公开(公告)号：US20070244544A1

公开(公告)日：2007-10-18

申请号：US11279769

申请日：2006-04-14

申请人： Matthew Birdsall ,  Mark Dolan ,  Justin Goshgarian ,  Michael Krivoruchko ,  Joseph Lessar ,  Darrel Untereker ,  Peter Urbanski

发明人： Matthew Birdsall ,  Mark Dolan ,  Justin Goshgarian ,  Michael Krivoruchko ,  Joseph Lessar ,  Darrel Untereker ,  Peter Urbanski

IPC分类号： A61F2/24 ,  A61F2/06

CPC分类号： A61F2/2412 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2002/9528 ,  A61F2210/0061 ,  A61F2250/006 ,  A61F2250/0069 ,  A61L24/0031 ,  A61L24/08 ,  C08L5/08

摘要： A valve replacement system that can be used for treating abnormalities of the right ventricular outflow tract includes a prosthetic valve device having a sealant contacting at least a portion of the outer surface of the valve device. The sealant may be breakable, and may be a hydrogel, an expandable hydrogel, or a solid. One embodiment of the invention includes a flowable sealant that is injected within the vascular system. Another embodiment of the invention includes a method for replacing a pulmonary valve that includes forming a seal around the exterior surface of a replacement valve and preventing blood flow around the replacement valve.

摘要翻译： 可用于治疗右心室流出道异常的瓣膜置换系统包括具有与阀装置的外表面的至少一部分接触的密封剂的人造瓣膜装置。 密封剂可以是可破裂的，并且可以是水凝胶，可膨胀水凝胶或固体。 本发明的一个实施方案包括注射在血管系统内的可流动的密封剂。 本发明的另一个实施例包括一种用于替换肺动脉瓣的方法，该方法包括在置换瓣膜的外表面周围形成密封并防止置换瓣膜周围的血液流动。

公开(公告)号：US20080249599A1

公开(公告)日：2008-10-09

申请号：US11696816

申请日：2007-04-05

申请人： Jeffrey Allen ,  Scott Doig ,  Matthew J. Birdsall ,  Darrel Untereker

发明人： Jeffrey Allen ,  Scott Doig ,  Matthew J. Birdsall ,  Darrel Untereker

IPC分类号： A61F2/82

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91558 ,  A61F2250/0023 ,  A61F2250/0067

摘要： A system for treating abnormalities of the cardiovascular system includes a stent having a plurality of therapeutic agent-carrying regions and non therapeutic agent-carrying regions. The therapeutic agent-carrying regions are located within low strain regions of the stent and the non therapeutic agent-carrying regions are located within high strain regions of the stent. Another embodiment of the invention includes a method of manufacturing a therapeutic agent-carrying stent comprising forming a stent framework and applying a formulation containing one or more therapeutic agents to the stent framework while preventing the therapeutic agents from contacting the high strain regions of the stent framework.

摘要翻译： 用于治疗心血管系统异常的系统包括具有多个治疗剂携带区域和非治疗剂携带区域的支架。 治疗剂携带区域位于支架的低应变区域内，并且非治疗剂携带区域位于支架的高应变区域内。 本发明的另一个实施方案包括制备治疗剂携带支架的方法，包括形成支架框架并将含有一种或多种治疗剂的制剂施用于支架框架，同时防止治疗剂接触支架框架的高应变区域 。