公开(公告)号：US08440470B2

公开(公告)日：2013-05-14

申请号：US12970636

申请日：2010-12-16

Applicant: Jeffrey M. Raynor ,  Michaël Maurin ,  Mitchel O'Neal Perley ,  Pierre-Francois Lenne ,  Herve Rigneault ,  Renaud Vincentelli

Inventor： Jeffrey M. Raynor ,  Michaël Maurin ,  Mitchel O'Neal Perley ,  Pierre-Francois Lenne ,  Herve Rigneault ,  Renaud Vincentelli

IPC: G01N33/544

CPC classification number: G01N21/6454 ,  B01J19/0046 ,  B01J2219/00497 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00644 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00713 ,  B01J2219/00725 ,  C40B50/14 ,  Y10T156/10

Abstract: The disclosure relates to a fabrication process of a biosensor on a semiconductor wafer, comprising steps of: making a central photosensitive zone comprising at least one pixel-type biological analysis device comprising a photosensitive layer, and a first peripheral zone surrounding the central photosensitive zone, comprising electronic circuits. The first peripheral zone is covered by a hydrophilic coating, and the central photosensitive zone is covered with a hydrophobic coating. A barrier of a bio-compatible resin is formed on the second peripheral zone.

Abstract translation: 本公开涉及半导体晶片上的生物传感器的制造方法，包括以下步骤：制造包括至少一个像素型生物分析装置的中央感光区域，所述像素型生物分析装置包括感光层和围绕中央感光区域的第一周边区域， 包括电子电路。 第一周边区域由亲水涂层覆盖，中心感光区域被疏水涂层覆盖。 在第二周边区域上形成生物相容性树脂的屏障。

公开(公告)号：US08279306B2

公开(公告)日：2012-10-02

申请号：US11966001

申请日：2007-12-28

Applicant: Jeffrey M. Raynor

Inventor： Jeffrey M. Raynor

IPC: H04N5/235 ,  H04N3/14

CPC classification number: H04N5/357

Abstract: An imaging system includes a plurality of pixels. A pixel readout circuit produces a plurality of first image frames from those pixels. An image output circuit produces a plurality of second image frames and operates to produce a second image frame from more than one of the first image frames. The pixel readout circuit is enabled to produce the first images frames at a rate faster than the image output circuit produces the second image frames. Through combining first image frames, by averaging or other statistical combinations, the photon shot noise of second image frames is reduced. Photon shot noise affects images with high light levels more than those with low light levels and, as such, the system processing alters the rate of first image frames dependent on the current light levels.

Abstract translation: 成像系统包括多个像素。 像素读出电路从这些像素产生多个第一图像帧。 图像输出电路产生多个第二图像帧并且操作以从多于一个第一图像帧产生第二图像帧。 像素读出电路能够以比图像输出电路产生第二图像帧更快的速率产生第一图像帧。 通过组合第一图像帧，通过平均或其他统计组合，减少了第二图像帧的光子散射噪声。 光子散射噪声影响的光线水平高于低光级的图像，因此，系统处理会根据当前的光照水平改变第一图像帧的速率。

公开(公告)号：US08858885B2

公开(公告)日：2014-10-14

申请号：US12970615

申请日：2010-12-16

Applicant: Jeffrey M. Raynor ,  Michael Maurin ,  Mitchell O'Neal Perley ,  Pierre-Francois Lenne ,  Hervé Rigneault ,  Renaud Vincentelli

Inventor： Jeffrey M. Raynor ,  Michael Maurin ,  Mitchell O'Neal Perley ,  Pierre-Francois Lenne ,  Hervé Rigneault ,  Renaud Vincentelli

IPC: G01N21/01 ,  C40B50/14 ,  G01N21/64 ,  B01J19/00

CPC classification number: G01N21/6454 ,  B01J19/0046 ,  B01J2219/00497 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00644 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00713 ,  B01J2219/00725 ,  C40B50/14 ,  Y10T156/10

Abstract: The disclosure relates to a pixel-type biological analysis device comprising a photosensitive layer, a capture mixture for the capture of targeted proteins, the capture mixture being placed on an external surface of the photosensitive layer and comprising a protein probe grafted to a hydrogel, collection means for collecting photoelectrons in the photosensitive layer, and reading and treatment means of an electrical quantity supplied by the collection means, for the supply of a characteristic value of a luminous intensity detected by the photosensitive layer.

Abstract translation: 本公开涉及一种像素型生物分析装置，其包括感光层，用于捕获目标蛋白质的捕获混合物，捕获混合物置于感光层的外表面上并且包括接枝到水凝胶上的蛋白质探针 用于在感光层中收集光电子的装置以及由收集装置提供的电量的读取和处理装置，以提供由感光层检测的发光强度的特征值。

公开(公告)号：US08796936B2

公开(公告)日：2014-08-05

申请号：US12969095

申请日：2010-12-15

Applicant: Jeffrey M. Raynor

Inventor： Jeffrey M. Raynor

IPC: H05B37/02

CPC classification number: H01L31/02019 ,  H01J61/56 ,  H01J61/70 ,  H01L27/1446 ,  H01L31/02162 ,  H01L31/103 ,  H01L31/1032 ,  H01L31/145 ,  Y02B20/19

Abstract: An ambient light sensor integrated in a compact fluorescent lamp that, in turn, may include a controller and a radiation source. The ambient light sensor may include a radiation receiver to receive and filter incident radiation to obtain a value of the level of infrared radiation, and an electronic module to determine if the value is above a reference threshold value to enable the controller to switch the state of the radiation source.

Abstract translation: 集成在紧凑型荧光灯中的环境光传感器，其又可包括控制器和辐射源。 环境光传感器可以包括辐射接收器，用于接收和滤除入射辐射以获得红外辐射水平的值，以及电子模块，用于确定该值是否高于参考阈值，以使控制器能够切换 辐射源。