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公开(公告)号：US07798789B2
公开(公告)日：2010-09-21
申请号：US11749460
申请日：2007-05-16
CPC分类号： A61M5/14216 , A61M5/14276 , A61M2205/103 , A61M2205/106 , F04B17/048
摘要： The present invention relates to a method and related apparatus for rotating a piston of a drug pump during the pumping stroke to reduce drug pump wear. The actuator may move a piston that pumps fluid through a pumping channel. In the present invention, the armature includes one or more openings or shapes that cause the actuator, including the armature and the piston, to rotate about a longitudinal axis of the piston during the pumping stroke. Rotation of the actuator member may help to reduce wear to the actuator member and the pump itself caused by repetitive pumping motions.
摘要翻译： 本发明涉及一种用于在泵送冲程期间旋转药泵的活塞以减少药泵磨损的方法和相关装置。 致动器可以移动通过泵送通道泵送流体的活塞。 在本发明中，电枢包括一个或多个开口或形状，其使包括电枢和活塞在内的致动器在泵送冲程期间围绕活塞的纵向轴线旋转。 致动器构件的旋转可以有助于减少由重复泵送运动引起的致动器构件和泵本身的磨损。
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公开(公告)号：US20100152714A1
公开(公告)日：2010-06-17
申请号：US12684436
申请日：2010-01-08
IPC分类号： A61M31/00
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/165 , A61M5/36 , A61M2205/7518 , F04B17/042 , F04B19/006 , F04B35/045 , F04B53/008 , F04B53/1032
摘要： An implantable infusion device includes a reservoir for housing an infusion medium and a drive mechanism having an inlet chamber, a piston and a piston channel. The inlet chamber is in fluid communication with the reservoir. The piston channel is in fluid communication with the inlet chamber, and has a distal end and a proximal end, the proximal end being closer to the inlet channel than the distal end. The piston is axially moveable within the piston channel to drive infusion medium out of the distal end of the piston channel. The clearance between the piston and the channel is sufficiently small to prevent undissolved gas in the inlet chamber from passing through the clearance. The inlet chamber may be sufficiently large to allow undissolved gas to accumulate without adversely affecting the performance of the infusion device.
摘要翻译： 植入式输注装置包括用于容纳输注介质的储存器和具有入口室，活塞和活塞通道的驱动机构。 入口室与储存器流体连通。 活塞通道与入口室流体连通，并且具有远端和近端，近端比远端更靠近入口通道。 活塞在活塞通道内可轴向运动，以将输注介质驱出活塞通道的远端。 活塞和通道之间的间隙足够小，以防止入口室中的未溶解气体通过间隙。 入口室可以足够大以允许未溶解的气体积聚而不会不利地影响输注装置的性能。
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公开(公告)号：US20080286132A1
公开(公告)日：2008-11-20
申请号：US11749460
申请日：2007-05-16
CPC分类号： A61M5/14216 , A61M5/14276 , A61M2205/103 , A61M2205/106 , F04B17/048
摘要： The present invention relates to a method and related apparatus for rotating a piston of a drug pump during the pumping stroke to reduce drug pump wear. The actuator may move a piston that pumps fluid through a pumping channel. In the present invention, the armature includes one or more openings or shapes that cause the actuator, including the armature and the piston, to rotate about a longitudinal axis of the piston during the pumping stroke. Rotation of the actuator member may help to reduce wear to the actuator member and the pump itself caused by repetitive pumping motions.
摘要翻译： 本发明涉及一种用于在泵送冲程期间旋转药泵的活塞以减少药泵磨损的方法和相关装置。 致动器可以移动通过泵送通道泵送流体的活塞。 在本发明中，电枢包括一个或多个开口或形状，其使包括电枢和活塞在内的致动器在泵送冲程期间围绕活塞的纵向轴线旋转。 致动器构件的旋转可以有助于减少由重复泵送运动引起的致动器构件和泵本身的磨损。
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公开(公告)号：US10010667B2
公开(公告)日：2018-07-03
申请号：US13275690
申请日：2011-10-18
CPC分类号： A61M5/14212 , A61M5/14276 , A61M5/1483 , A61M2005/14264 , A61M2005/14513 , A61M2205/3341 , A61M2205/8218
摘要： Techniques are disclosed for reducing the accumulation of gases in an implantable infusion device. In one example, an implantable infusion device (IID) includes a housing, an expandable and contractible reservoir, and a standoff member. The expandable and contractible reservoir is configured to store a therapeutic agent and is arranged within the housing. A first end of the reservoir is configured to collapse toward a second end of the reservoir as the reservoir contracts. The standoff member is interposed between the first end and the second end of the reservoir and is configured to hold at least a portion of the first end offset from the second end when the reservoir is in a contracted state.
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公开(公告)号：US08545484B2
公开(公告)日：2013-10-01
申请号：US13275736
申请日：2011-10-18
申请人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
发明人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
IPC分类号： A61K9/22
CPC分类号： A61M5/14276 , A61M5/16809 , A61M2205/3331 , A61M2205/3362 , A61M2205/8212 , A61M2206/22
摘要： An accumulator is employed in an implantable infusion device to provide compliance in the flow path of the device. The accumulator may act to increase the pumping accuracy and repeatability while simultaneously reducing the energy requirements of the device. In one example, the accumulator is arranged at the outlet of a fluid delivery pump of the infusion device. The accumulator includes a cover and a diaphragm biased away from the cover and configured to deflect toward the cover under pressure generated by the therapeutic agent in a flow path of the infusion device. The cover of the accumulator is configured to withstand the pressure generated by the therapeutic agent in the flow path without deforming.
摘要翻译： 在可植入输注装置中采用蓄能器以在装置的流动路径中提供顺应性。 蓄能器可以用于增加泵送精度和重复性，同时降低装置的能量需求。 在一个示例中，蓄能器布置在输液装置的流体输送泵的出口处。 蓄能器包括盖子和偏离盖子的隔膜，并被构造成在灌注装置的流动路径中由治疗剂产生的压力下向盖子偏转。 蓄能器的盖构造成能够承受流路中治疗剂产生的压力而不变形。
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公开(公告)号：US20130096503A1
公开(公告)日：2013-04-18
申请号：US13275736
申请日：2011-10-18
申请人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
发明人： James M. Haase , Ronald L. Mezera , John M. Gray , Nicholas R. Whitehead , Jeffrey P. Bodner , Brian C. Egan
CPC分类号： A61M5/14276 , A61M5/16809 , A61M2205/3331 , A61M2205/3362 , A61M2205/8212 , A61M2206/22
摘要： An accumulator is employed in an implantable infusion device to provide compliance in the flow path of the device. The accumulator may act to increase the pumping accuracy and repeatability while simultaneously reducing the energy requirements of the device. In one example, the accumulator is arranged at the outlet of a fluid delivery pump of the infusion device. The accumulator includes a cover and a diaphragm biased away from the cover and configured to deflect toward the cover under pressure generated by the therapeutic agent in a flow path of the infusion device. The cover of the accumulator is configured to withstand the pressure generated by the therapeutic agent in the flow path without deforming.
摘要翻译： 在可植入输注装置中采用蓄能器以在装置的流动路径中提供顺应性。 蓄能器可以用于增加泵送精度和重复性，同时降低装置的能量需求。 在一个示例中，蓄能器布置在输液装置的流体输送泵的出口处。 蓄能器包括盖子和偏离盖子的隔膜，并被构造成在灌注装置的流动路径中由治疗剂产生的压力下向盖子偏转。 蓄能器的盖构造成能够承受流路中治疗剂产生的压力而不变形。
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公开(公告)号：US20130096537A1
公开(公告)日：2013-04-18
申请号：US13275690
申请日：2011-10-18
IPC分类号： A61M5/142
CPC分类号： A61M5/14212 , A61M5/14276 , A61M5/1483 , A61M2005/14264 , A61M2005/14513 , A61M2205/3341 , A61M2205/8218
摘要： Techniques are disclosed for reducing the accumulation of gases in an implantable infusion device. In one example, an implantable infusion device (IID) includes a housing, an expandable and contractible reservoir, and a standoff member. The expandable and contractible reservoir is configured to store a therapeutic agent and is arranged within the housing. A first end of the reservoir is configured to collapse toward a second end of the reservoir as the reservoir contracts. The standoff member is interposed between the first end and the second end of the reservoir and is configured to hold at least a portion of the first end offset from the second end when the reservoir is in a contracted state.
摘要翻译： 公开了用于减少可植入输注装置中气体积聚的技术。 在一个示例中，植入式输注装置（IID）包括壳体，可膨胀和收缩的储存器以及支座构件。 可膨胀和收缩的储存器构造成存储治疗剂并且布置在壳体内。 储存器的第一端构造成随着储存器收缩而朝向储存器的第二端折叠。 隔离构件插入在储存器的第一端和第二端之间，并且构造成当储存器处于收缩状态时保持与第二端偏移的第一端的至少一部分。
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公开(公告)号：US09968733B2
公开(公告)日：2018-05-15
申请号：US12684436
申请日：2010-01-08
IPC分类号： A61M5/142 , F04B17/04 , F04B19/00 , F04B35/04 , F04B53/00 , F04B53/10 , A61M5/165 , A61M5/36
CPC分类号： A61M5/14276 , A61M5/14216 , A61M5/165 , A61M5/36 , A61M2205/7518 , F04B17/042 , F04B19/006 , F04B35/045 , F04B53/008 , F04B53/1032
摘要： An implantable infusion device includes a reservoir for housing an infusion medium and a drive mechanism having an inlet chamber, a piston and a piston channel. The inlet chamber is in fluid communication with the reservoir. The piston channel is in fluid communication with the inlet chamber, and has a distal end and a proximal end, the proximal end being closer to the inlet channel than the distal end. The piston is axially moveable within the piston channel to drive infusion medium out of the distal end of the piston channel. The clearance between the piston and the channel is sufficiently small to prevent undissolved gas in the inlet chamber from passing through the clearance. The inlet chamber may be sufficiently large to allow undissolved gas to accumulate without adversely affecting the performance of the infusion device.
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公开(公告)号：US08007247B2
公开(公告)日：2011-08-30
申请号：US11805124
申请日：2007-05-22
CPC分类号： F04B17/048 , A61M5/14216 , A61M5/14276 , A61M2205/8212 , F04B49/06 , F04B2201/0201 , F04B2203/0401 , F04B2203/0402 , F04B2203/0403
摘要： Detection of end of stroke for an electromagnetic pump is performed using, for example, a calculated first flux derivative.
摘要翻译： 使用例如计算出的第一通量导数来进行电磁泵的行程结束的检测。
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公开(公告)号：US4447197A
公开(公告)日：1984-05-08
申请号：US517092
申请日：1983-07-25
申请人： Donald R. Bartley , James M. Haase
发明人： Donald R. Bartley , James M. Haase
CPC分类号： B29C33/10 , B29D2030/0617 , Y10S425/812
摘要： A tire mold having air venting passages or holes is provided with plastic inserts or plugs for the vent holes along the cavity side of the mold. The inserts are composed of a plastic material having a heat distortion temperature of no less than 275.degree. F. at 66 psi in accordance with ASTM D648 and a coefficient of thermal expansion less than 8.times.10.sup.-5 in/in/.degree.C.
摘要翻译： 具有排气通道或孔的轮胎模具设置有用于沿着模具的空腔侧的通气孔的塑料插入件或塞子。 插入件根据ASTM D648在66psi下具有不低于275°F的热变形温度的塑料材料和小于8×10-5in / in /℃的热膨胀系数。
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