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    NANOCRYSTALS WITH FUNCTIONAL LIGANDS
    11.
    发明申请
    NANOCRYSTALS WITH FUNCTIONAL LIGANDS 有权
    具有功能配置的纳米晶体

    公开(公告)号：US20110256404A1

    公开(公告)日：2011-10-20

    申请号：US13122094

    申请日：2009-09-30

    申请人： Eric Tulsky ,  Eric Welch ,  Bruce Branchaud ,  Roman Rozhkov

    发明人： Eric Tulsky ,  Eric Welch ,  Bruce Branchaud ,  Roman Rozhkov

    IPC分类号： B32B5/16 ,  C07F9/38

    CPC分类号： C09K11/025 ,  C09K11/883 ,  Y10T428/2998

    摘要： Coated fluorescent semiconductor nanoparticles having an organic surface layer of multi-functional surface ligands that include a nanocrystal binding center and one or more covalently attached functional groups or reactive functional groups are described as well as water-dispersible nanoparticles having an organic surface layer or multi-functional surface ligands and methods for the preparation and use of such coated nanoparticles.

    摘要翻译： 描述了具有包括纳米晶体结合中心和一个或多个共价连接的官能团或反应性官能团的多功能表面配体的有机表面层的涂覆的荧光半导体纳米颗粒以及具有有机表面层或多层结构的水分散性纳米颗粒， 功能性表面配体和用于制备和使用这种包被的纳米颗粒的方法。

    COMPOSITIONS AND METHODS FOR STABILIZING SUSCEPTIBLE COMPOUNDS
    15.
    发明申请
    COMPOSITIONS AND METHODS FOR STABILIZING SUSCEPTIBLE COMPOUNDS 审中-公开
    用于稳定可疑化合物的组合物和方法

    公开(公告)号：US20130316004A1

    公开(公告)日：2013-11-28

    申请号：US13984263

    申请日：2012-02-07

    申请人： Richard Fike ,  Bruce Branchaud ,  Shawn Barrett

    发明人： Richard Fike ,  Bruce Branchaud ,  Shawn Barrett

    IPC分类号： C12N5/00

    摘要： Methods for increasing the stability of, or protecting, labile components such as ethanolamine, growth factors, vitamins, etc., in compositions such as a cell culture medium. Stability of the labile compound is increased either, by derivatization of the labile compound with chemicals, or by sequestering the labile compound. Sequestering can be done either by encapsulation within a microcapsule, or by the use of sequestering agents. Encapsulation includes the encapsulation of dendrimers complexes of susceptible compounds within the microcapsule, thereby providing the controlled release of the susceptible compound that was protected.These methods may improve and extend storage conditions of compositions comprising the labile compounds, improve shipping and handling of compositions comprising the labile compounds, such as dry media formulations, at room temperature rather than at lower temperatures thereby decreasing shipping costs. Stabilization of labile compounds in compositions such as dry format media can be viewed as a contribution to green technology.

    摘要翻译： 在诸如细胞培养基的组合物中增加不稳定组分如乙醇胺，生长因子，维生素等的稳定性或保护的方法。 不稳定化合物的稳定性也通过不稳定化合物与化学品的衍生化或通过螯合不稳定化合物而增加。 螯合可以通过在微胶囊内包封或通过使用螯合剂进行。 封装包括在微胶囊中包封易感化合物的树枝状大分子复合物，从而提供受保护的易感化合物的受控释放。 这些方法可以改善和延长包含不稳定化合物的组合物的储存条件，改善运送和处理包含不稳定化合物（例如干燥介质制剂）的组合物，而不是在较低的温度下降低运输成本。 不稳定化合物在组合物如干式培养基中的稳定可被视为对绿色技术的贡献。