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18 条记录 (耗时 0.023 秒)

    Distal or proximal fixation of over-the-tether myocardial leads
    13.
    发明申请
    Distal or proximal fixation of over-the-tether myocardial leads 有权
    远端或近端固定超过系绳心肌引线

    公开(公告)号：US20050137674A1

    公开(公告)日：2005-06-23

    申请号：US10972298

    申请日：2004-10-22

    申请人： M. Coe ,  Ronald Heil ,  Peter Kelley ,  Jason Shiroff ,  Randy Westlund ,  Donald Palme

    发明人： M. Coe ,  Ronald Heil ,  Peter Kelley ,  Jason Shiroff ,  Randy Westlund ,  Donald Palme

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0587 ,  A61N2001/0578

    摘要： The present invention is a myocardial lead attachment system for securing a lead within the myocardium. The attachment system includes an anchor configured to engage the heart, a tether coupled to the anchor and a lead body. The lead body has a proximal end, a distal end, a lumen for accepting the tether and a lock housing in the lumen. A lock structure is on the tether and mates with the lock housing and restrains motion of the lead with respect to the tether in either of a proximal or a distal direction.

    摘要翻译： 本发明是用于将铅固定在心肌内的心肌引导附着系统。 附接系统包括构造成接合心脏的锚，连接到锚固体的系绳和引导体。 引线体具有近端，远端，用于接纳系绳的内腔和在内腔中的锁定壳体。 锁定结构位于系绳上并且与锁定壳体配合并且在近端或远端方向中抑制引线相对于系绳的运动。

    Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
    15.
    发明授权
    Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth 有权
    具有生物相容性涂层的植入式传感器，用于控制或抑制组织生长

    公开(公告)号：US08696564B2

    公开(公告)日：2014-04-15

    申请号：US10888340

    申请日：2004-07-09

    申请人： Abhi Chavan ,  Jeffrey Ross ,  Cynthia Morrissey ,  Scott Mazar ,  Donald Palme

    发明人： Abhi Chavan ,  Jeffrey Ross ,  Cynthia Morrissey ,  Scott Mazar ,  Donald Palme

    IPC分类号： A61B5/04

    CPC分类号： B82Y30/00 ,  A61B5/00 ,  A61B5/0031 ,  B82Y15/00

    摘要： All or a portion of a surface of an implantable sensor is covered with a biocompatible coating formed at least partially of a biomaterial matrix having properties that promote a substantially even growth of tissue cells over the surface of the coating. Additional materials, such as growth factors, agents that recruit endogenous stem cells, and cell adhesion motif arginine, glycine, aspartic acid may be included in the coating. Autologous cells may be added to the coating prior to implantation. The sensor surface may also be textured, by etching or abrading, in order to promote even tissue growth. Alternatively, the sensor surface may be covered with a coating having properties that inhibit the growth of tissue. These coatings may include a biomaterial, a biomaterial matrix having a drug, such as a sirolimus or a steroid, an active component, or a self assembled monolayer.

    摘要翻译： 可植入传感器的表面的全部或一部分被至少部分地由具有促进组织细胞在涂层表面上的基本均匀生长的特性的生物材料基质形成的生物相容性涂层覆盖。 另外的材料，例如生长因子，招募内源性干细胞的药剂，细胞粘附基序精氨酸，甘氨酸，天冬氨酸可以包括在涂层中。 自体细胞可以在植入之前加入到涂层中。 为了促进均匀的组织生长，传感器表面也可以通过蚀刻或研磨进行纹理化。 或者，传感器表面可以被具有抑制组织生长的性质的涂层覆盖。 这些涂层可以包括生物材料，具有药物的生物材料基质，例如西罗莫司或类固醇，活性成分或自组装单层。

    Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
    16.
    发明申请
    Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth 有权
    具有生物相容性涂层的植入式传感器，用于控制或抑制组织生长

    公开(公告)号：US20060008500A1

    公开(公告)日：2006-01-12

    申请号：US10888340

    申请日：2004-07-09

    申请人： Abhi Chavan ,  Jeffrey Ross ,  Cynthia Morrissey ,  Scott Mazar ,  Donald Palme

    发明人： Abhi Chavan ,  Jeffrey Ross ,  Cynthia Morrissey ,  Scott Mazar ,  Donald Palme

    IPC分类号： A61N1/00 ,  A61F2/00

    CPC分类号： B82Y30/00 ,  A61B5/00 ,  A61B5/0031 ,  B82Y15/00

    摘要： All or a portion of a surface of an implantable sensor is covered with a biocompatible coating formed at least partially of a biomaterial matrix having properties that promote a substantially even growth of tissue cells over the surface of the coating. Additional materials, such as growth factors, agents that recruit endogenous stem cells, and cell adhesion motif arginine, glycine, aspartic acid may be included in the coating. Autologous cells may be added to the coating prior to implantation. The sensor surface may also be textured, by etching or abrading, in order to promote even tissue growth. Alternatively, the sensor surface may be covered with a coating having properties that inhibit the growth of tissue. These coatings may include a biomaterial, a biomaterial matrix having a drug, such as a sirolimus or a steroid, an active component, or a self assembled monolayer.

    摘要翻译： 可植入传感器的表面的全部或一部分被至少部分地由具有促进组织细胞在涂层表面上的基本均匀生长的特性的生物材料基质形成的生物相容性涂层覆盖。 另外的材料，例如生长因子，招募内源性干细胞的药剂，细胞粘附基序精氨酸，甘氨酸，天冬氨酸可以包括在涂层中。 自体细胞可以在植入之前加入到涂层中。 为了促进均匀的组织生长，传感器表面也可以通过蚀刻或研磨进行纹理化。 或者，传感器表面可以被具有抑制组织生长的性质的涂层覆盖。 这些涂层可以包括生物材料，具有药物的生物材料基质，例如西罗莫司或类固醇，活性成分或自组装单层。