公开(公告)号：US4492322A

公开(公告)日：1985-01-08

申请号：US373647

申请日：1982-04-30

申请人： Gary M. Hieftje ,  John Shabushnig

发明人： Gary M. Hieftje ,  John Shabushnig

IPC分类号： B01L3/02 ,  B67D5/00

CPC分类号： B01L3/0268

摘要： A device for accurately dispensing small volumes of liquids in the form of uniform droplets. The dispensing device communicates with a source of compressed air which, during start-up transience of the dispensing device, directs a jet of compressed air at the trajectory of dispensed droplets, thereby deflecting the droplets out of their normal trajectory and away from the collecting surface or container and allowing accurate dispensing.

摘要翻译： 用于精确分配均匀液滴形式的小体积液体的装置。 分配装置与压缩空气源连通，在分配装置的启动瞬态期间，在分配的液滴的轨迹处引导压缩空气流，从而使液滴偏离其正常轨迹并远离收集表面 或容器，并允许精确的分配。

公开(公告)号：US07768639B1

公开(公告)日：2010-08-03

申请号：US12212915

申请日：2008-09-18

申请人： George C. Y. Chan ,  Gary M. Hieftje

发明人： George C. Y. Chan ,  Gary M. Hieftje

IPC分类号： G01N21/73

CPC分类号： G01N21/73 ,  G01N21/274

摘要： A method for detecting and correcting inaccurate results in inductively coupled plasma-atomic emission spectrometry (ICP-AES). ICP-AES analysis is performed across a plurality of selected locations in the plasma on an unknown sample, collecting the light intensity at one or more selected wavelengths of one or more sought-for analytes, creating a first dataset. The first dataset is then calibrated with a calibration dataset creating a calibrated first dataset curve. If the calibrated first dataset curve has a variability along the location within the plasma for a selected wavelength, errors are present. Plasma-related errors are then corrected by diluting the unknown sample and performing the same ICP-AES analysis on the diluted unknown sample creating a calibrated second dataset curve (accounting for the dilution) for the one or more sought-for analytes. The cross-over point of the calibrated dataset curves yields the corrected value (free from plasma related errors) for each sought-for analyte.

摘要翻译： 一种在电感耦合等离子体原子发射光谱法（ICP-AES）中检测和校正不准确结果的方法。 在未知样品上的等离子体中的多个选定位置上进行ICP-AES分析，收集一种或多种所寻找分析物的一个或多个所选波长的光强度，从而产生第一数据集。 然后用校准数据集校准第一个数据集，创建校准的第一个数据集曲线。 如果校准的第一数据集曲线沿着所选波长的等离子体内的位置具有可变性，则存在错误。 然后通过稀释未知样品并对稀释的未知样品进行相同的ICP-AES分析来校正等离子体相关误差，产生针对一种或多种所寻找分析物的校准的第二数据集曲线（占稀释度）。 校准数据集曲线的交叉点产生每个寻找分析物的校正值（无等离子体相关误差）。

公开(公告)号：US5614711A

公开(公告)日：1997-03-25

申请号：US434931

申请日：1995-05-04

申请人： Gangqiang Li ,  Gary M. Hieftje

发明人： Gangqiang Li ,  Gary M. Hieftje

IPC分类号： B01D59/44 ,  H01J49/40 ,  H01J49/00

CPC分类号： H01J49/40 ,  B01D59/44

摘要： A novel, time-of-flight mass spectrometer for the qualitative and quantitative analysis of elemental, molecular, and isotopic chemical samples is provided which offers increased sensitivity, speed of analysis, resolving power, and signal-to-noise ratios than prior mass spectrometers by properly sampling and collimating an ion beam from a continuous ion source, decelerating said ion, forming ion packets from the continuous ion beam, storing said ion packets, extracting and accelerating the ion packets along a stable flight path, transversely compressing said packets, focusing ions of similar mass, and detecting the focused ion masses. The mass spectrometer includes an ion optics assembly and an analyzer disposed along a common axis coincident with a continuous beam of sampled ions. The relationship between the ion extractor and accelerator are such that ions of isomass are focused at at least one point in space in the analyzer along a narrow flight path so as to be either removed from the flight path or allowed to proceed and be detected at substantially the same time. The separate modulation and extraction steps, when coupled with the space-focusing and selected deflection of certain ionic species, results in higher sensitivity, greater analysis speed, higher resolving power, and improved signal-to-noise ratio than achieved in prior orthogonal or on-axis time-of-flight mass spectrometers. A novel method achieved by the apparatus is also disclosed.

摘要翻译： 提供了一种用于元素，分子和同位素化学样品的定性和定量分析的新型飞行时间质谱仪，其提供了比现有的质谱仪更高的灵敏度，分析速度，分辨率和信噪比 通过适当地对来自连续离子源的离子束进行采样和准直，使所述离子减速，从连续离子束形成离子包，存储所述离子包，沿着稳定的飞行路径提取和加速离子包，横向压缩所述包，聚焦 离子质量相似，并检测聚焦离子质量。 质谱仪包括离子光学组件和沿着与连续的取样离子束重合的共同轴设置的分析仪。 离子提取器和加速器之间的关系使得等离子体的离子沿着窄的飞行路径聚焦在分析仪中的空间中的至少一个点处，以便从飞行路径移除或允许进行并基本上被检测 同一时间。 单独的调制和提取步骤当与某些离子物质的空间聚焦和选择的偏转相结合时，导致比在先前的正交或在之前实现的更高的灵敏度，更高的分析速度，更高的分辨能力和改善的信噪比 -axis飞行时间质谱仪。 还公开了一种由该装置实现的新颖方法。

公开(公告)号：US5335860A

公开(公告)日：1994-08-09

申请号：US1815

申请日：1993-01-08

申请人： Gary M. Hieftje ,  Min Wu

发明人： Gary M. Hieftje ,  Min Wu

IPC分类号： G01N21/71 ,  B05B1/34

CPC分类号： G01N21/714

摘要： Described is a preferred rotary spray chamber device for conditioning an aerosol. The device has chamber walls defining an internal chamber and an inlet opening into the internal chamber. The inlet opening is located such that an aerosol directed into the chamber through the inlet opening tangentially contacts chamber wall areas adapted to impart a rotary motion to the aerosol within the chamber. An impact member extends inwardly into the chamber from a chamber wall location such that the member is impacted by the aerosol in its rotary motion so as to remove large droplets and thus form a conditioned aerosol. An exit opening is defined by the chamber walls through which the conditioned aerosol can exit the chamber, and a drain opening is also defined by the chamber walls through which liquid removed from the aerosol and collected in the chamber can exit the chamber.

摘要翻译： 描述了用于调节气溶胶的优选旋转喷雾室装置。 该装置具有限定内部室的室壁和通向内部室的入口。 入口开口被定位成使得通过入口开口引导到室中的气雾剂切向地接触适于向室内的气溶胶施加旋转运动的室壁区域。 冲击构件从室壁位置向内延伸到室中，使得构件在其旋转运动中被气溶胶撞击，以便去除大液滴并因此形成调节气溶胶。 出口开口由室壁限定，经调节的气溶胶可以通过室壁离开室，并且排出口也由室壁限定，通过该室壁，从气溶胶移出并收集在室中的液体可以从室壁离开室。

公开(公告)号：US4800279A

公开(公告)日：1989-01-24

申请号：US776133

申请日：1985-09-13

申请人： Gary M. Hieftje ,  David E. Honigs ,  Thomas B. Hirschfeld

发明人： Gary M. Hieftje ,  David E. Honigs ,  Thomas B. Hirschfeld

IPC分类号： G01N21/35 ,  G01N33/28 ,  G01J1/00

CPC分类号： G01N33/2829 ,  G01N21/359 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/3577

摘要： Methods are disclosed for quantifying physical properties of gaseous, liquid or solid samples. The near-infrared absorbance spectra of a representative field of calibration samples are measured and recorded using a spectrophotometer. The absorbance spectra of the calibration samples are evaluated by a row-reduction algorithm to determine which wavelengths in the near-infrared spectrum, and associated weighting constants, are statistically correlated to the physical property being quantified. The near-infrared absorbance of actual samples is then measured at each of the correlated wavelengths, and then corrected by the corresponding weighting constants. A reference value for the physical property being quantified is then computed from the corrected measure of the absorbance of the sample at each of the correlated wavelengths.

摘要翻译： 公开了用于量化气态，液态或固态样品的物理性质的方法。 使用分光光度计测量和记录校准样品的代表性场的近红外吸收光谱。 校准样品的吸收光谱通过行减法算法进行评估，以确定近红外光谱中的哪些波长和相关联的加权常数与被量化的物理性质统计相关。 然后在每个相关波长处测量实际样品的近红外吸光度，然后通过相应的加权常数进行校正。 然后根据每个相关波长处的样品的吸光度的校正测量来计算待量化的物理性质的参考值。

公开(公告)号：US07929138B1

公开(公告)日：2011-04-19

申请号：US12336679

申请日：2008-12-17

申请人： Michael R. Webb ,  Gary M. Hieftje ,  Francisco Andrade

发明人： Michael R. Webb ,  Gary M. Hieftje ,  Francisco Andrade

IPC分类号： G01N21/00

CPC分类号： G01N21/67

摘要： An ambient atmosphere glow discharge spectrometer is disclosed having a capillary, two electrodes and a means for recording the atomic emissions.

摘要翻译： 公开了具有毛细管，两个电极和用于记录原子发射的装置的环境气氛辉光放电光谱仪。

公开(公告)号：US4642778A

公开(公告)日：1987-02-10

申请号：US585575

申请日：1984-03-02

申请人： Gary M. Hieftje ,  David H. Honigs

发明人： Gary M. Hieftje ,  David H. Honigs

IPC分类号： G01J3/28 ,  G01N21/35 ,  G06F15/46

CPC分类号： G01J3/28 ,  G01N21/3577 ,  G01J2003/284 ,  G01J2003/2866

摘要： A method is presented for spectral reconstruction which comprises first obtaining component concentrations of a series of mixtures, which component concentrations constitute a set of reference values. The spectral value of each member of that series of mixtures is measured at a first wavelength, which spectral value possesses contribution from individual components in the mixture, whose individual contribution is unknown. The spectral values for the series of mixtures are then mathematically cross-correlated with the component concentrations in said series of mixtures, at the first wavelength, thereby obtaining the spectral contribution for said components at that first wavelength. The spectral value of each member of that series of mixtures is measured at the second wavelength, which spectral values are then cross-correlated with component concentrations in the series of mixtures thereby obtaining the spectral contribution for said components at the second wavelength. This operation is repeated for a series of wavelengths until the spectrum of the desired component in the mixture is reconstructed. Devices are presented which implement the methods for spectral reconstruction of the present invention.

摘要翻译： 提出了一种用于光谱重建的方法，其包括首先获得一系列混合物的组分浓度，该组分浓度构成一组参考值。 该系列混合物的每个成员的光谱值在第一波长处测量，该光谱值具有来自混合物中各个成分的贡献，其个体贡献是未知的。 然后，该系列混合物的光谱值在第一波长处与所述混合物系列中的组分浓度数学上交叉相关，由此获得在该第一波长处的所述组分的光谱贡献。 在第二波长处测量该系列混合物的每个成员的光谱值，该光谱值然后与该系列混合物中的成分浓度交叉相关，从而获得第二波长处的所述成分的光谱贡献。 对于一系列波长重复该操作，直到重构混合物中所需组分的光谱。 给出了实现本发明的光谱重建方法的装置。

公开(公告)号：US4462685A

公开(公告)日：1984-07-31

申请号：US240542

申请日：1981-03-04

申请人： Stanley B. Smith, Jr. ,  Gary M. Hieftje

发明人： Stanley B. Smith, Jr. ,  Gary M. Hieftje

IPC分类号： G01N21/31

CPC分类号： G01N21/3103

摘要： An atomic absorption system comprising a radiation source that emits spectral line radiation characteristic of an element to be analyzed, an analysis region open to passage of the beam of radiation from the source and in which a sample of the substance to be analyzed is atomized, source control means for alternately energizing the source at a first intensity level to provide a radiation output that has a narrow spectral line at a wavelength of an element to be detected and at a higher intensity level to provide a radiation output of broader wavelength with intensity suppression at the wavelength of the narrow spectral line, electronic transducing means for developing an electrical signal corresponding to the sensed radiation intensity of the radiation beam that passes through the analysis region, and a log ratio circuit that utilizes integrated electrical signals corresponding to the two source energization intensity levels to provide background corrected concentration information on the element of interest in the analyzed sample.

摘要翻译： 一种原子吸收系统，包括发射待分析元件的光谱线辐射特性的辐射源，对来自源的辐射束通过的分析区域，待分析物质的样品被雾化， 控制装置，用于以第一强度水平交替地激励源，以提供在要被检测的元件的波长处具有窄谱线的辐射输出，并且处于较高的强度水平，以提供具有强度抑制的较宽波长的辐射输出 窄谱线的波长，用于产生对应于通过分析区域的辐射束的感测辐射强度的电信号的电子传感装置，以及利用对应于两个源通电强度的集成电信号的对数比电路 在t上提供背景校正浓度信息的级别 他在分析的样本中感兴趣的元素。