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11.发明申请公开(公告)号：US20090018618A1
公开(公告)日：2009-01-15
申请号：US11776170
申请日：2007-07-11
申请人： Jordi Parramon , Jess W. Shi
发明人： Jordi Parramon , Jess W. Shi
IPC分类号： A61N1/02
CPC分类号： A61N1/37252 , A61N1/3605 , A61N1/37205 , Y10S128/903
摘要： An improved arbitration scheme for allowing concurrent stimulation and telemetry listening in a microstimulator is disclosed. A listening window for telemetry is permitted to proceed, and access to the microstimulator's coil granted, during at least a portion of the inter-pulse period that follows the issuance of a stimulation pulse. This is permissible because access to the coil is not needed during the entirety of the inter-pulse period. For example, the listening window can issue during that portion of the inter-pulse period when the decoupling capacitor is discharged, but cannot issue during that portion of the inter-pulse period when the compliance voltage is being generated for the next stimulation pulse. However, because compliance voltage generation occupies only a small portion of the inter-pulse period, the technique is not substantially limited. By allowing the listening window to issue during the majority of the inter-pulse period, the listening window produces smaller gaps between the pulses, and stimulation therapy is thus brought closer to its ideal.
摘要翻译： 公开了一种用于允许微型激励器中的并发刺激和遥测监听的改进的仲裁方案。 在发出刺激脉冲之后的脉冲间期间的至少一部分期间，允许遥测监听窗口继续进行微型刺激器线圈的访问。 这是允许的，因为在整个脉冲间期间不需要对线圈的访问。 例如，当解耦电容器放电时，在脉冲周期的该部分期间可以发出监听窗口，但是当为下一个刺激脉冲产生顺从性电压时，不能在脉冲间期间的那部分期间发出监听窗口。 然而，由于顺应性电压产生仅占脉冲周期的一小部分，所以该技术基本上不受限制。 通过允许在大多数脉冲间期间发出听音窗口，收听窗口在脉冲之间产生较小的间隙，因此刺激疗法更接近其理想。
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12.发明授权Multi-electrode implantable stimulator device with a single current path decoupling capacitor 有权具有单电流路径去耦电容器的多电极可植入刺激装置公开(公告)号：US07881803B2
公开(公告)日：2011-02-01
申请号：US11550655
申请日：2006-10-18
申请人： Jordi Parramon , Kiran Nimmagadda , Emanuel Feldman , Yuping He
发明人： Jordi Parramon , Kiran Nimmagadda , Emanuel Feldman , Yuping He
IPC分类号： A61N1/40
CPC分类号： A61N1/36125 , A61N1/025 , A61N1/08 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Disclosed herein are circuits and methods for a multi-electrode implantable stimulator device incorporating one decoupling capacitor in the current path established via at least one cathode electrode and at least one anode electrode. In one embodiment, the decoupling capacitor may be hard-wired to a dedicated anode on the device. The cathodes are selectively activatable via stimulation switches. In another embodiment, any of the electrodes on the devices can be selectively activatable as an anode or cathode. In this embodiment, the decoupling capacitor is placed into the current path via selectable anode and cathode stimulation switches. Regardless of the implementation, the techniques allow for the benefits of capacitive decoupling without the need to associate decoupling capacitors with every electrode on the multi-electrode device, which saves space in the body of the device. Although of particular benefit when applied to microstimulators, the disclosed technique can be used with space-saving benefits in any stimulator device.
摘要翻译： 本文公开了用于在经由至少一个阴极电极和至少一个阳极电极建立的电流路径中并入一个去耦电容器的多电极可植入刺激器装置的电路和方法。 在一个实施例中，去耦电容器可以硬连接到器件上的专用阳极。 阴极可以通过刺激开关选择性地激活。 在另一个实施例中，器件上的任何电极可以选择性地激活为阳极或阴极。 在该实施例中，去耦电容通过可选择的阳极和阴极刺激开关放置在电流路径中。 不管实施方案如何，这些技术允许电容去耦的优点，而不需要将去耦电容器与多电极器件上的每个电极相关联，这节省了器件体内的空间。 虽然在应用于微型激励器时特别有益，但是所公开的技术可以在任何刺激器装置中具有节省空间的优点。
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13.发明授权Method and device for acquiring physiological data during tissue stimulation procedure 有权在组织刺激过程中获取生理数据的方法和装置公开(公告)号：US09399132B2
公开(公告)日：2016-07-26
申请号：US12825187
申请日：2010-06-28
CPC分类号： A61N1/08 , A61B5/04001 , A61B5/053 , A61B5/0538 , A61N1/0551 , A61N1/36071 , A61N1/36135 , A61N1/36164 , A61N1/37235
摘要： A method and system of providing therapy to a patient implanted with an array of electrodes is provided. A train of electrical stimulation pulses is conveyed within a stimulation timing channel between a group of the electrodes to stimulate neural tissue, thereby providing continuous therapy to the patient. Electrical parameter is sensed within a sensing timing channel using at least one of the electrodes, wherein the first stimulation timing channel and sensing timing channel are coordinated, such that the electrical parameter is sensed during the conveyance of the pulse train within time slots that do not temporally overlap any active phase of the stimulation pulses.
摘要翻译： 提供了向植入电极阵列的患者提供治疗的方法和系统。 一组电刺激脉冲在一组电极之间的刺激定时通道内传送以刺激神经组织，从而为患者提供持续的治疗。 使用至少一个电极在感测定时通道内感测电参数，其中协调第一激励定时通道和感测定时通道，使得在脉冲串的传送期间在不在的时隙内感测电参数 在时间上重叠刺激脉冲的任何活动相位。
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14.发明授权公开(公告)号：US08577474B2
公开(公告)日：2013-11-05
申请号：US12616178
申请日：2009-11-11
CPC分类号： A61N1/37217 , A61N1/3718 , A61N1/37211 , A61N1/37229 , A61N1/3758 , A61N1/3787
摘要： An improved implantable pulse generator (IPG) containing improved telemetry circuitry is disclosed. The IPG includes charging and telemetry coils within the IPG case, which increases their mutual inductance and potential to interfere with each other; particularly problematic is interference to the telemetry coil caused by the charging coil. To combat this, improved telemetry circuitry includes decoupling circuitry for decoupling the charging coil during periods of telemetry between the IPG and an external controller. Such decoupling circuitry can comprise use of pre-existing LSK circuitry during telemetry, or new discrete circuitry dedicated to decoupling. The decoupling circuitry is designed to prevent or at least reduce induced current flowing through the charging coil during data telemetry. The decoupling circuitry can be controlled by the microcontroller in the IPG, or can automatically decouple the charging coil at appropriate times to mitigate an induced current without instruction from the microcontroller.
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15.发明授权Ultracapacitor powered implantable pulse generator with dedicated power supply 有权具有专用电源的超级电容器动力植入脉冲发生器公开(公告)号：US08175717B2
公开(公告)日：2012-05-08
申请号：US11221095
申请日：2005-09-06
IPC分类号： A61N1/00
CPC分类号： A61N1/3787 , A61N1/37247 , A61N1/37258 , A61N1/37264
摘要： A stimulator includes an implantable pulse generator comprising circuit elements, a first power source, such as an ultracapacitor, that provides operating power for the circuit elements of the pulse generator. The pulse generator can also have a memory associated therewith, such as a volatile memory for storing programming data. A second power source that has higher voltage retention than the first power source can also be included. The second power source can be dedicated to the volatile memory and can provide operating power for the volatile memory.
摘要翻译： 刺激器包括可植入脉冲发生器，其包括电路元件，第一电源，例如超级电容器，其为脉冲发生器的电路元件提供工作电力。 脉冲发生器还可以具有与其相关联的存储器，诸如用于存储编程数据的易失性存储器。 还可以包括比第一电源具有更高的电压保持的第二电源。 第二个电源可以专用于易失性存储器，并且可以为易失性存储器提供工作电源。
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16.发明申请METHOD AND DEVICE FOR ACQUIRING PHYSIOLOGICAL DATA DURING TISSUE STIMULATION PROCEDURE 有权在组织刺激过程中获取生理数据的方法和装置公开(公告)号：US20100331916A1
公开(公告)日：2010-12-30
申请号：US12825187
申请日：2010-06-28
CPC分类号： A61N1/08 , A61B5/04001 , A61B5/053 , A61B5/0538 , A61N1/0551 , A61N1/36071 , A61N1/36135 , A61N1/36164 , A61N1/37235
摘要： A method and system of providing therapy to a patient implanted with an array of electrodes is provided. A train of electrical stimulation pulses is conveyed within a stimulation timing channel between a group of the electrodes to stimulate neural tissue, thereby providing continuous therapy to the patient. Electrical parameter is sensed within a sensing timing channel using at least one of the electrodes, wherein the first stimulation timing channel and sensing timing channel are coordinated, such that the electrical parameter is sensed during the conveyance of the pulse train within time slots that do not temporally overlap any active phase of the stimulation pulses.
摘要翻译： 提供了向植入电极阵列的患者提供治疗的方法和系统。 一组电刺激脉冲在一组电极之间的刺激定时通道内传送以刺激神经组织，从而为患者提供持续的治疗。 使用至少一个电极在感测定时通道内感测电参数，其中协调第一激励定时通道和感测定时通道，使得在脉冲串的传送期间在不在的时隙内感测电参数 在时间上重叠刺激脉冲的任何活动相位。
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17.发明申请Multi-Electrode Implantable Stimulator Device with a Single Current Path Decoupling Capacitor 有权具有单电流路径去耦电容器的多电极植入式刺激器装置公开(公告)号：US20080097529A1
公开(公告)日：2008-04-24
申请号：US11550655
申请日：2006-10-18
申请人： Jordi Parramon , Kiran Nimmagadda , Emanuel Feldman , Yuping He
发明人： Jordi Parramon , Kiran Nimmagadda , Emanuel Feldman , Yuping He
IPC分类号： A61N1/00
CPC分类号： A61N1/36125 , A61N1/025 , A61N1/08 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Disclosed herein are circuits and methods for a multi-electrode implantable stimulator device incorporating one decoupling capacitor in the current path established via at least one cathode electrode and at least one anode electrode. In one embodiment, the decoupling capacitor may be hard-wired to a dedicated anode on the device. The cathodes are selectively activatable via stimulation switches. In another embodiment, any of the electrodes on the devices can be selectively activatable as an anode or cathode. In this embodiment, the decoupling capacitor is placed into the current path via selectable anode and cathode stimulation switches. Regardless of the implementation, the techniques allow for the benefits of capacitive decoupling without the need to associate decoupling capacitors with every electrode on the multi-electrode device, which saves space in the body of the device. Although of particular benefit when applied to microstimulators, the disclosed technique can be used with space-saving benefits in any stimulator device.
摘要翻译： 本文公开了用于在经由至少一个阴极电极和至少一个阳极电极建立的电流路径中并入一个去耦电容器的多电极可植入刺激器装置的电路和方法。 在一个实施例中，去耦电容器可以硬连接到器件上的专用阳极。 阴极可以通过刺激开关选择性地激活。 在另一个实施例中，器件上的任何电极可以选择性地激活为阳极或阴极。 在该实施例中，去耦电容通过可选择的阳极和阴极刺激开关放置在电流路径中。 不管实施方案如何，这些技术允许电容去耦的优点，而不需要将去耦电容器与多电极器件上的每个电极相关联，这节省了器件体内的空间。 虽然在应用于微型激励器时特别有益，但是所公开的技术可以在任何刺激器装置中具有节省空间的优点。
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公开(公告)号：US09393433B2
公开(公告)日：2016-07-19
申请号：US13489770
申请日：2012-06-06
发明人： Jordi Parramon , Goran N. Marnfeldt , Robert Ozawa , Emanuel Feldman , Dave Peterson , Yuping He
CPC分类号： A61N1/3787 , A61N1/08
摘要： Battery management circuitry for an implantable medical device such as an implantable neurostimulator is described. The circuitry has a T-shape with respect to the battery terminal, with charging circuitry coupled between rectifier circuitry and the battery terminal on one side of the T, and load isolation circuitry coupled between the load and the battery terminal on the other side. The load isolation circuitry can comprise two switches wired in parallel. An undervoltage fault condition opens both switches to isolate the battery terminal from the load to prevent further dissipation of the battery. Other fault conditions will open only one the switches leaving the other closed to allow for reduced power to the load to continue implant operations albeit at safer low-power levels. The battery management circuitry can be fixed in a particular location on an integrated circuit which also includes for example the stimulation circuitry for the electrodes.
摘要翻译： 描述了诸如可植入神经刺激器的可植入医疗装置的电池管理电路。 电路相对于电池端子具有T形，充电电路耦合在整流器电路和T的一侧上的电池端子之间，负载隔离电路耦合在另一侧的负载和电池端子之间。 负载隔离电路可以包括并联的两个开关。 欠压故障条件打开两个开关以将电池端子与负载隔离，以防止电池进一步耗散。 其他故障条件将仅打开一个开关，使另一个闭合，以允许降低负载的功率，以继续进行种植体操作，尽管处于更安全的低功率水平。 电池管理电路可以固定在集成电路的特定位置，该集成电路还包括例如用于电极的刺激电路。
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19.发明授权Communication and charging circuitry for a single-coil implantable medical device 有权用于单线圈可植入医疗设备的通信和充电电路公开(公告)号：US08666504B2
公开(公告)日：2014-03-04
申请号：US13608490
申请日：2012-09-10
IPC分类号： A61N1/05
CPC分类号： H01F38/14 , A61N1/36 , A61N1/37223 , A61N1/3787 , H02J50/12 , H04Q9/12
摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.
摘要翻译： 描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。 该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。 因此，容器电路被简化并且不包含可切换的部件。 开关串联连接到电路直流侧的存储电容器。 在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。 在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。
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20.发明申请Communication and Charging Circuitry for a Single-Coil Implantable Medical Device 有权单线圈可植入医疗设备的通信和充电电路公开(公告)号：US20130103115A1
公开(公告)日：2013-04-25
申请号：US13608490
申请日：2012-09-10
IPC分类号： A61N1/08
CPC分类号： H01F38/14 , A61N1/36 , A61N1/37223 , A61N1/3787 , H02J50/12 , H04Q9/12
摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.
摘要翻译： 描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。 该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。 因此，容器电路被简化并且不包含可切换的部件。 开关串联连接到电路直流侧的存储电容器。 在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。 在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。
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