公开(公告)号：US09040488B2

公开(公告)日：2015-05-26

申请号：US13061734

申请日：2009-09-02

申请人： Timothy M. Block ,  Jinhong Chang ,  Xiaodong Xu

发明人： Timothy M. Block ,  Jinhong Chang ,  Xiaodong Xu

IPC分类号： C07D211/46 ,  A61K31/445 ,  A61K31/47 ,  A61K31/7056

CPC分类号： A61K31/47 ,  A61K31/7056 ,  C07D211/46 ,  Y02A50/393 ,  A61K2300/00

摘要： Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit broad spectrum antiviral activities against many enveloped viruses. Previously we have reported a novel DNJ derivative, OSL-95II, with antiviral activity and reduced cytotoxicity. In order to develop imino sugars with more potent antiviral activity as well as improved toxicity profile, OSL-95II was modified by diversifying the nitrogen linked alkylated side chain. The antiviral activities were initially tested in bovine viral diarrhea virus (BVDV) infected MDBK cells, yielding several imino sugar derivatives with novel structure and superior antiviral activity and toxicity profile. Furthermore, these new compounds were shown to be active against Dengue virus (DV) and West Nile virus (WNV) infection in BHK cells where potent anti-DV activity having submicromolar EC50 values and SI of greater than 900. These compounds represent a new generation of iminio sugars and their analogues, having application in the clinical treatment of infection of DV and other members of flaviviridae.

摘要翻译： 诸如脱氧野尻霉素（DNJ）的亚氨基糖是选择性抑制细胞α-葡萄糖苷酶I和II（在糖蛋白中加工N-连接聚糖的酶）并且对许多包膜病毒展现广谱抗病毒活性的葡萄糖类似物。 以前我们已经报道了具有抗病毒活性和降低的细胞毒性的新型DNJ衍生物OSL-95II。 为了开发具有更强的抗病毒活性和改善的毒性特征的亚氨基糖，OSL-95II通过使氮连接的烷基化侧链多样化而被修饰。 首先在牛病毒性腹泻病毒（BVDV）感染的MDBK细胞中测试抗病毒活性，产生几种具有新结构和优良抗病毒活性和毒性特征的亚氨基糖衍生物。 此外，这些新化合物被证明对BHK细胞中登革热病毒（DV）和西尼罗病毒（WNV）感染具有活性，其中具有亚微摩尔EC 50值和SI大于900的有效抗DV活性。这些化合物代表新一代 的亚氨基糖及其类似物，可用于临床治疗DV和其他黄病毒成分的感染。

公开(公告)号：US08807618B2

公开(公告)日：2014-08-19

申请号：US13580035

申请日：2011-02-14

申请人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

发明人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

IPC分类号： B60R11/02

CPC分类号： B60R11/02 ,  B60K2350/00 ,  B60K2350/941 ,  B60K2350/945 ,  B60K2350/946 ,  B60K2350/948 ,  B60R2011/0047

摘要： A connecting device adapted for connecting a multifunctional box with a vehicle multimedia system may be provided. The connecting device may comprise a shell for holding the multifunctional box having a first open end portion and a second end portion configured with an interface, via which the multifunctional box is electrically connected with the vehicle multimedia system in a releasable manner; a locking unit formed on at least a lateral side between the first open portion and the second end portion for releasably locking the multifunctional box; and a release unit formed on the shell to release the inserted multifunctional box when pressed. A vehicle comprising the connecting device may also be provided.

摘要翻译： 可以提供适于将多功能盒与车载机多媒体系统连接的连接装置。 连接装置可以包括用于保持具有第一开口端部的多功能盒和配置有接口的第二端部的壳体，多功能盒通过该接口以可释放的方式与车辆多媒体系统电连接; 形成在所述第一开口部和所述第二端部之间的至少一侧的锁定单元，用于可释放地锁定所述多功能盒; 以及形成在外壳上的释放单元，以在按压时释放插入的多功能盒。 还可以提供包括连接装置的车辆。

公开(公告)号：US20130308571A1

公开(公告)日：2013-11-21

申请号：US13896454

申请日：2013-05-17

申请人： Xiaofeng Tao ,  Ping Zhang ,  Xiaona Li ,  Qimei Cui ,  Xiaodong Xu ,  Yingyue Xu ,  Waheed ur Rehman

发明人： Xiaofeng Tao ,  Ping Zhang ,  Xiaona Li ,  Qimei Cui ,  Xiaodong Xu ,  Yingyue Xu ,  Waheed ur Rehman

IPC分类号： H04W16/02

CPC分类号： H04W16/02 ,  H04W16/12 ,  H04W16/30

摘要： The present invention relates to the technical field of wireless communication, and discloses a method for frequency reuse based on cellular network. The method comprises the following steps: dividing the whole cellular network into a plurality of different cell clusters, wherein each cell cluster comprises three cells, every two of them being adjacent to each other; for each cell in a cell cluster, dividing the cell into a central area and an edge area according to the coverage of the cell; dividing the whole available frequency band of the network according to the user distribution and service distribution in the cell cluster; allocating divided frequency bands to the central area and the edge area in the cell cluster respectively according to preset rule; and applying the method for frequency reuse to other cell clusters, thus achieving the frequency reuse of the whole network. With the method, the average spectrum frequency efficiency of the cellular network can be improved, and interference among cells can be effectively suppressed.

摘要翻译： 本发明涉及无线通信的技术领域，并且公开了一种基于蜂窝网络的频率复用方法。 该方法包括以下步骤：将整个蜂窝网络划分成多个不同的小区簇，其中每个小区簇包括三个小区，每个小区彼此相邻; 对于小区簇中的每个小区，根据小区的覆盖范围将小区划分成中心区域和边缘区域; 根据用户分布和服务分布对网络的整个可用频带进行划分; 根据预设规则分别将细分簇的频带分配给小区簇中的中心区域和边缘区域; 并将频率重用方法应用于其他小区集群，从而实现整个网络的频率重用。 利用该方法，可以提高蜂窝网络的平均频谱频率效率，并且可以有效地抑制小区之间的干扰。

公开(公告)号：US20130303552A1

公开(公告)日：2013-11-14

申请号：US13877870

申请日：2011-10-04

申请人： Xiaodong Xu ,  Andrea Cuconati ,  Timothy M. Block ,  Tong Xiao

发明人： Xiaodong Xu ,  Andrea Cuconati ,  Timothy M. Block ,  Tong Xiao

IPC分类号： A61K31/519 ,  C07D487/04 ,  A61K45/06

CPC分类号： C07D487/04 ,  A61K31/519 ,  A61K45/06 ,  A61K2300/00

摘要： Pharmaceutical compositions of the invention comprise triazolopyrimidines useful for the treatment of hepatitis virus in a patient.

公开(公告)号：US08824426B2

公开(公告)日：2014-09-02

申请号：US13501549

申请日：2010-10-12

申请人： Jun Wang ,  Xiaodong Xu

发明人： Jun Wang ,  Xiaodong Xu

IPC分类号： H04J3/00 ,  H04L5/00 ,  H04W48/08 ,  H04W72/04 ,  H04W24/00

CPC分类号： H04W48/08 ,  H04L5/0007 ,  H04L5/001 ,  H04L5/0053 ,  H04W24/00 ,  H04W72/042

摘要： A method for transmitting Physical Downlink Control Channel (PDCCH) information, a method for determining PDCCH search space and devices thereof are disclosed in the present embodiments. The method for determining PDCCH search space includes the following step: Node B (NB) determines the different search spaces corresponding to different PDCCHs according to Carrier Indicator (CI) information. By applying the technical solution provided in the embodiments of the present invention, the CI information is introduced in the search space determining process, so that different search spaces can be allocated to the cross-carrier PDCCHs of one User Equipment (UE) and the NB and UE are able to exactly determine the search spaces of PDCCHs in each downlink carrier, therefore reducing the blocking probability during PDCCH scheduling process and improving the reliability of PDCCH transmission.

摘要翻译： 在本实施例中公开了用于发送物理下行链路控制信道（PDCCH）信息的方法，用于确定PDCCH搜索空间的方法及其装置。 确定PDCCH搜索空间的方法包括以下步骤：节点B（NB）根据载波指示符（CI）信息确定与不同PDCCH相对应的不同搜索空间。 通过应用本发明实施例提供的技术方案，在搜索空间确定过程中引入了CI信息，从而可以将不同的搜索空间分配给一个用户设备（UE）和NB的跨载波PDCCH UE能够精确地确定每个下行链路载波中的PDCCH的搜索空间，因此降低了PDCCH调度过程中的阻塞概率，提高了PDCCH传输的可靠性。

公开(公告)号：US20130223272A1

公开(公告)日：2013-08-29

申请号：US13884368

申请日：2011-10-27

申请人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

发明人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

IPC分类号： H04W24/10

CPC分类号： H04W24/10 ,  H04B7/024 ,  H04B7/0626 ,  H04W72/0426 ,  H04W92/20

摘要： Disclosed is a method for establishing a CoMP cooperating set in coordinated multi-point communication, the method comprising the steps of: triggering and starting a coordinated multi-point communication process; according to channel state information of all cells in a measurement cell set measured by a UE, determining a candidate CoMP cooperating set; sending a CoMP cooperating set establishment request to eNodeBs of the cooperating cells in the determined candidate CoMP cooperating set; the eNodeBs being of the cooperating cell and receiving the CoMP cooperating set establishment request responding to the CoMP cooperating set establishment request to the eNodeB of the serving cell of the UE, and sending a CoMP cooperating set establishment response to the eNodeB of the serving cell of the UE; the eNodeB of the serving cell of the UE determining a CoMP cooperating set of the UE according to information of the CoMP cooperating set establishment response; and according to a coordinated multi-point communication mode, sharing data information and service bearer information of the UE of the CoMP cooperating set. The present invention guarantees coordinated multi-point joint transmission/reception, decreases the overhead and complexity of the communication system and furthermore reduces the time delay in the information exchange.

摘要翻译： 公开了一种在协调多点通信中建立CoMP协作集的方法，所述方法包括以下步骤：触发并启动协调的多点通信过程; 根据由UE测量的测量小区集中的所有小区的信道状态信息，确定候选的CoMP协作组; 向确定的候选CoMP协作集中的协作小区的eNodeB发送CoMP协作组建立请求; 所述eNodeB是协作小区，并且将响应于所述CoMP协作组建立请求的所述CoMP协作组建立请求接收到所述UE的所述服务小区的eNodeB，并且向所述服务小区的eNodeB发送CoMP协作集合建立响应 UE; UE的服务小区的eNodeB根据CoMP合作组建立响应的信息确定UE的CoMP协作组; 并且根据协调的多点通信模式，共享CoMP协作组的UE的数据信息和业务承载信息。 本发明保证了协调的多点联合发送/接收，降低了通信系统的开销和复杂性，进而减少了信息交换中的时延。

公开(公告)号：US20120313390A1

公开(公告)日：2012-12-13

申请号：US13580035

申请日：2011-02-14

申请人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

发明人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

IPC分类号： B60R11/02 ,  H05K5/00

CPC分类号： B60R11/02 ,  B60K2350/00 ,  B60K2350/941 ,  B60K2350/945 ,  B60K2350/946 ,  B60K2350/948 ,  B60R2011/0047

摘要： A connecting device adapted for connecting a multifunctional box with a vehicle multimedia system may be provided. The connecting device may comprise a shell for holding the multifunctional box having a first open end portion and a second end portion configured with an interface, via which the multifunctional box is electrically connected with the vehicle multimedia system in a releasable manner; a locking unit formed on at least a lateral side between the first open portion and the second end portion for releasably locking the multifunctional box; and a release unit formed on the shell to release the inserted multifunctional box when pressed. A vehicle comprising the connecting device may also be provided.

摘要翻译： 可以提供适于将多功能盒与车载机多媒体系统连接的连接装置。 连接装置可以包括用于保持具有第一开口端部的多功能盒和配置有接口的第二端部的壳体，多功能盒通过该接口以可释放的方式与车辆多媒体系统电连接; 形成在所述第一开口部和所述第二端部之间的至少一侧的锁定单元，用于可释放地锁定所述多功能盒; 以及形成在外壳上的释放单元，以在按压时释放插入的多功能盒。 还可以提供包括连接装置的车辆。

公开(公告)号：US20110038277A1

公开(公告)日：2011-02-17

申请号：US12989893

申请日：2009-04-29

申请人： Zhenping Hu ,  Xiaodong Xu

发明人： Zhenping Hu ,  Xiaodong Xu

IPC分类号： H04L12/26 ,  H04L5/14

CPC分类号： H04L1/0027 ,  H04B17/309 ,  H04L1/0026

摘要： A method and equipment for determining the transmission resource of channel quality indicator are disclosed. They are applied in Time Division Duplex TDD system and Half Duplex-Frequency Division Duplex HD-FDD system when Discontinuous Reception DRX operation is adopted. The method includes the following steps: determining the location of the downlink subframe where the start point of monitoring Physical Downlink Control Channel PDCCH in DRX cycle is located; determining whether the transmission resource used for transmitting the Channel Quality Indicator CQI is an uplink subframe previous to the determined location or one or more uplink subframes after the determined location. Availability of the CQI information when performing downlink schedule is guaranteed, and the transmission resource used for transmitting CQI can be effectively saved.

摘要翻译： 公开了一种用于确定信道质量指示符的传输资源的方法和设备。 当采用不连续接收DRX操作时，它们应用于时分双工TDD系统和半双工 - 频分双工HD-FDD系统。 该方法包括以下步骤：确定DRX周期中监控物理下行链路控制信道PDCCH的起始点所在的下行子帧的位置; 确定用于发送信道质量指示符CQI的传输资源是否是所确定的位置之前的上行链路子帧，或者在确定的位置之后的一个或多个上行链路子帧。 确保执行下行链路调度时的CQI信息的可用性，能够有效地保存用于发送CQI的发送资源。

公开(公告)号：US09143972B2

公开(公告)日：2015-09-22

申请号：US13884368

申请日：2011-10-27

申请人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

发明人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

IPC分类号： H04W72/04 ,  H04W72/00 ,  H04W24/10 ,  H04B7/02 ,  H04B7/06 ,  H04W92/20

CPC分类号： H04W24/10 ,  H04B7/024 ,  H04B7/0626 ,  H04W72/0426 ,  H04W92/20

摘要： Disclosed is a method for establishing a CoMP cooperating set in coordinated multi-point communication, the method comprising the steps of: triggering and starting a coordinated multi-point communication process; according to channel state information of all cells in a measurement cell set measured by a UE, determining a candidate CoMP cooperating set; sending a CoMP cooperating set establishment request to eNodeBs of the cooperating cells in the determined candidate CoMP cooperating set; the eNodeBs being of the cooperating cell and receiving the CoMP cooperating set establishment request responding to the CoMP cooperating set establishment request to the eNodeB of the serving cell of the UE, and sending a CoMP cooperating set establishment response to the eNodeB of the serving cell of the UE; the eNodeB of the serving cell of the UE determining a CoMP cooperating set of the UE according to information of the CoMP cooperating set establishment response; and according to a coordinated multi-point communication mode, sharing data information and service bearer information of the UE of the CoMP cooperating set. The present invention guarantees coordinated multi-point joint transmission/reception, decreases the overhead and complexity of the communication system and furthermore reduces the time delay in the information exchange.

摘要翻译： 公开了一种在协调多点通信中建立CoMP协作集的方法，所述方法包括以下步骤：触发并启动协调的多点通信过程; 根据由UE测量的测量小区集中的所有小区的信道状态信息，确定候选的CoMP协作组; 向确定的候选CoMP协作集中的协作小区的eNodeB发送CoMP协作组建立请求; 所述eNodeB是协作小区，并且将响应于所述CoMP协作组建立请求的所述CoMP协作组建立请求接收到所述UE的所述服务小区的eNodeB，并且向所述服务小区的eNodeB发送CoMP协作集合建立响应 UE; UE的服务小区的eNodeB根据CoMP合作组建立响应的信息确定UE的CoMP协作组; 并且根据协调的多点通信模式，共享CoMP协作组的UE的数据信息和业务承载信息。 本发明保证了协调的多点联合发送/接收，降低了通信系统的开销和复杂性，进而减少了信息交换中的时延。

公开(公告)号：US20140155079A1

公开(公告)日：2014-06-05

申请号：US13907448

申请日：2013-05-31

申请人： Xiaodong Xu ,  Xiaofeng Tao ,  Zhou Xu ,  Huixin Zhang ,  Ping Zhang

发明人： Xiaodong Xu ,  Xiaofeng Tao ,  Zhou Xu ,  Huixin Zhang ,  Ping Zhang

IPC分类号： H04L5/00

CPC分类号： H04L5/0073 ,  H04L5/0037 ,  H04L5/0064 ,  H04L5/0067 ,  H04L5/0075

摘要： The present invention relates to the technical field of wireless communication and of mobile communication, and more particularly to a method for spectrum resource allocation and interference avoidance of femtocell in a heterogeneous environment consisting of macro cell and femtocell, and specifically to a spectrum allocation method based on interference suppression and user difference bandwidth requirements. According to the spectrum allocation method based on interference suppression and user difference bandwidth requirements of the present invention, spectrum resource can be allocated reasonably according to the priority level of bandwidth requirements in combination with graph coloring algorithm and chromaticity preference algorithm. In this manner, in-layer interference among femtocells and cross-layer interference among femtocells and macro cells can be effectively suppressed, the difference bandwidth requirements of femtocell users can be satisfied, and the efficiency of frequency utilization and the whole throughput of system can be also optimized to the maximum extent.

摘要翻译： 本发明涉及无线通信和移动通信的技术领域，更具体地涉及一种在由宏小区和毫微微小区组成的异构环境中的毫微微小区的频谱资源分配和干扰避免的方法，具体涉及基于频谱分配方法 对干扰抑制和用户差异带宽要求。 根据本发明的基于干扰抑制和用户差异带宽要求的频谱分配方法，可以根据带宽要求的优先级结合图像着色算法和色度偏好算法，合理分配频谱资源。 以这种方式，可以有效地抑制毫微微小区之间的层内干扰和毫微微小区和宏小区之间的跨层干扰，可以满足毫微微小区用户的差分带宽要求，并且可以使系统的频率利用效率和整体吞吐量 也在最大程度上进行了优化。