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公开(公告)号：US10882920B2
公开(公告)日：2021-01-05
申请号：US15525791
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC: C07K16/40 , A61K47/68 , A61K39/00 , G01N33/573
Abstract: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders.
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公开(公告)号：US20180057604A1
公开(公告)日：2018-03-01
申请号：US15525821
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan WU , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
CPC classification number: C07K16/40 , A61K2039/505 , C07K16/22 , C07K16/2881 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C12Y304/23046 , G01N33/6896 , G01N2333/70582 , G01N2333/96472 , G01N2800/28 , G01N2800/52
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号：US20210206877A1
公开(公告)日：2021-07-08
申请号：US17113711
申请日：2020-12-07
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus
IPC: C07K16/40 , A61K47/68 , G01N33/573
Abstract: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders
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公开(公告)号：US20170058049A1
公开(公告)日：2017-03-02
申请号：US15234649
申请日：2016-08-11
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
Abstract translation: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号：US20230303682A1
公开(公告)日：2023-09-28
申请号：US18004550
申请日：2021-07-16
Applicant: Genentech, Inc.
Inventor： Cecilia Pui Chi Chiu , Yan Wu , Adel Mahmoud ElSohly , Daniel George Lafkas , Jian Mehr-Dean Payandeh , Hoangdung Dang Ho , Siao-Ping Tsai
IPC: C07K16/28 , A61K45/06 , A61K39/395 , A61P11/00
CPC classification number: C07K16/28 , A61K39/3955 , A61K45/06 , A61P11/00 , C07K2317/24 , C07K2317/34 , C07K2317/35 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-Notch2 antibodies and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US09879094B2
公开(公告)日：2018-01-30
申请号：US15234649
申请日：2016-08-11
Applicant: Genentech, Inc.
Inventor： Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC: C07H21/04 , C07K16/18 , C12P21/08 , C07K16/40 , A61K39/395 , G01N33/573 , C12P21/00 , A61K47/68 , A61K39/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
Abstract: The invention provides antibodies to specific neural proteins and methods of using the same.
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公开(公告)号：US09266961B2
公开(公告)日：2016-02-23
申请号：US13918755
申请日：2013-06-14
Applicant: Genentech, Inc.
Inventor： Yan Wu , Cecilia Pui Chi Chiu , Daniel K. Kirchhofer , Andrew Peterson , Ganesh A. Kolumam , Monica Kong Beltran , Paul Moran , Wei Li , Xanthe M. Lam , Lin Luis , Ada Hui
IPC: C07K16/40 , A61K39/395 , A61K39/00
CPC classification number: C07K16/40 , A61K39/39591 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The invention provides anti-PCSK9 antibodies, formulations, dosing regimens, and methods of using the same.
Abstract translation: 本发明提供抗PCSK9抗体，制剂，给药方案及其使用方法。
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8.发明公开公开(公告)号：US20240084042A1
公开(公告)日：2024-03-14
申请号：US18464580
申请日：2023-09-11
Applicant: Genentech, Inc.
Inventor： James Thomas Koerber , Wyne Pun Lee , Tangsheng Yi , Juan Zhang , Cary Dean Austin , Cecilia Pui Chi Chiu , Joseph Edward Chavarria-Smith , Jawahar Sudhamsu
CPC classification number: C07K16/468 , A61P29/00 , C07K2317/14 , C07K2317/31 , C07K2317/565
Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.
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公开(公告)号：US11008403B2
公开(公告)日：2021-05-18
申请号：US15525821
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan Wu , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号：US20160368994A1
公开(公告)日：2016-12-22
申请号：US15182327
申请日：2016-06-14
Applicant: Genentech, Inc.
Inventor： Robert F. Kelley , Steven R. Leong , Wei-Ching Liang , Mary Mathieu , Andrew G. Polson , Bing Zheng , Xiaocheng Chen , Cecilia Pui Chi Chiu , Mark S. Dennis , Allen Ebens , Yan Wu
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2851 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/57 , C07K16/2803 , C07K16/2809 , C07K16/2827 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/52 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/90 , C07K2317/92 , C07K2317/94
Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
Abstract translation: 本发明涉及包含CLL-1结合结构域和CD3结合结构域（例如，抗CLL-1 / CD3T细胞依赖性双特异性（TDB）抗体）的抗CLL-1抗体的抗CLL-1抗体， 使用方法
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