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公开(公告)号：US12121438B2
公开(公告)日：2024-10-22
申请号：US17686006
申请日：2022-03-03
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Jane M. Olin
CPC classification number: A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2412 , A61F2002/9583 , A61F2220/0016
Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
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公开(公告)号：US11877929B2
公开(公告)日：2024-01-23
申请号：US16841100
申请日：2020-04-06
Applicant: Edwards Lifesciences Corporation
Inventor： Walter Lee , Mark M. Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
CPC classification number: A61F2/2433 , A61F2/958 , A61F2/484 , A61F2/9517 , A61F2002/9586 , A61F2250/0003 , A61F2250/0021 , A61M25/1002 , A61M25/10184 , A61M2025/1013 , A61M2025/1084
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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公开(公告)号：US11458014B2
公开(公告)日：2022-10-04
申请号：US16703695
申请日：2019-12-04
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Walter Lee , Mark M. Dehdashtian , Kristopher J. Yee
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US11266500B2
公开(公告)日：2022-03-08
申请号：US16438345
申请日：2019-06-11
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Jane M. Olin
Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
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公开(公告)号：US10512536B2
公开(公告)日：2019-12-24
申请号：US15795176
申请日：2017-10-26
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Mark M. Dehdashtian , Raffaele Mazzei
IPC: A61F2/24
Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
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Patent Agency Ranking
公开(公告)号：US10314702B2
公开(公告)日：2019-06-11
申请号：US15596409
申请日：2017-05-16
Applicant: Edwards Lifesciences Corporation
Inventor： Mark M. Dehdashtian , Jane M. Olin
Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
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公开(公告)号：US20180272116A1
公开(公告)日：2018-09-27
申请号：US15991979
申请日：2018-05-29
Applicant: Edwards Lifesciences Corporation
Inventor： Thomas Walther , Mark M. Dehdashtian , Teodoro S. Jimenez , Norma A. Garcia
CPC classification number: A61M39/22 , A61M1/3659 , A61M25/0029 , A61M25/0041 , A61M25/0043 , A61M25/007 , A61M2025/0034 , A61M2025/0039 , A61M2025/0076 , A61M2025/0681 , A61M2210/08
Abstract: A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. The cannula has a secondary opening proximal of the distal opening, and may include a movable tubular extension selectively extendable from the cannula via the secondary opening. The tubular extension may be in fluid connection with the cannula first lumen and/or a cannula second lumen. The tubular extension may have distal and/or side openings, with the openings providing antegrade fluid perfusion. The cannula second lumen may be separate from the first lumen, so that perfusion can be selectively provided to just the cannula distal opening, just the secondary opening/tubular extension, or simultaneously to both the distal opening and secondary opening/tubular extension.
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公开(公告)号：US20170319341A1
公开(公告)日：2017-11-09
申请号：US15662021
申请日：2017-07-27
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Walter Lee , Mark M. Dehdashtian , Kristopher J. Yee
CPC classification number: A61F2/2427 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2220/0016 , A61F2220/005 , A61M25/0133 , A61M25/0136 , A61M25/0138 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M2025/015
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号：US20240115379A1
公开(公告)日：2024-04-11
申请号：US18542664
申请日：2023-12-16
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Walter Lee , Mark M. Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
CPC classification number: A61F2/2433 , A61F2/958 , A61M25/10184
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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公开(公告)号：US20230025110A1
公开(公告)日：2023-01-26
申请号：US17958105
申请日：2022-09-30
Applicant: Edwards Lifesciences Corporation
Inventor： Teodoro S. Jimenez , Walter Lee , Mark M. Dehdashtian , Kristopher J. Yee
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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