoyl, CF3, CF3O and cyano; with the proviso that ring A must contain at least one CF3 group, are useful in the treatment of diseases and conditions mediated by modulation of use-dependent voltage-gated sodium channels.

    Abstract translation: 式（I）化合物及其药学上可接受的盐：其中; R 1至R 4中的每一个独立地选自氢和C 1-4 - 烷基，环A和B各自独立地任选地进一步 被至多三个取代基取代，每个取代基独立地选自卤素，羟基，C 1-4烷氧基，C 1-4烷基，C 1-4烷基， 烷基，CF 3，CF 3 O和氰基; 条件是环A必须含有至少一个CF 3 3基团，可用于治疗由依赖于用途的电压门控钠通道调节介导的疾病和病症。

    Selectable clock unit
    12.
    发明申请
    Selectable clock unit 审中-公开
    可选择的时钟单元

    公开(公告)号：US20070189106A1

    公开(公告)日：2007-08-16

    申请号：US11648903

    申请日：2007-01-03

    Applicant: Christopher Johnson ,  Scott Schaefer

    Inventor： Christopher Johnson ,  Scott Schaefer

    IPC: G11C8/00

    CPC classification number: G11C7/225 ,  G11C7/1045 ,  G11C7/22 ,  G11C8/18 ,  G11C2207/2227

    Abstract: The present invention provides a memory device having a mode register with a selectable bit which sets the memory device to operate with a selected one of a plurality of possible clock input signals, for example, a single clock input or differential clock input.

    Abstract translation: 本发明提供一种存储器件，其具有具有可选位的模式寄存器，该可选位将存储器件设置为使用多个可能的时钟输入信号（例如单个时钟输入或差分时钟输入）中选定的一个进行操作。

    SYSTEM AND METHOD FOR CLINICAL PROCESS DECISIONING
    13.
    发明申请
    SYSTEM AND METHOD FOR CLINICAL PROCESS DECISIONING 审中-公开
    用于临床过程决策的系统和方法

    公开(公告)号：US20070112610A1

    公开(公告)日：2007-05-17

    申请号：US11559045

    申请日：2006-11-13

    Applicant: Christopher Johnson ,  Kunter Akbay ,  Sung-Ho Ahn ,  Abha Moitra ,  Onur Dulgeroglu

    Inventor： Christopher Johnson ,  Kunter Akbay ,  Sung-Ho Ahn ,  Abha Moitra ,  Onur Dulgeroglu

    IPC: G06F9/46

    CPC classification number: G06Q50/22 ,  G06Q10/04 ,  G06Q10/06 ,  G06Q10/0631

    Abstract: A system and method for use in planning procedures subject to variation is provided comprising the following components: a duration estimator module configured to characterize average duration times and variations from average for a given procedure or activity; a block allocation planner module configured to schedule procedures or activities in accordance with characterized times from the duration estimator module; and a user interface module configured to permit a user to visualize variation, to visualize scheduling opportunities and constraints and to view information output for use in scheduling procedures and activities.

    Abstract translation: 提供了一种用于在变化中的规划过程中使用的系统和方法，包括以下部件：持续时间估计器模块，其被配置为表征给定过程或活动的平均持续时间和平均值的变化; 块分配计划器模块，被配置为根据来自持续时间估计器模块的特征时间调度过程或活动; 以及用户界面模块，其被配置为允许用户可视化变化，可视化调度机会和约束，以及查看用于调度过程和活动的信息输出。

    IMPROVED PROCESS FOR ANALYZING FOR SEPARATING, AND FOR ISOLATING POLAR PROTIC MONOMERS AND/OR OLIGOMERS
    14.
    发明申请
    IMPROVED PROCESS FOR ANALYZING FOR SEPARATING, AND FOR ISOLATING POLAR PROTIC MONOMERS AND/OR OLIGOMERS 有权
    用于分离和分离极性运动单体和/或低聚物的改进方法

    公开(公告)号：US20070075020A1

    公开(公告)日：2007-04-05

    申请号：US11242210

    申请日：2005-10-03

    Applicant: Mark Kelm ,  Christopher Johnson ,  Rebecca Robbins

    Inventor： Mark Kelm ,  Christopher Johnson ,  Rebecca Robbins

    IPC: B01D15/08

    CPC classification number: B01D15/32 ,  B01J20/286 ,  B01J20/288 ,  B01J2220/54

    Abstract: An improved process for separating and isolating individual polar protic monomer(s) and/or oligomer(s) on the basis of degree of polymerization. A liquid sample containing polar protic monomer(s) and/or oligomer(s) is introduced into a liquid chromatography (LC) column packed with a polar bonded stationary chromatographic phase. The individual polar protic monomer(s) and/or oligomer(s) are separated via a binary mobile phase elution. One or more individual fractions containing the monomer(s) and/or oligomer(s) are eluted. The polar protic monomer(s) and/or oligomer(s) may be proanthocyanidins, hydrolyzable tannins, oligosaccharides, oligonucleotides, peptides, acrylamides, polysorbates, polyketides, poloxamers, polyethylene glycols, polyoxyethylene alcohols or polyvinyl alcohols. The binary mobile phase comprises an A phase consisting essentially of a polar aprotic solvent and a B phase consisting essentially of a polar protic solvent. A process for separating and isolating xanthine(s) (e.g., caffeine and theobromine) from polar protic monomer(s) and/or oligomer(s). A liquid sample containing xanthine(s) and polar protic monomer(s) and/or oligomer(s) is introduced into an LC column packed with a polar bonded stationary chromatographic phase. The xanthines are separated via an isocratic mobile phase elution, and one or more individual fractions containing the xanthines are eluted.

    Abstract translation: 基于聚合度分离和分离各极性质子单体和/或低聚物的改进方法。 将含有极性质子单体和/或低聚物的液体样品引入填充有极性键合静止色谱相的液相色谱（LC）柱中。 单独的极性质子单体和/或低聚物通过二元流动相洗脱分离。 洗脱含有单体和/或低聚物的一种或多种单独级分。 极性质子单体和/或低聚物可以是原花青素，可水解单宁，寡糖，寡核苷酸，肽，丙烯酰胺，聚山梨酯，聚酮化合物，泊洛沙姆，聚乙二醇，聚氧乙烯醇或聚乙烯醇。 二元流动相包含基本上由极性非质子溶剂和基本上由极性质子溶剂组成的B相组成的A相。 从极性质子单体和/或低聚物分离和分离黄嘌呤（例如咖啡因和可可碱）的方法。 将含有黄嘌呤和极性质子单体和/或低聚物的液体样品引入填充有极性键合的静止色谱相的LC柱中。 黄嘌呤通过等度流动相洗脱分离，并且洗脱含有黄嘌呤的一个或多个单独级分。

    Sub-malleolar non-articulating prosthetic foot with improved dorsiflexion
    15.
    发明申请
    Sub-malleolar non-articulating prosthetic foot with improved dorsiflexion 审中-公开
    具有改善背屈功能的亚踝非关节假肢足

    公开(公告)号：US20060167563A1

    公开(公告)日：2006-07-27

    申请号：US11338995

    申请日：2006-01-25

    Applicant: Christopher Johnson ,  Aaron Taszreak

    Inventor： Christopher Johnson ,  Aaron Taszreak

    IPC: A61F2/66

    CPC classification number: A61F2/66 ,  A61F2/6607 ,  A61F2002/30359 ,  A61F2002/3051 ,  A61F2002/5003 ,  A61F2002/5007 ,  A61F2002/5055 ,  A61F2002/6621 ,  A61F2002/665 ,  A61F2220/0025 ,  A61F2220/0033

    Abstract: A prosthetic foot includes a sole plate having a body formed of resilient material. The sole plate is elongated along an anterior and posterior axis wherein an anterior portion of the plate defines a toe portion and the posterior portion defines a heel portion. An ankle member having a planar portion in contact with the sole plate is rigidly affixed to the sole plate at the heel portion. The ankle member has an extension portion positioned anterior of the planar portion and separated from the planar portion by a transition portion. A resilient pad is disposed between the contact portion of the ankle member and the sole plate. The resilient pad and extension portion of ankle member define a gap such that as a user's weight is transferred anterior following initial contact, the extension portion of the ankle member tilts forward reducing the gap formed between the resilient pad and the extension portion for improving the dorsiflexion of the prosthetic foot.

    Abstract translation: 假脚包括具有由弹性材料形成的主体的底板。 鞋底板沿着前后轴线是细长的，其中板的前部限定脚趾部分，并且后部限定鞋跟部分。 具有与鞋底板接触的平面部分的脚踝构件在脚跟部分处刚性地固定到鞋底板。 踝构件具有位于平面部分前方的延伸部分，并且通过过渡部分与平面部分分离。 弹性垫设置在踝构件的接触部分和底板之间。 踝构件的弹性垫和延伸部限定了间隙，使得当初次接触之后使用者的重量向前移动时，踝构件的延伸部分向前倾斜，减少弹性垫和延伸部之间形成的间隙，以改善背屈 的假脚。

    Method for the use of and interaction with business system transfer functions
    16.
    发明申请
    Method for the use of and interaction with business system transfer functions 审中-公开
    使用和与业务系统传输功能相互作用的方法

    公开(公告)号：US20060111931A1

    公开(公告)日：2006-05-25

    申请号：US11321828

    申请日：2005-12-29

    Applicant: Christopher Johnson ,  Onur Dulgeroglu ,  Peter Kalish ,  Kunter Akbay

    Inventor： Christopher Johnson ,  Onur Dulgeroglu ,  Peter Kalish ,  Kunter Akbay

    IPC: G06Q99/00 ,  G05B19/418 ,  G06F15/02 ,  G07G1/00

    CPC classification number: G06Q10/10 ,  G06Q10/063 ,  G06Q10/067

    Abstract: A method for using and interacting with mathematical or algorithmic business system transfer functions in support of a business information, analysis, decisioning and control system. The method includes developing at least one high-level business system view wherein the transfer function is configured to quantitatively express the business system view; identifying a number of input parameters associated with one or more of the resources used in the business process, identifying at least one output parameter associated with the operation of the business process; collecting operational data that associate the number of input parameters with the at least one output parameter based on an actual operation of the business process. The method also includes a primary display layer that presents a control scenario for a testbed environment for the business information and decisioning control system.

    Abstract translation: 一种使用和与数学或算法业务系统传输功能进行交互的方法，以支持业务信息，分析，决策和控制系统。 该方法包括开发至少一个高级业务系统视图，其中传送功能被配置为定量地表达业务系统视图; 识别与业务过程中使用的一种或多种资源相关联的输入参数的数量，识别与业务过程的操作相关联的至少一个输出参数; 收集基于所述业务过程的实际操作将所述输入参数的数量与所述至少一个输出参数相关联的操作数据。 该方法还包括主显示层，其为业务信息和决策控制系统的测试台环境呈现控制场景。

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