公开(公告)号：US20180352842A1

公开(公告)日：2018-12-13

申请号：US15756626

申请日：2016-09-09

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Andrea BULBARELLO ,  Kevin PRUDENCE ,  Loni SCHWEIKERT ,  Kai URBAN

IPC: A23L33/105 ,  A61K36/185 ,  A61K9/16

CPC classification number: A23L33/105 ,  A23L5/00 ,  A23L27/70 ,  A23L27/84 ,  A23P10/40 ,  A23V2002/00 ,  A61K9/1617 ,  A61K36/185 ,  A61K36/736 ,  A61K2236/00

Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise therapeutically active or nutritious plant extracts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

公开(公告)号：US20210045427A1

公开(公告)日：2021-02-18

申请号：US16977303

申请日：2019-03-14

Applicant: DSM IP ASSETS B.V.

Inventor： Jihane ACHKAR ,  Alan CONNOLLY ,  Kai URBAN

IPC: A23P30/20 ,  A23L33/15 ,  A23L7/10

Abstract: The present invention relates to extrudates comprising water-soluble vitamins and other micronutrients. They are obtainable by adiabatic extrusion. During extrusion, temperature is controlled by the viscosity of the composition which is being extruded. Pasteurization temperature is reached, i.e. the extrudates of the invention meet the requirements set out in microbiological guidelines.

公开(公告)号：US20190098924A1

公开(公告)日：2019-04-04

申请号：US16086433

申请日：2017-04-03

Applicant: DSM IP Assets B.V.

Inventor： Antonio ESTRELLA ,  Elger FUNDA ,  Zdravka MISIC ,  Christian SCHAEFER ,  Markus Ivo BECK ,  Bernd SCHLEGEL ,  Kai URBAN

IPC: A23L33/105 ,  A23L33/125 ,  A23L29/212 ,  A23P10/28

Abstract: The present invention is directed towards a solid formulation comprising a milled carotenoid, at least one hydrocolloid, a glucose syrup, sucrose and at least one water-soluble antioxidant (preferably sodium ascorbate), wherein the carotenoid is selected from the group consisting of lutein and zeaxanthin and any mixture thereof, wherein the hydrocolloid is selected from the group consisting of modified food starches and any mixtures thereof, and wherein the milled carotenoid has the following particle size distribution: D [3, 2] in the range of from 0.6 to 1.5 μm and D [v, 0.5] in the range of from 1.1 to 3.5 μm, all D values as measured by laser diffraction (Malvern Instruments Ltd, Malvern, UK, Mastersizer 3000) according to the Fraunhofer scattering model. This solid formulation is in form of granules which are used for dietary supplements and pharmaceuticals, such as e.g. multi-vitamin and/or multi-mineral tablets. Surprisingly these tablets show a low compression loss.

公开(公告)号：US20180289624A1

公开(公告)日：2018-10-11

申请号：US15756619

申请日：2016-09-09

Applicant: DSM IP Assets B.V.

Inventor： Markus BECK ,  Andrea BULBARELLO ,  Kevin PRUDENCE ,  Loni SCHWEIKERT ,  Kai URBAN

IPC: A61K9/16 ,  A61K33/26 ,  A23L33/16

Abstract: This invention relates to a process for producing solid formulations. These solid formulations comprise physiologically active inorganic metal salts, which are known for being bad-tasting. These new solid formulation are neutral in taste. Furthermore the present invention relate to these solid formulations as well as to their use in the production of food, feed, nutritional supplement and personal care products.

公开(公告)号：US20160263128A1

公开(公告)日：2016-09-15

申请号：US15165366

申请日：2016-05-26

Applicant: DSM IP ASSETS B.V.

Inventor： Neil Robert BUCK ,  Wouter CLAERHOUT ,  Bruno H. LEUENBERGER ,  Elisabeth STOECKLIN ,  Kai URBAN ,  Swen WOLFRAM

IPC: A61K31/593

CPC classification number: A61K31/593 ,  A23L33/155 ,  A23V2002/00 ,  A61K31/59 ,  Y02A50/469 ,  A23V2200/316 ,  A23V2250/7106 ,  A61K2300/00

Abstract: We disclose the use of 25-OH D3 (calcifediol) to increase muscle strength, muscle function, or both. Vitamin D3 (cholecalciferol) may optionally be used together with 25-OH D3. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.

Abstract translation: 我们公开了使用25-OH D3（calcifediol）来增加肌肉力量，肌肉功能或两者。 维生素D3（胆钙化醇）可以任选地与25-OH D3一起使用。 还公开了药物组合物的形式和剂量，以及制备药物的方法。