摘要:
This invention is a device and method for the detection of smooth surface lesions such as caries and tooth crown surface cracks on a tooth crown surface, the device having an ultrasonic surface wave transmitter/receiver (20) capable of transmitting ultrasonic surface waves along a tooth crown surface. Surface lesions encountered by the ultrasonic surface waves produce ultrasonic surface wave reflections which are receivable at the generator/receiver, thus enabling the presence of the lesion to be detected. The ultrasonic surface wave generator/receiver may comprise a transducer operatively connected to a wedge-like coupler (30). Longitudinal ultrasonic waves generated by the transducer are imparted onto the tooth surface by the coupler which has a contact surface in contact with the tooth surface being tested. The coupler also enables ultrasonic surface wave reflections to be received by the transducer.
摘要:
Provided are compositions including (3R, 4R, 6R)-stereoisomers of phenyl substituted pinenes having CB receptor agonist properties, methods of treating diseases or disorders with the pharmaceutical compositions, and processes for their preparation are also provided.
摘要:
The present invention relates to arylated camphenes, processes for their preparation and uses thereof for the manufacture of medicaments for the treatment of diseases, disorders or conditions associated with, or benefiting from stimulation of CB2 receptors.
摘要:
The present invention relates to arylated camphenes, processes for their preparation and uses thereof for the manufacture of medicaments for the treatment of diseases, disorders or conditions associated with, or benefiting from stimulation of CB2 receptors.
摘要:
Provided are compositions including (3R, 4R, 6R)-stereoisomers of phenyl substituted pinenes having CB receptor agonist properties, methods of treating diseases or disorders with the pharmaceutical compositions, and processes for their preparation are also provided.
摘要:
Novel methods and pharmaceutical compositions suitable for modulating bone growth and remodeling, preventing bone diseases, inducing bone growth or repair by cannabinoid receptor-mediated effects on bone cells is disclosed. Methods of identifying bone growth modulating agents are also disclosed.
摘要:
The present invention uncovers a highly significant association of SNPs in the CNR2 locus, encoding the cannabinoid receptor 2 protein, with osteoporosis. Methods and kits for determining predisposition to osteoporosis, improving diagnosis in individuals suspected of having osteoporosis are provided. Also provided a method of identifying a putative osteoporosis-causing genetic mutation in a subject.
摘要:
Novel methods and pharmaceutical compositions suitable for modulating bone growth and remodeling, preventing bone diseases, inducing bone growth or repair by cannabinoid receptor-mediated effects on bone cells is disclosed. Methods of identifying bone growth modulating agents are also disclosed.
摘要:
A device and method for the detection of smooth surface lesions such as caries and tooth crown surface cracks on a tooth crown surface, the device having an ultrasonic surface wave transmitter/receiver comprising a focused ultrasonic surface waves along a tooth crown surface. Surface lesions encountered by the ultrasonic surface waves produce ultrasonic surface wave reflections which are receivable at the generator/receiver, thus enabling the presence of the lesion, and particularly small lesions, to be detected. The ultrasonic surface wave generator/receiver may comprise a focused transducer, having a focusing element integral therewith or separate therefrom, operatively connected to a wedge-like coupler. Longitudinal ultrasonic waves generated by the transducers are at least partially focused by the focusing element and then imparted onto the tooth surface by the coupler which has a contact surface in contact with the tooth surface being tested. The coupler also enables ultrasonic surface wave reflections to be received by the transducer.
摘要:
An oral irrigator syringe bulb having an elastic compressible bulb, which may be filled with irrigation fluid, and a rigid nozzle having a base portion which may be sealingly fitted to the bulb. The nozzle has a lumen along the longitudinal axis thereof, and the lumen has a fluid outlet at its upper part to which suitable irrigation means can be attached. The nozzle also has an elongate non-kinking flexible dip tube which reaches into the lumen, the free end of the dip tube being provided with a weight, whereby when the nozzle is fitted onto the bulb the free end of the dip tube extends into the bulb and is submerged in the irrigation fluid at any spatial position in which the bulb is held.