公开(公告)号：US07954521B2

公开(公告)日：2011-06-07

申请号：US11339966

申请日：2006-01-25

申请人： Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

发明人： Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

IPC分类号： B65B1/04 ,  B65D39/00

CPC分类号： B65B55/10 ,  B65B3/003 ,  B65B7/2842 ,  B65B51/22 ,  B65B55/025 ,  B65D51/002 ,  B65D51/18 ,  B65D2251/0015 ,  B65D2251/0078

摘要： A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

摘要翻译： 提供容器和方法来储存含有液体产品的脂肪。 容器包括限定用于接收产品的储存室的主体和容器封闭件。 第一材料部分形成至少大部分覆盖储存室的表面区域，该表面区域可接触其中的任何产品。 身体和第一材料部分都不会将超过预定量的可浸出物浸入产品中或者不期望地改变其味道特征。 针可穿透和可热再密封的第二材料部分（i）覆盖在第一材料部分上并且不能接触储存室内的任何产品，或（ii）形成覆盖存储室的基本上较小的表面区域，其可以与其中的任何产品接触 到第一材料部分。 密封部分可与主体接合以在容器封闭件和主体之间形成基本上干燥的气密密封。

公开(公告)号：US20110052768A1

公开(公告)日：2011-03-03

申请号：US12894224

申请日：2010-09-30

申请人： Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

发明人： Daniel Py ,  Norbert Assion ,  Nathaniel Houle ,  Debashis Sahoo ,  M. Jeffrey Willey ,  Eric E. Hartman ,  John Guthy

IPC分类号： B65B55/08 ,  B65D53/00 ,  B67C3/02

CPC分类号： B65B55/10 ,  B65B3/003 ,  B65B7/2842 ,  B65B51/22 ,  B65B55/025 ,  B65D51/002 ,  B65D51/18 ,  B65D2251/0015 ,  B65D2251/0078

摘要： A container and method are provided for storing fat containing liquid products. The container includes a body defining a storage chamber for receiving the product, and a container closure. A first material portion forms at least most of the surface area overlying the storage chamber that can contact any product therein. Neither the body nor the first material portion leach more than a predetermined amount of leachables into the product or undesirably alter a taste profile thereof. A needle penetrable and thermally resealable second material portion either (i) overlies the first material portion and cannot contact any product within the storage chamber, or (ii) forms a substantially lesser surface area overlying the storage chamber that can contact any product therein in comparison to the first material portion. A sealing portion is engageable with the body to form a substantially dry hermetic seal between the container closure and body.

摘要翻译： 提供容器和方法来储存含有液体产品的脂肪。 容器包括限定用于接收产品的储存室的主体和容器封闭件。 第一材料部分形成至少大部分覆盖储存室的表面区域，该表面区域可接触其中的任何产品。 身体和第一材料部分都不会将超过预定量的可浸出物浸入产品中或者不期望地改变其味道特征。 针可穿透和可热再密封的第二材料部分（i）覆盖在第一材料部分上并且不能接触储存室内的任何产品，或（ii）形成覆盖存储室的基本上较小的表面区域，其可以与其中的任何产品接触 到第一材料部分。 密封部分可与主体接合以在容器封闭件和主体之间形成基本上干燥的气密密封。

公开(公告)号：US20100316774A1

公开(公告)日：2010-12-16

申请号：US12861354

申请日：2010-08-23

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

IPC分类号： A61J9/00 ,  B65B55/08

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US07780023B2

公开(公告)日：2010-08-24

申请号：US11786206

申请日：2007-04-10

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

IPC分类号： A61J9/00 ,  A61J11/04

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US20050155987A1

公开(公告)日：2005-07-21

申请号：US10976349

申请日：2004-10-28

申请人： Daniel Py ,  Norbert Assion ,  Julian Chan

发明人： Daniel Py ,  Norbert Assion ,  Julian Chan

IPC分类号： A45D40/26 ,  B65D25/40 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D35/44 ,  B65D35/50 ,  B65D37/00 ,  B65D47/20

CPC分类号： B65D47/205 ,  A45D40/26 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D83/0055

摘要： A container including a nozzle and body depending therefrom. The body is preferably tubular and defines an interior which retains a product to be dispensed. A cap engages the nozzle to prevent inadvertent release of the product. In order to dispense the product, the cap is removed and pressure is applied to the body and the nozzle allows release of the product. The nozzle releases the product without exposing the remaining product to the external atmosphere, thus the sterility of the interior of the body is maintained and the shelf life of the product is increased. The nozzle includes an inner body, coupled to the tubular body, surrounded by a flexible outer cover. A seam between the inner body and flexible outer cover forms a one-way release valve wherein a portion of the seam remains closed during dispensing the product.

摘要翻译： 一种容器，其包括从其排出的喷嘴和主体。 主体优选地是管状的并且限定保持要分配的产品的内部。 盖子与喷嘴接合以防止产品的意外释放。 为了分配产品，盖被去除并且压力施加到主体上，并且喷嘴允许释放产品。 喷嘴释放产品而不将剩余的产品暴露于外部大气，从而维持身体内部的不整洁性并且提高了产品的保质期。 该喷嘴包括一个连接到管状主体的内部主体，被一个柔性的外盖包围。 内体和柔性外盖之间的接缝形成单向释放阀，其中在分配产品期间，接缝的一部分保持关闭。

公开(公告)号：US20070283666A1

公开(公告)日：2007-12-13

申请号：US11786206

申请日：2007-04-10

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willley

IPC分类号： B65B55/02

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US08376003B2

公开(公告)日：2013-02-19

申请号：US12861354

申请日：2010-08-23

申请人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

发明人： Daniel Py ,  Benoit Adamo ,  John Guthy ,  Nathaniel Houle ,  Brian Tulley ,  Jeffrey Willey

IPC分类号： B65B3/04 ,  A61J9/00

CPC分类号： A61J11/0005 ,  A61J1/1406 ,  A61J9/003 ,  A61J11/04 ,  B65D51/002

摘要： A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber.

摘要翻译： 提供容器用于储存诸如含脂肪的液体产品的产品，并且包括限定用于容纳产品的室的主体; 以及容器封闭件，其包括用于密封腔室内的产品的密封部分。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件; 与腔室流体连通的乳头，其在产品在腔室中储存期间相对于环境大气密封腔室，并且可以打开以从腔室通过其分配产品; 以及针可穿透和可激光重新密封的部分，其可由针穿透，用于用产品无菌填充腔室，并且通过施加激光辐射可热再密封以密封腔室内的产品。

公开(公告)号：US20050029307A1

公开(公告)日：2005-02-10

申请号：US10691270

申请日：2003-10-21

申请人： Daniel Py ,  Norbert Assion ,  Julian Chan ,  Joseph Ting

发明人： Daniel Py ,  Norbert Assion ,  Julian Chan ,  Joseph Ting

IPC分类号： B67D7/60 ,  A61F9/00 ,  B05B11/00 ,  B65D81/24 ,  B67D7/84 ,  B67D5/42

CPC分类号： A61F9/0008 ,  B05B11/00412 ,  B05B11/0054 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3092 ,  B05B11/3094 ,  B65B3/003 ,  B65D81/245 ,  Y10T29/49826

摘要： An ophthalmic dispenser has a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. A spring is drivingly connected to the housing and moves at least one of the pump and housing relative to the other to actuate the pump. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.

摘要翻译： 眼科分配器具有限定流体接收室的刚性壳体，可接收在流体接收室内的柔性气囊，与流体接收室流体连通的泵，以及具有限定环形轴向 - 延伸阀座，联接在阀座和泵之间流体连通的出口孔，以及围绕阀座延伸并在其间形成环形的轴向延伸的接口的柔性阀盖。 阀接口可连接到出口孔流体连通，并且阀盖的至少一部分可在（i）常闭位置与阀盖之间移动，阀盖与阀座接合以闭合界面并形成流体密封 ，并且（ii）打开位置，其中阀盖的至少一部分响应于在大于阀打开压力的压力下流过出口孔的泵送流体而与阀座间隔开，以允许加压流体在其间通过 。 弹簧驱动地连接到壳体并且相对于另一个移动泵和壳体中的至少一个以致动泵。 刚性壳体可安装在盒中，其又可安装在分配器壳体内，该分配器壳体包括用于同时致动眼睑下压器和泵的眼睑下压器和触发器。

公开(公告)号：US20050263543A1

公开(公告)日：2005-12-01

申请号：US11195520

申请日：2005-08-01

申请人： Daniel Py ,  Norbert Assion ,  Julian Chan

发明人： Daniel Py ,  Norbert Assion ,  Julian Chan

IPC分类号： A61M5/142 ,  A45D40/26 ,  A61M5/315 ,  A61M5/50 ,  A61M11/00 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D35/44 ,  B65D47/20 ,  G01F11/02 ,  B67D5/42 ,  G01F11/00

CPC分类号： B65D47/2031 ,  A45D40/26 ,  A61M5/31586 ,  A61M5/31595 ,  A61M5/50 ,  A61M5/502 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D35/44 ,  G01F11/027

摘要： A syringe is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials which may react upon exposure to air, such as glue. The syringes include a body and a plunger. Means are provided in the syringe body and the plunger to effect controlled movement of the plunger into the syringe to permit delivery of a pre-determined amount of the substance contained in the syringe. A one-way valve is provided at the dispensing tip of the syringe to hermetically seal the portion of the syringe containing the substance to be dispensed.

摘要翻译： 提供注射器用于向人或动物（例如药物，药物，化妆品和食品）递送受控量的计量量的任何不同物质，或者输送在暴露于空气中可能反应的材料，例如胶 。 注射器包括身体和柱塞。 装置设置在注射器主体和柱塞中以实现柱塞到注射器中的受控运动，以允许输送预定量的包含在注射器中的物质。 在注射器的分配尖端处设置单向阀以气密地密封包含待分配物质的注射器的部分。

公开(公告)号：US20080083788A1

公开(公告)日：2008-04-10

申请号：US11900227

申请日：2007-09-10

申请人： Daniel Py ,  Brian Tulley ,  Jeff Willey

发明人： Daniel Py ,  Brian Tulley ,  Jeff Willey

IPC分类号： B67D5/00 ,  B65D35/56 ,  B65D37/00 ,  B67D5/06

CPC分类号： B67D1/10 ,  B05B11/0054 ,  B05B11/303 ,  B05B11/3032 ,  B65D75/5866 ,  B65D75/5883 ,  B65D77/067 ,  B67D1/0082 ,  B67D1/02 ,  B67D2001/0827

摘要： An apparatus comprises a hermetically sealed, sterile storage chamber, a dispensing valve including a hermetically sealed, sterile inlet; a pump coupled between the dispensing valve and storage chamber; and a sealing surface located between the dispensing valve and storage chamber. The sealing surface and/or the dispensing valve is movable relative to the other between (i) a sealing position hermetically sealing the dispensing valve relative to the storage chamber to thereby prevent fluid flow therebetween, and (ii) a non-sealing position allowing fluid flow therebetween.

摘要翻译： 一种装置包括密封的无菌储存室，分配阀，包括气密密封的无菌入口; 耦合在分配阀和存储室之间的泵; 以及位于分配阀和储存室之间的密封表面。 密封表面和/或分配阀可以在（i）密封位置之间相对于另一个移动，密封位置相对于储存室气密地密封分配阀，从而防止流体在其间流动，以及（ii）非密封位置，允许流体 流动。