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公开(公告)号:US12274616B2
公开(公告)日:2025-04-15
申请号:US17958105
申请日:2022-09-30
Applicant: Edwards Lifesciences Corporation
Inventor: Teodoro S. Jimenez , Walter Lee , Mark M. Dehdashtian , Kristopher J. Yee
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
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公开(公告)号:US20230053985A1
公开(公告)日:2023-02-23
申请号:US18046078
申请日:2022-10-12
Applicant: Edwards Lifesciences Corporation
Inventor: Kristen Hicks , Michael C. Murad , Michael R. Bialas , Walter Lee
IPC: A61F2/24
Abstract: A delivery apparatus comprises a handle, a first shaft, and a second shaft. The first shaft extends through and is movable axially relative to the second shaft. The delivery apparatus comprises an inflatable balloon having a proximal end portion coupled to the second shaft and a distal end portion of the balloon coupled to the first shaft. An inflation hub assembly comprises an inflation manifold and a piston, wherein the inflation manifold comprises a main body defining a main lumen and an inflation port defining an inflation port lumen. The piston extends into the main lumen and is slidable relative to the inflation manifold. A proximal end portion of the first shaft is coupled to the piston. The piston is moveable relative to the inflation manifold in proximal and distal directions to produce movement of the first shaft and adjust the length of the balloon.
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公开(公告)号:US20200229921A1
公开(公告)日:2020-07-23
申请号:US16841100
申请日:2020-04-06
Applicant: Edwards Lifesciences Corporation
Inventor: Walter Lee , Mark M. Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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公开(公告)号:US20190125532A1
公开(公告)日:2019-05-02
申请号:US16220385
申请日:2018-12-14
Applicant: Edwards Lifesciences Corporation
Inventor: Walter Lee , Mark Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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公开(公告)号:US20200060822A1
公开(公告)日:2020-02-27
申请号:US16668315
申请日:2019-10-30
Applicant: Edwards Lifesciences Corporation
Inventor: Thanh Huy Le , Tri D. Tran , Ronaldo C. Cayabyab , David M. Taylor , Antonio O. Vidal , Robert Bowes , Tram Ngoc Nguyen , Walter Lee
Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
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公开(公告)号:US20150342735A1
公开(公告)日:2015-12-03
申请号:US14827172
申请日:2015-08-14
Applicant: Edwards Lifesciences Corporation
Inventor: Walter Lee , Mark Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
IPC: A61F2/24
CPC classification number: A61F2/2433 , A61F2/958 , A61F2002/485 , A61F2002/9517 , A61F2002/9586 , A61F2250/0003 , A61F2250/0021 , A61M25/1002 , A61M25/10184 , A61M2025/1013 , A61M2025/1084
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
Abstract translation: 本文描述的是从假体装置(例如假体心脏瓣膜)传递穿过身体并进入心脏以植入其中的系统和方法。 与本文公开的递送系统一起递送的假体装置例如可以从安装在输送系统上的径向压缩状态径向展开,以便使用输送系统的可充气气囊进行植入。 通过身体和心脏的示例性递送途径包括经股动脉途径,经皮途径和经主动脉途径等。
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公开(公告)号:US20130345798A1
公开(公告)日:2013-12-26
申请号:US13922129
申请日:2013-06-19
Applicant: Edwards Lifesciences Corporation
Inventor: Teodoro S. Jimenez , Walter Lee , Mark Dehdashtian , Kristopher J. Yee
IPC: A61F2/24
CPC classification number: A61F2/2427 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2220/0016 , A61F2220/005 , A61M25/0133 , A61M25/0136 , A61M25/0138 , A61M25/0141 , A61M25/0144 , A61M25/0147 , A61M2025/015
Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic annulus in an antegrade fashion through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
Abstract translation: 用于将假体心脏瓣膜递送到主动脉瓣环的输送系统和方法。 该系统包括具有其上的转向机构的输送导管,用于通过穿过其顶点进入左心室的导引器以顺行方式将球囊可扩张的假体心脏瓣膜递送至主动脉环。 导引器可以具有比近端部分更软的远侧部分,以减少对心脏壁的创伤,同时保持良好的操作场稳定性。 输送导管包括刚好靠近远端气囊的偏转部分,以便于在主动脉瓣环内的正确取向中定位假体心脏瓣膜。 导管手柄中的触发器可以联接到致动偏转段的偏转线,而手柄中的滑块控制阀推动器的缩回。 假体心脏瓣膜可以安装在现有的钙化小叶上,并且还可以使用预扩张瓣膜成形术程序。
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公开(公告)号:US20240197469A1
公开(公告)日:2024-06-20
申请号:US18588420
申请日:2024-02-27
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Jensen Chen , Alison Louise Rodriguez , Walter Lee , Andrew Paul Schaffer
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2220/0008 , A61F2250/0098
Abstract: A docking station frame for a medical device includes a plurality of strut portions extending from a proximal end to a distal end and forming a plurality of cells. When the docking station frame is in an expanded, unconstrained condition, the plurality of strut portions form a substantially continuous concave longitudinal profile having outer radial retaining portions at the proximal end and the distal end and an inner radial central portion defining a seat.
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公开(公告)号:US20240115379A1
公开(公告)日:2024-04-11
申请号:US18542664
申请日:2023-12-16
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Walter Lee , Mark M. Dehdashtian , Teodoro S. Jimenez , Gilbert S. Leung , Bryan A. Janish , Michael G. Valdez , Tram Ngoc Nguyen , Timothy C. Ulrich
CPC classification number: A61F2/2433 , A61F2/958 , A61M25/10184
Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
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公开(公告)号:US20230380966A1
公开(公告)日:2023-11-30
申请号:US18231186
申请日:2023-08-07
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Thanh Huy Le , Tri D. Tran , Ronaldo C. Cayabyab , David M. Taylor , Antonio O. Vidal , Robert Bowes , Tram Ngoc Nguyen , Walter Lee
CPC classification number: A61F2/2433 , A61M25/01 , A61M25/10 , A61M25/1011 , A61M25/0147 , A61F2/2427 , A61F2/2418 , A61M25/0105 , A61M2025/0681
Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
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