公开(公告)号：US20220346993A1

公开(公告)日：2022-11-03

申请号：US17862271

申请日：2022-07-11

Applicant: Edwards Lifesciences Corporation

Inventor： HARISH MANICKAM SRINIMUKESH ,  Matthew Michael Becerra ,  Mark Chau ,  Jesse Robert Edwards ,  Garrett Dallas Johnson ,  David Robert Landon ,  Ju Nie Leong ,  Hieu Minh Luong ,  Hiroshi Okabe ,  Matthew A. Peterson ,  Kevin M. Stewart ,  Julio Cesar Sanchez

IPC: A61F2/95

Abstract: Apparatuses and methods for loading and deploying implants from delivery apparatuses. The apparatuses in certain embodiments may comprise crimping devices for compressing an implant for insertion into a portion of a delivery apparatus. The apparatuses in certain embodiments may comprise features of delivery apparatuses allowing for improved loading and deployment of an implant from the delivery apparatuses.

公开(公告)号：US20220287833A1

公开(公告)日：2022-09-15

申请号：US17825071

申请日：2022-05-26

Applicant: Edwards Lifesciences Corporation

Inventor： David Robert Landon ,  Glen T. Rabito ,  Hieu Minh Luong

IPC: A61F2/24 ,  B21D39/04 ,  A61F2/95

Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.

公开(公告)号：US20210022863A1

公开(公告)日：2021-01-28

申请号：US17071745

申请日：2020-10-15

Applicant: Edwards Lifesciences Corporation

Inventor： Alexander H. Cooper ,  David Robert Landon ,  Kevin M. Stewart ,  Garrett Dallas Johnson ,  Glen T. Rabito ,  Tarannum Ishaq Gutierrez ,  Hiroshi Okabe ,  Ramon Aguilar, JR. ,  Jesse Robert Edwards ,  Taylor Jacob Scheinblum ,  Patrick Chow ,  Julio Cesar Sanchez ,  Hieu Minh Luong

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/01

Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement mitral valve to a native mitral valve location. The steerable delivery system can contain a steerable rail configured for multi-plane bending to direct a distal end of the delivery system.

公开(公告)号：US20200297481A1

公开(公告)日：2020-09-24

申请号：US16843122

申请日：2020-04-08

Applicant: Edwards Lifesciences Corporation

Inventor： Travis Zenyo Oba ,  Matthew A. Peterson ,  Glen T. Rabito ,  Alexander H. Cooper ,  David Robert Landon ,  J. Brent Ratz ,  Seung-Beom Yi

IPC: A61F2/24 ,  A61L27/04 ,  A61L27/36

Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

公开(公告)号：US20250107892A1

公开(公告)日：2025-04-03

申请号：US18981479

申请日：2024-12-14

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： David L. Hauser ,  David Robert Landon ,  Rani Abdullah Mahmoudi ,  Eric Robert Dixon

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to be expanded within a native valve annulus, engage surrounding tissue, and constricted tissue inward to enhance contact between the tissue and the valve. The heart valve may have a structural valve stent with an outer constricting structure having tissue-engaging members or anchors. The constricting structure may be intrinsic or extrinsic. One intrinsic version includes a plurality of arms that are arranged to constrict inward toward a central valve portion, or a fabric structure with tissue anchors and surrounding an inner valve member may be cinched to pull the tissue inward. The anchors may engage tissue around the annulus in the atrium, or surround leaflets in the ventricle, or grasp leaflets from within.

公开(公告)号：US20240307175A1

公开(公告)日：2024-09-19

申请号：US18673188

申请日：2024-05-23

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander H. Cooper ,  Juliet Laura Schwartz ,  Hannah Marie Glas ,  Matthew Michael Becerra ,  David Robert Landon ,  Siddharth Vad ,  Taylor Jacob Scheinblum ,  Matthew A. Peterson ,  Wei Gan

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0069 ,  A61F2250/006 ,  A61F2250/0068

Abstract: Apparatuses, systems, and methods for prosthetic valves. Examples of prosthetic valves may be configured to anchor to an interior surface of a heart valve. Such prosthetic valves, in examples, may include a single frame that supports a plurality of prosthetic valve leaflets. In examples, multiple frames may be utilized to anchor to a heart valve and one or more of the frames may support a plurality of prosthetic valve leaflets.

公开(公告)号：US20240197301A1

公开(公告)日：2024-06-20

申请号：US18591604

申请日：2024-02-29

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Taylor Jacob Scheinblum ,  David Robert Landon ,  Kevin M. Stewart ,  Matthew Michael Becerra ,  Alexander H. Cooper ,  Wei Gan

IPC: A61B17/00 ,  A61B17/11

CPC classification number: A61B17/00234 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1139

Abstract: Traditional CABG procedures are performed by accessing the chest cavity and stopping the heart. However, off-pump CABG is becoming more wide-spread in use. Transcatheter CABG procedures are particularly advantageous and thus may become prevalent. A transcatheter CABG procedure can advantageously reduce complications, procedure time, and recovery time as well as providing benefits of being an off-pump, beating heart procedure. Accordingly, disclosed herein are several mechanisms and methods for accessing, implant anchoring, and visualization during a transcatheter CABG procedure.

公开(公告)号：US20230404753A1

公开(公告)日：2023-12-21

申请号：US18230881

申请日：2023-08-07

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Hieu Minh Luong ,  Julio Cesar Sanchez ,  Alexander H. Cooper ,  Jesse Robert Edwards ,  Hiroshi Okabe ,  Karen Fromell Nesbitt ,  David Robert Landon ,  Nikolai Brent Poulsen ,  Taylor Jacob Scheinblum ,  Eric Robert Dixon ,  Cooper Ryan Rickerson ,  Zachary Charles VanEvery

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2439

Abstract: A delivery system includes a suture attachment mechanism for maintaining a connection to a heart valve after initial deployment, thereby allowing recapture of the heart valve if desired. A plurality of suture portions is provided along a distal end portion of the delivery system, each suture portion having a first end fixed to the delivery system and a second end releasably coupled to a retention member on the delivery system. A knob on a handle of the delivery system is actuated for causing the second end of each suture portion to be released from its respective retention member, thereby allowing the suture portions to be decoupled from the heart valve. The suture portions are located only along a distal end portion of the delivery system for improving reliability and consistency.

公开(公告)号：US11344409B2

公开(公告)日：2022-05-31

申请号：US16851959

申请日：2020-04-17

Applicant: Edwards Lifesciences Corporation

Inventor： David Robert Landon ,  Glen T. Rabito ,  Hieu Minh Luong

IPC: A61F2/24 ,  B21D39/04 ,  A61F2/95

Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.

公开(公告)号：US20210401575A1

公开(公告)日：2021-12-30

申请号：US17469817

申请日：2021-09-08

Applicant: Edwards Lifesciences Corporation

Inventor： David Robert Landon ,  Alexander H. Cooper ,  Julio Cesar Sanchez ,  Glen T. Rabito ,  J. Brent Ratz ,  Tarannum Ishaq Gutierrez ,  Ramon Aguilar, JR.

IPC: A61F2/24 ,  A61M25/00 ,  A61M25/01

Abstract: Devices, systems and methods are described herein to provide improved steerability for delivering a prosthesis to a body location, for example, for delivering a replacement valve to a native valve location in a heart. Disclosed are a number of features that can improve steerability or release of the prosthesis into the body location. In one preferred delivery system, a proximal handle can be manipulated to apply tension to a pair of diametrically opposed axial runner wires extending through lumens in a wall of a flexible tubular shaft. By applying tension to a pair of axial runner wires, the tubular shaft can be stiffened along a plane extending substantially through the pair of axial runner wires, while the shaft is permitted to freely bend in a perpendicular plane. This feature advantageously provides the ability to adjust the steerability and flexibility of a tubular shaft to meet the requirements of a particular procedure.