公开(公告)号：US20150174287A1

公开(公告)日：2015-06-25

申请号：US14635170

申请日：2015-03-02

Applicant: Ethicon, Inc.

Inventor： Daniel Steiger ,  Dennis D. Jamiolkowski ,  Modesto Erneta

IPC: A61L17/12 ,  B29C49/00 ,  B29C47/00 ,  C08J3/00 ,  B29C45/00

CPC classification number: A61L17/12 ,  A61B17/06166 ,  A61B17/064 ,  A61B2017/00004 ,  A61L17/005 ,  A61L27/26 ,  A61L27/54 ,  A61L2300/202 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2430/00 ,  B29C45/00 ,  B29C47/00 ,  B29C49/00 ,  B29L2031/753 ,  C08J3/005 ,  C08J2367/04 ,  C08J2467/04 ,  C08L67/04 ,  Y10T442/10 ,  Y10T442/3976 ,  Y10T442/40 ,  Y10T442/696

Abstract: Novel absorbable polymer blends are disclosed. The blends are useful for manufacturing medical devices having engineered degradation and breaking strength retention in vivo. The blends consist of a first absorbable polymeric component and a second absorbable polymeric component. The weight average molecular weight of the first polymeric component is higher than the weight average molecular weight of the second polymeric component. At least at least one of said components is at least partially end-capped by a carboxylic acid group. Further aspects are medical devices made therefrom.

Abstract translation: 公开了新颖的可吸收聚合物共混物。 该混合物可用于制造具有工程化降解和体内断裂强度保留的医疗装置。 共混物由第一可吸收聚合物组分和第二可吸收聚合物组分组成。 第一聚合物组分的重均分子量高于第二聚合物组分的重均分子量。 所述组分中的至少一种至少部分被羧酸基部分封端。 其他方面是由其制成的医疗装置。

公开(公告)号：US11058792B2

公开(公告)日：2021-07-13

申请号：US16021322

申请日：2018-06-28

Applicant: Ethicon, Inc.

Inventor： Dennis D. Jamiolkowski ,  Christopher DeFelice ,  Sasa Andjelic ,  Brian M. Kelly ,  Marc Wisnudel ,  Daniel Steiger ,  Gaoyuan Gavin Chen

IPC: A61L17/12 ,  A61L17/00 ,  A61L17/14 ,  C08G63/64 ,  A61B17/06 ,  C08G63/08 ,  A61B17/00

Abstract: Novel surgical sutures and novel medical devices made from novel semi-crystalline, glycolide-rich A-B-A triblock copolymers of glycolide and lactide, wherein said B-segment is a fully amorphous random copolymer of glycolide and lactide, for long term medical applications are disclosed. The novel polymer compositions are useful for long term absorbable surgical sutures, meshes and other medical devices, especially for patients with compromised healing. The novel sutures have improved properties and improved breaking strength retention, while still substantially absorbing within about a 120-day period post-implantation.

公开(公告)号：US20130315963A1

公开(公告)日：2013-11-28

申请号：US13833690

申请日：2013-03-15

Applicant: ETHICON, INC.

Inventor： Modesto Erneta ,  Daniel Steiger ,  Dennis D. Jamiolkowski

IPC: A61L17/12 ,  A61B17/06 ,  A61L17/00

Abstract: Novel absorbable polymer blends are disclosed. The blends are useful for manufacturing medical devices having engineered degradation and breaking strength retention in vivo. The blends consist of a first absorbable polymeric component and a second absorbable polymeric component. The weight average molecular weight of the first polymeric component is higher than the weight average molecular weight of the second polymeric component. At least at least one of said components is at least partially end-capped by a carboxylic acid group. Further aspects are medical devices made therefrom.

Abstract translation: 公开了新颖的可吸收聚合物共混物。 该混合物可用于制造具有工程化降解和体内断裂强度保留的医疗装置。 共混物由第一可吸收聚合物组分和第二可吸收聚合物组分组成。 第一聚合物组分的重均分子量高于第二聚合物组分的重均分子量。 所述组分中的至少一种至少部分被羧酸基部分封端。 其他方面是由其制成的医疗装置。