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公开(公告)号:US20150132218A1
公开(公告)日:2015-05-14
申请号:US14518294
申请日:2014-10-20
Applicant: Genentech, Inc.
Inventor: Jyoti Asundi , Ron Firestein , Paul Polakis , Chie Sakanaka , Peter Chang , Rayna Takaki Venook
IPC: C07K16/30 , A61K51/10 , G01N33/574 , A61K47/48
CPC classification number: C07K16/30 , A61K47/6803 , A61K47/6851 , A61K51/1045 , A61K2039/505 , C07K2317/34 , G01N33/574 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57438 , G01N33/57446 , G01N33/57449 , G01N33/57492 , G01N2333/705
Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗Ly6E抗体,免疫缀合物及其使用方法。
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公开(公告)号:US20130217014A1
公开(公告)日:2013-08-22
申请号:US13769105
申请日:2013-02-15
Applicant: GENENTECH, INC.
Inventor: Ron Firestein , Adam Shultz
CPC classification number: G01N33/5073 , C12N5/0606 , C12N5/0695 , C12N2501/405 , C12Q1/6886 , G01N2333/9121
Abstract: Provided herein are CDK8 antagonists and methods of using the same.
Abstract translation: 本文提供CDK8拮抗剂及其使用方法。
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公开(公告)号:US10889651B2
公开(公告)日:2021-01-12
申请号:US16050936
申请日:2018-07-31
Applicant: Genentech, Inc.
Inventor: Jyoti Asundi , Ron Firestein , Paul Polakis , Chie Sakanaka , Peter Chang , Rayna Takaki Venook
IPC: C07K16/30 , G01N33/574 , A61K47/68 , A61K51/10 , A61K39/00
Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same.
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公开(公告)号:US20190248889A1
公开(公告)日:2019-08-15
申请号:US16390757
申请日:2019-04-22
Applicant: GENENTECH, INC.
Inventor: Andrew G. Polson , Weiguang Mao , Ron Firestein
IPC: C07K16/28 , G01N33/574 , C07K16/30
CPC classification number: C07K16/28 , A61K39/39558 , A61K2039/5152 , C07K16/3046 , C07K2317/56 , C07K2317/565 , C07K2317/70 , G01N33/574 , G01N33/57492 , G01N2800/52
Abstract: The invention provides anti-LgR5 antibodies and methods of using the same.
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公开(公告)号:US10059768B2
公开(公告)日:2018-08-28
申请号:US14851003
申请日:2015-09-11
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574 , A61K47/68
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US09815905B2
公开(公告)日:2017-11-14
申请号:US14500079
申请日:2014-09-29
Applicant: Genentech, Inc.
Inventor: Paul Polakis , Jyoti Asundi , Ron Firestein , Robert F. Kelley , Krista McCutcheon
CPC classification number: C07K16/30 , A61K31/40 , A61K39/39558 , A61K47/6803 , A61K47/6851 , A61K51/1045 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/732 , C07K2317/77 , C07K2317/92 , G01N33/6854
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20160159910A1
公开(公告)日:2016-06-09
申请号:US14851003
申请日:2015-09-11
Applicant: GENENTECH, INC.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K31/5517 , A61K31/706 , G01N33/574 , A61K47/48 , C07K16/22 , A61K51/10 , A61K38/05 , A61K31/404
CPC classification number: C07K16/2827 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , A61K47/6803 , A61K47/6809 , A61K47/6855 , A61K47/6869 , A61K2039/505 , C07K16/3015 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20160017040A1
公开(公告)日:2016-01-21
申请号:US14773334
申请日:2014-03-13
Applicant: GENENTECH, INC.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/48 , G01N33/569 , A61K39/395 , A61K51/10 , C07K16/30 , A61K38/08
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本公开提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20150023871A1
公开(公告)日:2015-01-22
申请号:US14500079
申请日:2014-09-29
Applicant: Genentech, Inc.
Inventor: Paul Polakis , Jyoti Asundi , Ron Firestein , Robert F. Kelley , Krista McCutcheon
CPC classification number: C07K16/30 , A61K31/40 , A61K39/39558 , A61K47/6803 , A61K47/6851 , A61K51/1045 , A61K2039/505 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/732 , C07K2317/77 , C07K2317/92 , G01N33/6854
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20220251213A1
公开(公告)日:2022-08-11
申请号:US17677283
申请日:2022-02-22
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/68 , C07K16/30 , A61K31/404 , A61K31/5517 , A61K31/706 , A61K38/05 , G01N33/574
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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