公开(公告)号：US06852986B1

公开(公告)日：2005-02-08

申请号：US10111114

申请日：2000-11-09

Applicant: Jerald D. Lee ,  Stanley D. Dabell

Inventor： Jerald D. Lee ,  Stanley D. Dabell

IPC: B01L7/00 ,  G01N21/25 ,  G01N21/64 ,  G01J1/58

CPC classification number: G01N21/6452 ,  B01L7/52 ,  B01L2300/0654 ,  B01L2300/1805 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2201/062 ,  Y10T436/143333

Abstract: This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present flourometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The flourometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each flourescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.

Abstract translation: 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的光学计具有低发热光源，例如发光二极管（LED），其与多个样品容器中的每一个具有一一对应关系，例如在标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。

公开(公告)号：US5404417A

公开(公告)日：1995-04-04

申请号：US80440

申请日：1993-06-21

Applicant: Melvin H. Johnson ,  Jerald D. Lee ,  Frank M. Willis

Inventor： Melvin H. Johnson ,  Jerald D. Lee ,  Frank M. Willis

IPC: G02B6/36 ,  G02B6/38 ,  G02B6/42

CPC classification number: G02B6/423 ,  G02B6/3803 ,  G02B6/3806 ,  G02B6/3838 ,  G02B6/4202 ,  G02B6/4204 ,  G02B6/3652 ,  G02B6/3692 ,  G02B6/3865

Abstract: A positioning apparatus for positioning a point on a cylindrical member having a small diameter, such as an optical fiber, along a predetermined reference axis regardless of the outer diameter of the fiber.

Abstract translation: 一种定位装置，用于沿着预定的参考轴线将光点定位在具有小直径的圆柱形构件（例如光纤）上，而不管光纤的外径如何。

公开(公告)号：US5133030A

公开(公告)日：1992-07-21

申请号：US735661

申请日：1991-07-26

Applicant: Jerald D. Lee

Inventor： Jerald D. Lee

IPC: G02B6/26 ,  G02B6/28 ,  G02B6/35 ,  G02B26/08

CPC classification number: G02B6/3512 ,  G02B6/2817 ,  G02B6/352 ,  G02B6/353 ,  G02B6/3552 ,  G02B6/3588

Abstract: A switch for controlling the transmission of light from a first optical fiber to at least a second optical fiber or from a single bidirectional optical fiber back to itself includes a housing having a spherical concave reflector mounted therewithin. Fiber mounting means is provided for mounting optical fiber(s) at a predetermined location within the housing such that at least a portion of a beam of light emanating from the end face of one fiber propagates along an incidence path toward the reflector from which it is reflected by the curved concave reflector along a predetermined reflectance path. A light interrupter is mounted within the housing for switchable movement between a light transmissive state and a light interruptive state. A light absorbing member is positioned such that residual light reflected from the light interrupter is directed toward and absorbed by the light absorbing member. A switch presence indicator for providing an indication that the light interrupter is disposed in the interdiction position may also be included.

Abstract translation: 用于控制从第一光纤到至少第二光纤或从单个双向光纤返回到自身的光的传输的开关包括其中安装有球面凹面反射器的壳体。 提供光纤安装装置，用于将光纤安装在壳体内的预定位置处，使得从一个光纤的端面发出的光束的至少一部分沿入射路径朝向反射器传播， 由弯曲的凹面反射体沿着预定的反射路径反射。 一个光断续器安装在壳体内，用于在透光状态和光中断状态之间进行切换运动。 光吸收构件被定位成使得从遮光器反射的残留光被引导并被光吸收构件吸收。 还可以包括用于提供光断续器置于停止位置的指示的开关存在指示器。

公开(公告)号：US4698649A

公开(公告)日：1987-10-06

申请号：US804136

申请日：1985-12-03

Applicant: Jerald D. Lee

Inventor： Jerald D. Lee

IPC: B41J2/44 ,  B41J11/42 ,  B41J19/76 ,  G01S17/58 ,  H02P23/00 ,  G01D9/42

CPC classification number: B41J11/425 ,  G01S17/58 ,  H02P23/16

Abstract: A control system for controlling the velocity of a member in a printing system which utilizes a signal representative of the time variation in intensity produced by the Doppler shift between radiation reflected from the moving member and a reference signal to generate a control signal for correcting the velocity of the moving member. The control signal is applied to a servo mechanism to modify the velocity of the moving member in the appropriate manner.

Abstract translation: 一种用于控制打印系统中的部件的速度的控制系统，其利用表示由从移动部件反射的辐射之间的多普勒频移产生的强度的时间变化的信号和参考信号，以产生用于校正速度的控制信号 的移动构件。 控制信号被施加到伺服机构，以适当的方式改变移动部件的速度。

公开(公告)号：US4412744A

公开(公告)日：1983-11-01

申请号：US268707

申请日：1981-06-01

Applicant: Jerald D. Lee ,  Charles D. Reilly

Inventor： Jerald D. Lee ,  Charles D. Reilly

IPC: G01J3/42 ,  G01N21/27

CPC classification number: G01J3/42

Abstract: An improved spectrophotometer having a light source, a scanning type monochromator that provides light beams of different wavelengths over a light spectrum being scanned, and an object photometer for measuring the intensity of reflected light from an object being tested and generating an electrical signal proportional to the intensity of the light measured and connected to means for recording the signal as a function of wavelength measured, the improvement used therewith comprising:(a) a beam splitter that divides the beam exiting from the monochromator into first and second light beams, whereby the first beam is incident upon the object;(b) a reference photometer that measures the flux of the second light beam and generates an output electrical signal proportional to the intensity of the light measured; and(c) a light source control, connecting the reference photometer and the light source, which receives the electrical signal from the reference photometer and generates a feedback electrical signal to adjust the intensity of the light source to maintain the reference photometer output electrical signal level constant across the light spectrum that is being scanned.The spectrophotometer is useful for determining standard color values for coatings on substrates or for any colored surface.

Abstract translation: 一种具有光源的改进的分光光度计，在被扫描的光谱上提供不同波长的光束的扫描型单色仪，以及用于测量被测物体的反射光强度的物体光度计，并产生与 所测量的光的强度与用于记录所测量的波长的函数的信号连接，所用的改进包括：（a）分束器，其将从单色仪离开的光束分成第一和第二光束， 光束入射到物体上; （b）参考光度计，其测量第二光束的通量并产生与所测量的光的强度成比例的输出电信号; 和（c）光源控制器，连接参考光度计和光源，其接收来自参考光度计的电信号，并产生反馈电信号以调节光源的强度以保持参考光度计输出电信号电平 恒定在被扫描的光谱上。 分光光度计可用于确定基材或任何有色表面上涂层的标准颜色值。

公开(公告)号：US20120183968A1

公开(公告)日：2012-07-19

申请号：US13351885

申请日：2012-01-17

Applicant: Jerald D. Lee ,  Stanley D. Dabell

Inventor： Jerald D. Lee ,  Stanley D. Dabell

IPC: G01N21/64 ,  C12M1/40

CPC classification number: G01N21/6452 ,  B01L7/52 ,  B01L2300/0654 ,  B01L2300/1805 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2201/062 ,  Y10T436/143333

Abstract: This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its to correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.

Abstract translation: 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED与其对应定位的容器之间的光路，以及在定位的容器内的每个荧光样品与光信号感测装置之间的另一光路。 仪器可以由电脑控制。

公开(公告)号：US20080212090A1

公开(公告)日：2008-09-04

申请号：US12052212

申请日：2008-03-20

Applicant: Jerald D. Lee ,  Stanley D. Dabell

Inventor： Jerald D. Lee ,  Stanley D. Dabell

IPC: G01J3/30

CPC classification number: G01N21/6452 ,  B01L7/52 ,  B01L2300/0654 ,  B01L2300/1805 ,  G01N21/6428 ,  G01N21/6456 ,  G01N2201/062 ,  Y10T436/143333

Abstract: This invention concerns a fluorometer preferably combined with a thermal cycler useful in biochemical protocols such as polymerase chain reaction (PCR) and DNA melting curve analysis. The present fluorometer features a low heat-generating light source such as a light emitting diode (LED), having a one-to-one correspondence to each of a plurality of sample containers, such as capped PCR tubes in a standard titer tray. The fluorometer of the present invention further comprises an optical path between each LED and its correspondingly positioned container, and another optical path between each fluorescing sample within the positioned container and an optical signal sensing means. The instrument can be computer controlled.

Abstract translation: 本发明涉及一种荧光计，优选与可用于生物化学方案如PCR聚合酶链反应（PCR）和DNA熔解曲线分析的热循环仪组合。 本发明的荧光计具有诸如发光二极管（LED）的低发热光源，其与多个样品容器中的每一个具有一一对应关系，例如标准滴定盘中的封盖PCR管。 本发明的荧光计还包括在每个LED和其相应定位的容器之间的光路，以及在定位的容器内的每个荧光样品和光信号感测装置之间的另一光路。 仪器可以由电脑控制。

公开(公告)号：US5175776A

公开(公告)日：1992-12-29

申请号：US773734

申请日：1991-10-08

Applicant: Jerald D. Lee

Inventor： Jerald D. Lee

IPC: G02B6/35 ,  G02B6/38

CPC classification number: G02B6/3839 ,  G02B6/3502 ,  G02B6/3546 ,  G02B6/3582

Abstract: An optical fiber switch in which the switching force is applied directly to the fiber. A biasing force, generated by a bending of the fiber, is exerted on the fiber in a direction tending to urge the same toward the bottom of a first groove. The switching force is applied transversely to the direction of the biasing force, and moves the fiber out of the first groove and into a second, adjacent groove. When in the second groove, the biasing force on the fiber urges the same toward the bottom of the second groove.

Abstract translation: 一种光纤开关，其中切换力直接施加到光纤上。 通过纤维的弯曲产生的偏压力沿着倾向于将其推向第一凹槽的底部的方向施加在纤维上。 切换力横向于偏压力的方向施加，并且将光纤从第一槽移出并进入第二相邻的槽。 当在第二凹槽中时，纤维上的偏置力朝向第二凹槽的底部推压。

公开(公告)号：US4911520A

公开(公告)日：1990-03-27

申请号：US262935

申请日：1988-10-20

Applicant: Jerald D. Lee

Inventor： Jerald D. Lee

IPC: G02B26/08 ,  G02B6/35

CPC classification number: G02B6/3508 ,  G02B6/3552 ,  G02B6/3566 ,  G02B6/3582 ,  Y10T29/49105 ,  Y10T29/49114

Abstract: A fiber optic switch has a fixed member and a movable member mounted for cantilevered movement with respect thereto. Both of the members are fabricated from borosilicate glass.

Abstract translation: 光纤开关具有固定部件和安装成相对于其悬臂运动的可动部件。 两个构件均由硼硅酸盐玻璃制成。

公开(公告)号：US4282431A

公开(公告)日：1981-08-04

申请号：US86044

申请日：1979-10-18

Applicant: John D. Anthony, Jr. ,  John J. Keegan, Jr. ,  Jerald D. Lee

Inventor： John D. Anthony, Jr. ,  John J. Keegan, Jr. ,  Jerald D. Lee

IPC: G06K7/10 ,  G06K9/20 ,  H01J3/14

CPC classification number: G06K7/10871 ,  G06K2207/1016

Abstract: A circular scan reader utilizes oscillating mirrors and associated optics to generate a circular scan pattern of laser light focused to a small spot. The angle of the scan emanating from a point just inside the reader through a window forms a conical shape which permits scanning inside a yarn tube without inserting any portion of the reader into the tube. When the scan passes over a bar coded label, the changes in reflection of light between the bars and spaces are detected by a photodetector mounted on the face of the window. These fluctuations in light which correspond in width to the bar and space width are converted to an electrical signal that is amplified, and decoded. A driver circuit for the oscillating mirrors controls the scan rate and scan pattern. The scan rate is modulated to cause a variation in the sweep depth in the tube thus providing an area scan. The area scan reduces the need for accurate label placement in the tube core.

Abstract translation: 圆形扫描读取器利用振荡镜和相关光学器件产生聚焦到小点的激光的圆形扫描图案。 通过窗口从阅读器内部的点发出的扫描角度形成圆锥形状，其允许在纱管内扫描而不将读取器的任何部分插入管中。 当扫描通过条形编码标签时，通过安装在窗口的表面上的光电检测器检测条和空间之间的光的反射变化。 在宽度对应于条和空间宽度的光中的这些波动被转换成被放大和解码的电信号。 用于振荡镜的驱动电路控制扫描速率和扫描模式。 扫描速率被调制以引起管中的扫描深度的变化，从而提供区域扫描。 区域扫描减少了在管芯中准确标签放置的需要。