公开(公告)号：US11154637B2

公开(公告)日：2021-10-26

申请号：US16675860

申请日：2019-11-06

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Hsin-Hsin Shen ,  Yu-Chi Wang ,  Sen-Lu Chen ,  Yu-Bing Liou ,  Jian-Wei Lin ,  Yi-Hsuan Lee ,  Ming-Chia Yang ,  Ying-Wen Shen ,  Wei-Lin Yu

IPC: A61L24/06 ,  A61L24/00

Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.

公开(公告)号：US11027040B2

公开(公告)日：2021-06-08

申请号：US15855694

申请日：2017-12-27

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Hsin-Hsin Shen ,  Ming-Chia Yang ,  Chia-Chi Ho ,  Fang-Jie Jang ,  Che-Yu Ou ,  Chi-Hsiang Liao ,  Brian Hsu ,  Tai-Horng Young

IPC: A61L24/00 ,  A61L24/04

Abstract: The present disclosure provides a method for manufacturing a porous film, including: preparing a polymer mixture solution, wherein the polymer mixture solution includes polycaprolactone and at least one hydrophobic polymer; adding solid particles as a dispersing agent to the polymer mixture solution and mixing the solid particles with the polymer mixture solution, wherein the amount of solid particles added is enough to convert the polymer mixture solution into a solid mixture; drying the solid mixture to form a film; and washing the film with a washing fluid to remove the solid particles from the film to form the porous film, wherein the weight ratio of the polycaprolactone to the at least one hydrophobic polymer is about 1:0.1-10, and wherein the weight ratio of the polycaprolactone and the at least one hydrophobic polymer to the solid particles is about 1:0.01-250.

公开(公告)号：US20190201203A1

公开(公告)日：2019-07-04

申请号：US15856075

申请日：2017-12-28

Applicant: Industrial Technology Research Institute ,  National Taiwan University Hospital

Inventor： Ching-Chuan Jiang ,  Fang-Jie Jang ,  Ming-Chia Yang ,  Yun-Han Lin

IPC: A61F2/30 ,  A61F2/46 ,  A61B17/16 ,  A61L27/56 ,  A61L27/58 ,  A61L27/18 ,  A61L27/16

Abstract: A cartilage repair implant, an auxiliary surgical tool kit and a cartilage repair system are provided. The cartilage repair implant includes a body and a plurality of pins. The body is a porous structure and is configured to carry cartilage repair material. The pins are fixed to the body for being inserted into a patient's bone. The auxiliary surgical tool kit includes a positioning sleeve and a click tool. The positioning sleeve has a through passage. A first alignment structure is disposed on the sidewall of the through passage. The click tool includes an outer tube and a push rod. A second alignment structure mutually aligned with the first alignment structure is disposed on the outer wall of the outer tube. The outer tube is configured to pass through the through passage. The push rod is slidably disposed in the outer tube. One end of the outer tube has a shaping blade for slicing a to-be-implanted region on an affected area of the patient. In which the shape of the to-be-implanted region is corresponding to the shape of the body.