公开(公告)号：US20240299166A1

公开(公告)日：2024-09-12

申请号：US18664760

申请日：2024-05-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alexander H. Cooper ,  Juliet Laura Schwartz ,  Hannah Marie Glas ,  Matthew Michael Becerra ,  David Robert Landon ,  Siddharth Vad ,  Taylor Jacob Scheinblum ,  Matthew A. Peterson ,  Wei Gan

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2220/0016 ,  A61F2230/0041 ,  A61F2230/0093 ,  A61F2250/001

Abstract: A prosthetic valve includes an expandable valve frame and leaflets supported therein. A plurality of elongate anchor arms extends from an outlet end portion of the valve frame. Each elongate anchor arm includes anchoring protrusions, such as barbs, for engaging surrounding tissue. During delivery to the treatment site, the anchoring protrusions face inwardly. When released from the delivery catheter, the anchoring arms evert such that the anchoring protrusions reverse orientation and face outwardly. In this position, the protrusions can engage surrounding tissue and thereby secure the prosthetic valve within a native heart valve.

公开(公告)号：US20230200980A1

公开(公告)日：2023-06-29

申请号：US18111278

申请日：2023-02-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Matthew A. Peterson ,  Siddharth Vad ,  Scott Louis Shary ,  Taylor Jacob Scheinblum ,  Kevin M. Golemo ,  Yevgeniy Davidovich Kaufman ,  David Robert Landon

IPC: A61F2/24

CPC classification number: A61F2/2409 ,  A61F2220/0008 ,  A61F2250/0039 ,  A61F2250/007

Abstract: Apparatuses, systems, and methods for prosthetic valves. Embodiments of prosthetic valves may include sealing bodies configured for an anchor to at least partially pass through. The pass through may allow for the sealing body to seal to a portion of a patient's heart in the event of a miscapture of a leaflet by the anchor. Embodiments may include modular valve systems and prosthetic valves including anchors for coupling to chordae, trabeculae, or papillary structures of a patient's heart. Embodiments may include prosthetic valves including anchors for engaging calcification of a patient's native valve.

公开(公告)号：US20220104940A1

公开(公告)日：2022-04-07

申请号：US17553566

申请日：2021-12-16

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.

公开(公告)号：US20190328515A1

公开(公告)日：2019-10-31

申请号：US16506886

申请日：2019-07-09

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.

公开(公告)号：US20240008978A1

公开(公告)日：2024-01-11

申请号：US18371303

申请日：2023-09-21

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Rupesh Gajanan Nawalakhe ,  Sandip Vasant Pawar ,  Siddharth Vad ,  Matthew A. Peterson ,  David Robert Landon ,  Zachary Charles VanEvery

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2002/0081

Abstract: A fabric having a honeycomb weave pattern is provided for use with medical implants. The fabric may be heat treated to increase a thickness and texture of the fabric. The fabric may be compliant and compressible for providing cushioning within a patient's body. For example, the fabric may be applied to a prosthetic valve to cushion a portion of the prosthetic heart valve. The fabric may also be textured to provide enhanced friction between the prosthetic heart valve and the surrounding native tissue. Enhanced friction may be achieved by weave patterns or by the inclusion of protrusions or barbs in the fabric.

公开(公告)号：US11224507B2

公开(公告)日：2022-01-18

申请号：US16506886

申请日：2019-07-09

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.

公开(公告)号：US20250152341A1

公开(公告)日：2025-05-15

申请号：US19026135

申请日：2025-01-16

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.

公开(公告)号：US20250107889A1

公开(公告)日：2025-04-03

申请号：US18981502

申请日：2024-12-14

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Kevin M. Stewart ,  Siddharth Vad ,  Jesse Robert Edwards ,  David Robert Landon ,  Jonathan Yeh ,  Hieu Minh Luong ,  Harish Manickam Srinimukesh ,  Alyssa Nicole Knauer

IPC: A61F2/24 ,  A61L27/36

Abstract: Apparatuses, systems, and methods for prosthetic valves. An implantation site may comprise a native heart valve or another implantation site in examples. Examples may be utilized for improved anchoring and sealing of flow (e.g., paravalvular leakage) with a native heart valve having calcification. Examples may reduce the possibility of obstruction of a left ventricular outflow tract (LVOT) of a heart, whether resulting from implantation of a prosthetic valve or otherwise.

公开(公告)号：US20240299163A1

公开(公告)日：2024-09-12

申请号：US18658829

申请日：2024-05-08

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Taylor Jacob Scheinblum ,  Hieu Minh Luong ,  David Robert Landon ,  Siddharth Vad ,  Ramon Aguilar, JR. ,  David M. Taylor ,  Jesse Robert Edwards ,  Brandon Sina Dehdashtian

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2436 ,  A61F2220/0008

Abstract: Devices, systems, and methods relate to implants, such as prosthetic valves for replacing native heart valves. Delivery systems for delivering the implants to an implantation site are also disclosed herein. A prosthetic valve may include a valve body supporting a plurality of prosthetic valve leaflets and one or more adjustable anchors coupled to the valve body for anchoring the prosthetic valve to leaflets of a native heart valve, wherein at least one of the adjustable anchors is axially slidable relative to the valve body for conforming to the native anatomy of the native heart valve.

公开(公告)号：US10350062B2

公开(公告)日：2019-07-16

申请号：US15653390

申请日：2017-07-18

Applicant: Edwards Lifesciences Corporation

Inventor： Matthew A. Peterson ,  Seung-Beom Yi ,  Siddharth Vad ,  Travis Zenyo Oba ,  Lauren R. Freschauf ,  Amanda French ,  Yaron Keidar ,  Yuanlong Du ,  Gregory Bak-Boychuk ,  Kevin M. Golemo ,  Alexander H. Cooper

IPC: A61F2/24

Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.