公开(公告)号：US10479983B2

公开(公告)日：2019-11-19

申请号：US14909041

申请日：2014-07-24

Applicant: DANISCO US INC

Inventor： Nicholai Douglas ,  Maria Foukaraki ,  Ronaldus Wilhelmus Hommes ,  Thijs Kaper ,  Bradley R. Kelemen ,  Slavko Kralj ,  Suzanne E. Lantz ,  Jonathan K. Lassila ,  Igor Nikolaev ,  Daniel Esteban Torres-Pazmino ,  Wilhelmus Van Der Kley ,  Johannes Franciscus Thomas Van Lieshout ,  Sander Van Stigt Thans

IPC: C12N9/14 ,  C12N15/09 ,  C12N9/42 ,  C12N9/02 ,  C12P19/02 ,  C12P19/14 ,  C12N9/24 ,  A61K38/00

Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

公开(公告)号：US10167460B2

公开(公告)日：2019-01-01

申请号：US14909031

申请日：2014-07-24

Applicant: DANISCO US INC

Inventor： Maria Foukaraki ,  Ronaldus Wilhelmus Hommes ,  Thijs Kaper ,  Bradley R. Kelemen ,  Slavko Kralj ,  Suzanne E. Lantz ,  Igor Nikolaev ,  Wilhelmus Van Der Kley ,  Johan Franciscus Thomas Van Lieshout ,  Sander Van Stigt Thans

IPC: C12N9/02 ,  C12N9/42 ,  C12P19/14 ,  C12P19/02

Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.

公开(公告)号：US20180002683A1

公开(公告)日：2018-01-04

申请号：US15536817

申请日：2015-12-18

Applicant: DANISCO US INC.

Inventor： Zachary Q. Beck ,  Meredith K. Fujdala ,  Henrik Hansson ,  Thijs Kaper ,  Slavko Kralj ,  Amy D. Liu ,  Nils Egil Mikkelsen ,  Mats Sandgren

IPC: C12N9/24 ,  C12P19/02 ,  C12P19/14 ,  C12N9/42

CPC classification number: C12N9/248 ,  C12N9/2445 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01021 ,  C12Y302/01037

Abstract: Provided are certain glycosyl hydrolase family 3 (GH3) beta-xylosidases engineered to acquire beta-glucosidase activities. Provided also are compositions comprising such multi-functional GH3 enzymes and methods of use or industrial applications thereof.