公开(公告)号：US20210379237A1

公开(公告)日：2021-12-09

申请号：US16895150

申请日：2020-06-08

Applicant: Ethicon, Inc.

Inventor： Sai Veruva ,  Jianguo Zhou ,  Joseph Vliet ,  Gerard Llanos

IPC: A61L15/22 ,  A61F13/00 ,  A61L15/44 ,  A61L15/42 ,  A61L15/64 ,  A61L15/32

Abstract: The present invention is directed to an absorbable hemostatic patch that utilizes a biocompatible fibrous, fabric substrate that is melt-blown and napped or loosened at the surface, with the substrate having a low-profile, high flexibility, strength and porosity that is suitable for coating cross-linkable active molecules and ultimately effective for use as a hemostat in situations of problematic bleeding.

公开(公告)号：US09351883B2

公开(公告)日：2016-05-31

申请号：US14707559

申请日：2015-05-08

Applicant: Ethicon, Inc.

Inventor： Aaron D. Pesnell ,  Gerard Llanos

IPC: A61F13/00 ,  B05D1/18 ,  B05D1/02

CPC classification number: A61F13/00995 ,  A61K38/363 ,  A61K38/4833 ,  A61L15/26 ,  A61L15/28 ,  A61L15/32 ,  A61L15/42 ,  A61L15/64 ,  A61L2300/418 ,  A61L2400/04 ,  B05D1/02 ,  B05D1/18 ,  C08L71/02 ,  A61K2300/00 ,  C08L1/28 ,  C08L67/04

Abstract: A hemostatic pad comprising a bioabsorbable scaffolding material; a lyophilized thrombin powder, a lyophilized fibrinogen powder, and a meltable binder powder, with all powders disposed on the bioabsorbable scaffolding material. A meltable binder such as PEG bonds the lyophilized thrombin powder and the lyophilized fibrinogen powder to the bioabsorbable scaffolding material for improved friability, wettability and performance in a use, such as for hemostatic treatment or sealing at a wound site.