公开(公告)号：US20190169585A1

公开(公告)日：2019-06-06

申请号：US16275582

申请日：2019-02-14

Applicant: DANISCO US INC.

Inventor： Benjamin Bower ,  Mark Emptage ,  William D. Hitz ,  Megan Yee Hsi ,  Thijs Kaper ,  Bradley R. Kelemen ,  Steven Kim ,  Suzanne E. Lantz ,  Edmund A. Larenas ,  Colin Mitchinson ,  Keith Dumont Wing

IPC: C12N9/24 ,  C12N9/20 ,  C12P19/00 ,  C12P19/14 ,  C12N9/42 ,  C12P19/02 ,  C12N9/16 ,  C12N9/08 ,  C12N9/04

Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.

公开(公告)号：US09523087B2

公开(公告)日：2016-12-20

申请号：US14189943

申请日：2014-02-25

Applicant: Danisco US Inc.

Inventor： Wolfgang Aehle ,  Richard R. Bott ,  Benjamin S. Bower ,  Jonathan Caspi ,  David A. Estell ,  Frits Goedegebuur ,  Ronaldus Wilhelmus Joannes Hommes ,  Thijs Kaper ,  Bradley R. Kelemen ,  Slavko Kralj ,  Johannes Franciscus Thomas Van Lieshout ,  Igor Nikolaev ,  Sander Van Stigt Thans ,  Louise Wallace ,  Gudrun Vogtentanz ,  Mats Sandgren

IPC: C12N9/42 ,  C12N9/52 ,  C07H21/04

CPC classification number: C12N9/2437 ,  C12Y302/01091 ,  Y02E50/17

Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.

Abstract translation: 本公开涉及纤维素酶变体。 特别地，本公开涉及具有改善的表达，活性和/或稳定性的纤维素酶变体。 还描述了编码纤维素酶变体的核酸，包含纤维素酶变体的组合物及其使用方法。

公开(公告)号：US09938551B2

公开(公告)日：2018-04-10

申请号：US14650285

申请日：2013-12-10

Applicant: Danisco US Inc.

Inventor： Richard R. Bott ,  Maria Foukaraki ,  Ronaldus Wilhelmus Hommes ,  Thijs Kaper ,  Bradley R. Kelemen ,  Slavko Kralj ,  Igor Nikolaev ,  Mats Sandgren ,  Johannes Franciscus Thomas Van Lieshout ,  Sander Van Stigt Thans

IPC: C12P19/14 ,  C12P19/02 ,  C12N9/42

CPC classification number: C12P19/14 ,  C12N9/2434 ,  C12N9/2437 ,  C12P19/02 ,  C12Y302/01091

Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.

公开(公告)号：US09695407B2

公开(公告)日：2017-07-04

申请号：US14662932

申请日：2015-03-19

Applicant: Danisco US Inc.

Inventor： Luis Cascao-Pereira ,  Thijs Kaper ,  Bradley R. Kelemen ,  Amy D. Liu

IPC: C12N9/14 ,  C12N9/42 ,  C12P19/14 ,  C12P19/02

CPC classification number: C12N9/2437 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004 ,  C12Y302/01091 ,  Y02E50/16 ,  Y02E50/17

Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.

公开(公告)号：US20250051748A1

公开(公告)日：2025-02-13

申请号：US18720046

申请日：2022-12-15

Applicant: Danisco US Inc.

Inventor： Viktor Yuryevich Alekseyev ,  Lilia Babe ,  Lydia Dankmeyer ,  Frits Goedegebuur ,  Roopa Ghirnikar ,  Thijs Kaper ,  Harm Mulder ,  Nils Henning Redestig ,  Sander Van Stigt Thans

IPC: C12N9/54 ,  C11D3/386 ,  C12N9/26

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20240279632A1

公开(公告)日：2024-08-22

申请号：US18640088

申请日：2024-04-19

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Viktor Yuryevich Alekseyev ,  Joshua Roy Basler ,  H. Billur Engin ,  David A. Estell ,  Roopa Santosh Ghirnikar ,  Frits Goedegebuur ,  Thijs Kaper ,  Mulder Harm ,  Sina Pricelius ,  Sander Van Stigt Thans ,  Gudrun Vogtentanz

IPC: C12N9/54 ,  C11D3/386 ,  C12N9/52

CPC classification number: C12N9/54 ,  C11D3/386 ,  C11D3/38627 ,  C11D3/38645 ,  C11D3/38654 ,  C12N9/52 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.

公开(公告)号：US20230257728A1

公开(公告)日：2023-08-17

申请号：US18166707

申请日：2023-02-09

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Lydia Dankmeyer ,  David A. Estell ,  Frits Goedegebuur ,  Thijs Kaper ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/386 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.

公开(公告)号：US20170349922A1

公开(公告)日：2017-12-07

申请号：US15522312

申请日：2015-10-27

Applicant: Danisco US Inc.

Inventor： Bemjamin S. Bower ,  Jimmy Chan ,  Meredith K. Fujdala ,  Thijs Kaper ,  Suzanne E. Lantz ,  Kirstin Y. Nose Crotty ,  Amr R. Toppozada

IPC: C12P19/14 ,  C12P19/02 ,  C12N9/42

CPC classification number: C12P19/14 ,  C12N9/2445 ,  C12P19/02 ,  C12Y302/01021

Abstract: The present compositions and methods relate to a beta-glucosidase from Glomerella graminicola, polynucleotides encoding the beta-glucosidase, and methods of making and/or use thereof. Formulations containing the beta-glucosidase may be suitable for use in hydrolyzing lignocellulosic biomass substrates.

公开(公告)号：US20240174953A1

公开(公告)日：2024-05-30

申请号：US18285392

申请日：2022-04-21

Applicant: Danisco US Inc.

Inventor： Lilia M Babe ,  Xiaogang Gu ,  Thijs Kaper

IPC: C11D3/386 ,  C11D1/72 ,  C12N9/50

CPC classification number: C11D3/38618 ,  C11D1/72 ,  C12N9/50 ,  C12Y304/21 ,  C11D2111/12 ,  C11D2111/14

Abstract: Described herein is at least one novel trypsin-like serine protease polypeptide and uses thereof. Further described herein are cleaning compositions containing at least one polypeptide described herein, wherein said composition can be used to clean fabrics and hard surfaces. Even further described herein is at least one cleaning composition selected from a laundry detergent, a dishwashing detergent (e.g., automatic and hand dish), and a personal care composition. Even still further, at least one polypeptide having improved soil removal and/or stability compared to at least one reference polypeptide is described herein.

公开(公告)号：US11946081B2

公开(公告)日：2024-04-02

申请号：US16471686

申请日：2017-12-19

Applicant: DANISCO US INC.

Inventor： Lilia Maria Babe ,  Lydia Dankmeyer ,  Frits Goedegebuur ,  Thijs Kaper ,  Harm Mulder ,  Sina Pricelius

IPC: C12N9/54 ,  C11D3/386

CPC classification number: C12N9/54 ,  C11D3/38681 ,  C12Y304/21062

Abstract: Disclosed herein is one or more subtilisin variant. nucleic acid encoding same. and compositions and methods related to the production and use thereof. including one or more Bacillus gibsonii-clade subtilisin variant that has improved soil removal compared to one or more reference subtilisin.