公开(公告)号：US20200032243A1

公开(公告)日：2020-01-30

申请号：US16595278

申请日：2019-10-07

Applicant: Exosome Diagnostics, Inc.

Inventor： Johan Karl Olov SKOG ,  Daniel ENDERLE ,  Aparna RAMACHANDRAN ,  Haoheng YAN ,  Emily BERGHOFF ,  Tai-Fen WEI ,  Mikkel NOERHOLM

IPC: C12N15/10

Abstract: The invention provides novel methods and kits for isolating nucleic acids from biological samples, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, and for extracting nucleic acids from the microvesicles and/or from the biological samples.

公开(公告)号：US20160177401A1

公开(公告)日：2016-06-23

申请号：US14909916

申请日：2014-08-06

Applicant: EXOSOME DIAGNOSTICS, INC.

Inventor： Johan Karl Olov Skog ,  Mikkel NOERHOLM

IPC: C12Q1/68

CPC classification number: C12Q1/6886 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16

Abstract: The present invention relates generally to the field of biomarker analysis, particularly determining gene expression signatures from urine samples. The disclosure provides compositions, kits and methods for diagnosing a prostate disorder such as prostate cancer in a male subject.

Abstract translation: 本发明一般涉及生物标志物分析领域，特别是从尿液样品中确定基因表达特征。 本公开提供用于诊断男性受试者中前列腺障碍如前列腺癌的组合物，试剂盒和方法。