摘要:
Pharmaceutical compositions containing a non-steroidal anti-inflammatory compound and 5,11-dihydro-11-[(4-methyl-1-piperazinyl)-acetyl]-6H-pyrido[2,3-b]-[1,4]benzodiazepin-6-one or a non-toxic acid addition salt thereof, and a method of using the same as antiphlogistics; the pyridobenzodiazepinone ingredient effectively suppresses the gastro-intestinal side-effects of the anti-inflammatory ingredient.
摘要:
Pharmaceutical compositions are described which contain 1,5,6,7-tetrahydro-4H-indazol-4-ones of the formula ##STR1## some of these substances themselves being new. The pharmaceutical compositions may be used as analgesics, antipyretics and antiphlogistics.
摘要:
The invention relates to the separation of enantiomers of cimaterol, (-)-cimaterol, the addition salts thereof and processes for preparing them and their use in pharmaceutical compositions and animal feeds.
摘要:
A printed sheet delivery device (3) for a printing station (1) includes a collection tray (7) reciprocatable by a transverse-displacement drive (6) for receiving and sorting sheets (2) in stacked, printed-side-down relation in transversely staggered groups (4a). A housing (9) separate from and releasably securable to the printing station (1) is formed of a lower housing part (9a) within which the transverse-displacement drive (6) is mounted and an upper housing part (9b) that is contoured to define the collection tray (7). Slide guides (14a, 14b) carried on the bottom (13) of the upper housing part (9b) on both sides transverse to the direction (5) of sheet delivery cooperate with guide ledges (25, 26) on the lower housing part (9a) for guided transverse reciprocation of the upper housing part relative to the lower housing part.
摘要:
Compounds of the formula ##STR1## wherein R.sub.1 --is hydrogen, alkyl of 1 to 6 carbon atoms or benzyl;R.sub.2 --is alkyl of 1 to 6 carbon atoms, cycloalkyl of 5 to 7 carbon atoms or, together with R.sub.1 and the adjacent nitrogen atom, pyrrolidino, piperidino, hexamethyleneimino, morpholino or N'-methyl-piperazino, where each of the heterocycles may have one or two alkyl of 1 to 3 carbon atoms or one or two methoxy substituents attached thereto;R.sub.3,--r.sub.4 and R.sub.5 are each hydrogen or methyl;R.sub.6 --is alkyl of 1 to 4 carbon atoms; andA--is alkylene of 2 to 4 carbon atoms;And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as bronchospasmolytics and bronchosecretolytics.
摘要:
Compounds of the formula formula ##EQU1## wherein R.sub.1 is chlorine or fluorine, and R.sub.2 is hydrogen, alkanoyl of 1 to 10 carbon atoms, benzoyl, nicotinoyl or isonicotinoyl,Or, when R.sub.2 contains a basic nitrogen atom, a non-toxic, pharmacologically acceptable salt thereof formed with an inorganic or organic acid; the compounds as well as the salts are useful as antiphlogistics.
摘要:
There are described pharmaceutical compositions containing as active substances benzothiazol-2(3H)-ones of the general formula ##STR1## wherein R represents a hydrogen atom or a methyl, methoxy, or ethoxy group. The pharmaceutical compositions serve as analgesics and antipyretics and possess little or no methemoglobin-forming activity.
摘要:
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen or alkyl of 1 to 3 carbon atoms; R.sub.2 is hydrogen or alkyl of 1 to 3 carbon atoms; andR.sub.3 is aromatic hydrocarbyl of 6 to 10 carbon atoms or an aromatic heterocycle of 2 to 9 carbon atoms and 1 to 2 nitrogen atoms and/or an oxygen or a sulfur atom, where each of said aromatic substituents may in turn be substituted with one or two alkyls of 1 to 6 carbon atoms, halogen, hydroxyl, trifluoromethyl, halophenyl or alkoxy of 1 to 3 carbon atoms;and non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases; the compounds as well as their salts are useful as analgesics, antipyretics, antithrombotic and antiphlogistics.
摘要:
Pharmaceutical compositions containing a non-steroidal anti-inflammatory compound and 5,11-dihydro-11-[(4-methyl-1-piperazinyl)-acetyl]-6H-pyrido[2,3-b]-[1,4]benzodiazepin-6-one or a non-toxic acid addition salt thereof, and a method of using the same as antiphlogistics; the pyridobenzodiazepinone ingredient effectively suppresses the gastro-intestinal side-effects of the anti-inflammatory ingredient.