中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

13 records (took 0.018 seconds)

    High-glass transition temperature absorbable microspheres
    4.
    发明授权
    High-glass transition temperature absorbable microspheres 有权
    高玻璃化转变温度可吸收微球

    公开(公告)号：US09216142B2

    公开(公告)日：2015-12-22

    申请号：US14062229

    申请日：2013-10-24

    Applicant: Ethicon, Inc.

    Inventor： Dennis D. Jamiolkowski ,  Modesto Erneta ,  Robert DiLuccio

    IPC: A61K9/14 ,  A61L27/58 ,  A61L27/50 ,  A61K8/02 ,  A61K8/85 ,  A61L27/18 ,  A61K9/16

    CPC classification number: A61K8/025 ,  A61K8/85 ,  A61K9/1647 ,  A61K2800/412 ,  A61L27/18 ,  A61L27/50 ,  A61L27/58 ,  Y10T428/2982 ,  C08L67/04

    Abstract: Absorbable microspheres comprising a copolymer formed from greater than 80 to about 99 mole percent D,L-lactideg, L(−)-lactide, D(+)-lactide, or meso-lactide and combinations thereof, and about 1 to less than 20 mole percent of a different second monomer selected from the group consisting of p-dioxanone and trimethylene carbonate and combinations thereof, said microspheres having a particle size ranging from about 5 to 2000 microns. Also described herein are formulations comprising such absorbable microspheres.

    Abstract translation: 包含由大于80-约99摩尔％D，L-丙交酯，L（ - ） - 丙交酯，D（+） - 丙交酯或内消旋丙交酯及其组合形成的共聚物和约1至小于20的可吸收微球 摩尔百分比的选自对二恶烷酮和三亚甲基碳酸酯及其组合的不同的第二单体，所述微球具有约5至2000微米的粒度。 本文还描述了包含这种可吸收微球体的制剂。

    Absorbable Polymeric Blend Compositions with Precisely Controllable Absorption Rates, Processing Methods, and Dimensionally Stable Medical Devices Therefrom
    5.
    发明申请
    Absorbable Polymeric Blend Compositions with Precisely Controllable Absorption Rates, Processing Methods, and Dimensionally Stable Medical Devices Therefrom 审中-公开
    可吸收的具有精确控制吸收率的聚合物混合组合物，加工方法和尺寸稳定的医疗器械

    公开(公告)号：US20150148496A1

    公开(公告)日：2015-05-28

    申请号：US14548536

    申请日：2014-11-20

    Applicant: Ethicon, Inc.

    Inventor： Dennis D. Jamiolkowski ,  Daniel Steiger ,  Brian M. Kelly ,  Christopher DeFelice ,  Sasa Andjelic ,  Modesto Erneta

    IPC: A61L31/04 ,  A61L31/14

    CPC classification number: A61L31/041 ,  A61B17/06166 ,  A61B17/064 ,  A61B2017/00004 ,  A61L17/105 ,  A61L27/26 ,  A61L27/58 ,  A61L31/148 ,  C08L67/04 ,  C08L2205/03 ,  C08L2666/18

    Abstract: Novel absorbable polymeric blends are disclosed. The blends have a first absorbable polymer type that is a polylactide polymer or a copolymer of lactide and glycolide and a second absorbable polymer type that is poly(p-dioxanone), wherein the first absorbable polymer type or the second absorbable polymer type or the first absorbable polymer type and the second absorbable polymer type additionally comprise a first polymeric component and a second polymeric component. The first polymeric component has a higher weight average molecular weight than the second polymeric component and at least one of said components is at least partially end-capped by a carboxylic acid. The novel polymeric blends are useful for manufacturing medical devices having dimensional stability, having engineered degradation and breaking strength retention in vivo. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.

    Abstract translation: 公开了新颖的可吸收聚合物共混物。 共混物具有第一可吸收聚合物类型，其是聚丙交酯聚合物或丙交酯和乙交酯的共聚物，以及聚（对二恶烷酮）的第二可吸收聚合物类型，其中第一可吸收聚合物类型或第二可吸收聚合物类型或第一可吸收聚合物类型 可吸收聚合物类型和第二可吸收聚合物类型另外包含第一聚合物组分和第二聚合物组分。 第一聚合物组分具有比第二聚合物组分更高的重均分子量，并且至少一种所述组分至少部分地被羧酸封端。 新型聚合物共混物可用于制造具有尺寸稳定性，具有工程化降解和体内断裂强度保持性的医疗装置。 还公开了由这些新型聚合物共混物制成的新型可吸收医疗器件以及新颖的制造方法。

    Mechanically Strong Absorbable Polymeric Blend Compositions of Precisely Controllable Absorption Rates, Processing Methods, And Products Therefrom
    7.
    发明申请
    Mechanically Strong Absorbable Polymeric Blend Compositions of Precisely Controllable Absorption Rates, Processing Methods, And Products Therefrom 审中-公开
    机械强吸收聚合物混合组合物的精确控制吸收率，加工方法和产品

    公开(公告)号：US20130315963A1

    公开(公告)日：2013-11-28

    申请号：US13833690

    申请日：2013-03-15

    Applicant: ETHICON, INC.

    Inventor： Modesto Erneta ,  Daniel Steiger ,  Dennis D. Jamiolkowski

    IPC: A61L17/12 ,  A61B17/06 ,  A61L17/00

    Abstract: Novel absorbable polymer blends are disclosed. The blends are useful for manufacturing medical devices having engineered degradation and breaking strength retention in vivo. The blends consist of a first absorbable polymeric component and a second absorbable polymeric component. The weight average molecular weight of the first polymeric component is higher than the weight average molecular weight of the second polymeric component. At least at least one of said components is at least partially end-capped by a carboxylic acid group. Further aspects are medical devices made therefrom.

    Abstract translation: 公开了新颖的可吸收聚合物共混物。 该混合物可用于制造具有工程化降解和体内断裂强度保留的医疗装置。 共混物由第一可吸收聚合物组分和第二可吸收聚合物组分组成。 第一聚合物组分的重均分子量高于第二聚合物组分的重均分子量。 所述组分中的至少一种至少部分被羧酸基部分封端。 其他方面是由其制成的医疗装置。

Patent Agency Ranking