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11.Anti-PCSK9 antibodies, formulations, dosing, and methods of use 有权
Title translation: 抗PCSK9抗体,配方,给药和使用方法公开(公告)号:US09266961B2
公开(公告)日:2016-02-23
申请号:US13918755
申请日:2013-06-14
Applicant: Genentech, Inc.
Inventor: Yan Wu , Cecilia Pui Chi Chiu , Daniel K. Kirchhofer , Andrew Peterson , Ganesh A. Kolumam , Monica Kong Beltran , Paul Moran , Wei Li , Xanthe M. Lam , Lin Luis , Ada Hui
IPC: C07K16/40 , A61K39/395 , A61K39/00
CPC classification number: C07K16/40 , A61K39/39591 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides anti-PCSK9 antibodies, formulations, dosing regimens, and methods of using the same.
Abstract translation: 本发明提供抗PCSK9抗体,制剂,给药方案及其使用方法。
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公开(公告)号:US08969528B2
公开(公告)日:2015-03-03
申请号:US13765625
申请日:2013-02-12
Applicant: Genentech, Inc.
Inventor: Daniel K. Kirchhofer , Yan Wu
CPC classification number: C07K16/22 , C07K16/32 , C07K16/40 , C07K2317/21 , C07K2317/24 , C07K2317/54 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides methods and compositions for modulating hepatocyte growth factor activator function.
Abstract translation: 本发明提供调节肝细胞生长因子激活功能的方法和组合物。
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公开(公告)号:US20140212431A1
公开(公告)日:2014-07-31
申请号:US14133986
申请日:2013-12-19
Applicant: Genentech, Inc.
Inventor: Daniel K. Kirchhofer , Yingnan Zhang , Andrew Scott Peterson , Wei Li , Monica Kong-Beltran , Lijuan Zhou
IPC: C07K16/40 , A61K45/06 , A61K39/395
CPC classification number: C07K16/40 , A61K31/40 , A61K38/1808 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2300/00 , C07K14/485 , C07K2317/70 , C07K2319/30 , C12N9/6454 , A61K31/22 , A61K31/365 , A61K31/366 , A61K31/404 , A61K31/505
Abstract: The invention provides PCSK9-binding polypeptides and methods of using the same.
Abstract translation: 本发明提供PCSK9结合多肽及其使用方法。
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公开(公告)号:US20190054138A1
公开(公告)日:2019-02-21
申请号:US15921827
申请日:2018-03-15
Applicant: Genentech, Inc.
Inventor: Daniel K. Kirchhofer , Robert A. Lazarus , Xiaoyi Yao
IPC: A61K38/10 , G01N33/68 , G01N33/574 , C07K7/08 , C07K14/475 , G01N33/74
Abstract: The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by regulating binding of HGF β chain to c-met.
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15.
公开(公告)号:US20130217862A1
公开(公告)日:2013-08-22
申请号:US13765625
申请日:2013-02-12
Applicant: Genentech, Inc.
Inventor: Daniel K. Kirchhofer , Yan Wu
IPC: C07K16/22
CPC classification number: C07K16/22 , C07K16/32 , C07K16/40 , C07K2317/21 , C07K2317/24 , C07K2317/54 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides methods and compositions for modulating hepatocyte growth factor activator function.
Abstract translation: 本发明提供调节肝细胞生长因子激活功能的方法和组合物。
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