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    Removal of microorganisms from fluid samples using nanofiber filtration media
    12.
    发明授权
    Removal of microorganisms from fluid samples using nanofiber filtration media 有权

    公开(公告)号：US10722602B2

    公开(公告)日：2020-07-28

    申请号：US16053523

    申请日：2018-08-02

    Applicant: EMD Millipore Corporation

    Inventor： Mikhail Kozlov ,  Wilson Moya ,  Gabriel Tkacik

    IPC: B01D39/16 ,  A61L2/00 ,  B01D67/00 ,  B01D69/00 ,  C02F1/44

    Abstract: A method for removing microorganisms from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid permeability and high microorganism retention. Microorganisms such as bacteria, particularly B. Diminuta, are removed from a liquid by passing the liquid through a porous nanofiber containing filtration medium having a B. Diminuta LRV greater than about 9, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. Another method for removing microorganisms such as bacteria and Mycloplasma, includes passing the liquid through a porous nanofiber containing filtration medium having a microorganism LRV greater than about 8, and the nanofiber(s) has a diameter from about 10 nm to about 1,000 nm. The filtration medium can be in the form of a fibrous electro spun polymeric nanofiber liquid filtration medium mat.

    Filter structure with enhanced dirt holding capacity
    18.
    发明授权
    Filter structure with enhanced dirt holding capacity 有权

    公开(公告)号：US12059644B2

    公开(公告)日：2024-08-13

    申请号：US15301781

    申请日：2015-06-23

    Applicant: EMD Millipore Corporation

    Inventor： Sal Giglia ,  David Nhiem ,  Sherry Ashby Leon ,  Gabriel Tkacik

    IPC: B01D39/16

    CPC classification number: B01D39/1623 ,  B01D2239/025 ,  B01D2239/0631 ,  B01D2239/065

    Abstract: A fluid filtration device containing a composite filter media having a coarse porous polymeric nonwoven interlayer located between first and second polymeric fiber containing filter mats. The fiber diameters of the fibers in the first and second filter mats are different from each other, and each filter mat has a different pore size rating. The first and second polymeric fibers in the filter mats can be electrospun nanofibers. The interlayer has a coarser pore size when compared to the either the first or second filter mats, such that the resulting composite media has an increased dirt holding capacity compared to filter layers that are layered directly over each other without the presence of a coarse interlayer therebetween.

    Enhanced aerosol test for assessing filter integrity
    20.
    发明授权
    Enhanced aerosol test for assessing filter integrity 有权

    公开(公告)号：US10151679B2

    公开(公告)日：2018-12-11

    申请号：US15057641

    申请日：2016-03-01

    Applicant: EMD Millipore Corporation

    Inventor： Salvatore Giglia ,  David Nhiem ,  Gabriel Tkacik

    IPC: G01N15/08 ,  B01D65/10 ,  G01M3/20

    Abstract: A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 μm in diameter, and even as small as 2 μm in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.

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