公开(公告)号：US20200170838A1

公开(公告)日：2020-06-04

申请号：US16683277

申请日：2019-11-14

Applicant: Industrial Technology Research Institute

Inventor： Yun-Chung Teng ,  Yu-Bing Liou ,  Hsin-Yi Hsu ,  Ying-Wen Shen ,  Sen-Lu Chen ,  Yu-Chi Wang ,  Hsin-Hsin Shen

IPC: A61F9/00

Abstract: An eye wearing device is provided, including a body, at least one reservoir and at least one microchannel. The body has a first surface, a second surface, a center, a first outer edge of the first surface and a second outer edge of the second surface. The reservoir is disposed in the body to load the drug. The microchannel is disposed near the first outer edge of the first surface and the second outer edge of the second surface. One end of the microchannel is connected to the reservoir for filling the drug into the reservoir. The other end of the microchannel is an opening facing an edge of the eye wearing device for contacting the cornea and/or the sclera, and the opening is connected to the first outer edge of the first surface and the second outer edge of the second surface.

公开(公告)号：US11760853B2

公开(公告)日：2023-09-19

申请号：US17537728

申请日：2021-11-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Wei-Hong Chang ,  Ching-Mei Chen ,  Grace H. Chen ,  Hsin-Hsin Shen ,  Yuchi Wang ,  Ming-Chia Yang ,  Li-Hsin Lin ,  Sen-Lu Chen ,  Yi-Hsuan Lee ,  Jian-Wei Lin ,  Liang-Cheng Su

IPC: C08J5/18 ,  A61L24/04 ,  B32B27/36 ,  B32B9/02 ,  B32B9/04

CPC classification number: C08J5/18 ,  A61L24/043 ,  B32B9/02 ,  B32B9/045 ,  B32B27/36 ,  C08J2335/02 ,  A61L24/043 ,  C08L5/04 ,  A61L24/043 ,  C08L67/04 ,  A61L24/043 ,  C08L29/04 ,  A61L24/043 ,  C08L71/02

Abstract: An anti-curling film is provided. The anti-curling film includes a first portion and a second portion covering the first portion. The first portion includes polylactic acid (PLA), polycaprolactone (PCL), polyethylene glycol dimethacrylate (PEGDMA) and a photoinitiator. The second portion includes polycaprolactone (PCL), gelatin, hyaluronic acid (HA), alginate (AA), polyvinyl alcohol (PVA) or a combination thereof.

公开(公告)号：US11154637B2

公开(公告)日：2021-10-26

申请号：US16675860

申请日：2019-11-06

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Hsin-Hsin Shen ,  Yu-Chi Wang ,  Sen-Lu Chen ,  Yu-Bing Liou ,  Jian-Wei Lin ,  Yi-Hsuan Lee ,  Ming-Chia Yang ,  Ying-Wen Shen ,  Wei-Lin Yu

IPC: A61L24/06 ,  A61L24/00

Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.

公开(公告)号：US10449272B2

公开(公告)日：2019-10-22

申请号：US15294047

申请日：2016-10-14

Applicant: Industrial Technology Research Institute

Inventor： Yu-Chi Wang ,  Hsin-Hsin Shen ,  Chin-Fu Chen ,  Meng-Yow Hsieh ,  Sen-Lu Chen ,  Yu-Bing Liou ,  Tsai-Yu Lin ,  Pei-Shan Li ,  Wei-Lin Yu

IPC: A61L31/04 ,  A61L31/14

Abstract: The present disclosure provides a hydrogel composition including: a hydrogel having a structure represented by Formula (I) or Formula (II) shown as follows: A-B-BOX-B-A, Formula (I); B-A-B-(BOX-BAB)n-BOX-B-A-B, Formula (II), wherein, A is a hydrophilic polyethylene glycol polymer, B is a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2′-Bis(2-oxazoline) for coupling di-block of A-B or tri-block of B-A-B, and n is an integer greater than or equal to 0; and an anti-adhesion additive, wherein the anti-adhesion additive comprises a carbohydrate, a nitrogen-containing cyclic compound, a polymer or a combination thereof.