公开(公告)号：US09060889B2

公开(公告)日：2015-06-23

申请号：US12693593

申请日：2010-01-26

申请人： Richard Bliss ,  Justin Goshgarian ,  Rui Lam ,  Padraig Savage ,  Erik Griswold ,  Gianfranco Pellegrini ,  Matthew Baldwin ,  Lance Ensign

发明人： Richard Bliss ,  Justin Goshgarian ,  Rui Lam ,  Padraig Savage ,  Erik Griswold ,  Gianfranco Pellegrini ,  Matthew Baldwin ,  Lance Ensign

IPC分类号： A61F2/06 ,  A61F2/88 ,  A61F2/915

CPC分类号： B21F45/008 ,  A61F2/88 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91558 ,  B21F1/04 ,  B21F3/02 ,  B23K31/027 ,  B23K2101/22 ,  B23K2201/22 ,  Y10T29/49826

摘要： A stent includes a continuous wave form having a plurality of struts and a plurality of crowns throughout the wave form. Each crown connects two adjacent struts. The wave form is wrapped around a longitudinal axis to define a central portion and two end portions located on opposite sides the central portion. The central portion includes a plurality of turns wrapped around the longitudinal axis and oriented at a first pitch angle relative to the longitudinal axis. The end portions each include a plurality of turns wrapped around the longitudinal axis and oriented at different pitch angles, and an end turn oriented at an angle relative to the longitudinal axis. The different pitch angles of the end portions are between the first pitch angle and the angle of the end turn relative to the longitudinal axis.

摘要翻译： 支架包括具有整个波浪形状的多个支柱和多个冠部的连续波形。 每个皇冠连接两个相邻的支柱。 波形围绕纵向轴线包围以限定位于中心部分的相对侧上的中心部分和两个端部部分。 中心部分包​​括围绕纵向轴线缠绕并相对于纵向轴线以第一俯仰角定向的多个匝。 端部分别包括围绕纵向轴线缠绕并以不同的俯仰角定向的多个匝和相对于纵向轴线成一定角度定向的端匝。 端部的不同桨距角位于第一桨距角和端匝相对于纵向轴线的角度之间。

公开(公告)号：US20120191175A1

公开(公告)日：2012-07-26

申请号：US13010599

申请日：2011-01-20

申请人： Michael Costa ,  Lance Ensign ,  John Richardson ,  Justin Goshgarian ,  Mark Hoff ,  Rui Lam ,  John Imschweiler

发明人： Michael Costa ,  Lance Ensign ,  John Richardson ,  Justin Goshgarian ,  Mark Hoff ,  Rui Lam ,  John Imschweiler

IPC分类号： A61F2/82 ,  B21F45/06

CPC分类号： B21F15/06 ,  A61F2/88 ,  A61F2/90 ,  A61F2002/91558 ,  A61F2002/91591 ,  A61F2220/0033 ,  A61F2250/0071 ,  B21F15/08 ,  B21F45/008

摘要： A tubular stent includes a plurality of bands aligned generally along a common longitudinal axis. A first band has a plurality of first crowns and a second band adjacent to the first band has a plurality of second crowns. A connecting ring connects the first band to the second band, wherein one of the first crowns is rotatably disposed through a lumen of the connecting ring and one of the second crowns is fused to the wall of the connecting ring outside of the lumen of the connecting ring. Methods of making tubular stents with rotatable connections are also disclosed.

摘要翻译： 管状支架包括大致沿着共同的纵向轴线排列的多个带。 第一带具有多个第一冠，并且与第一带相邻的第二带具有多个第二冠。 连接环将第一带连接到第二带，其中第一冠中的一个可旋转地设置穿过连接环的内腔，并且第二冠中的一个将熔接到连接环的壁在连接的内腔外部 环。 还公开了具有可旋转连接的管状支架的制造方法。

公开(公告)号：US20120143293A1

公开(公告)日：2012-06-07

申请号：US13281395

申请日：2011-10-25

申请人： Kevin Mauch ,  Mario Alvarado ,  Robert Beetel ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Sukyoung Shin ,  Michele Silver ,  Sina Som ,  Andrew Wu ,  Denise Zarins ,  Juanita Sanchez-Cole ,  Maria G. Aboytes

发明人： Kevin Mauch ,  Mario Alvarado ,  Robert Beetel ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Sukyoung Shin ,  Michele Silver ,  Sina Som ,  Andrew Wu ,  Denise Zarins ,  Juanita Sanchez-Cole ,  Maria G. Aboytes

IPC分类号： A61N1/18 ,  A61F7/12

CPC分类号： A61B18/1492 ,  A61B2018/00023 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61M25/0041 ,  A61M25/0074 ,  A61M25/0133 ,  A61M25/0138 ,  A61M25/0147

摘要： Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery or low-profile state (e.g., a generally straight shape) and a deployed state (e.g., a radially expanded, generally helical shape). The multi-electrode array is sized and shaped so that the electrodes or energy delivery elements contact an interior wall of the renal blood vessel when the array is in the deployed (e.g., helical) state. The electrodes or energy delivery elements are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function or of vascular structures that feed or perfuse the neural fibers.

公开(公告)号：US20120012014A1

公开(公告)日：2012-01-19

申请号：US12838778

申请日：2010-07-19

申请人： Justin Goshgarian ,  Erik Griswold

发明人： Justin Goshgarian ,  Erik Griswold

IPC分类号： B30B13/00

CPC分类号： B30B15/022 ,  B30B15/26

摘要： A method for forming a wave form for a stent. The wave form includes a plurality of substantially straight portions and a plurality of curved portions. Each curved portion connects adjacent substantially straight portions. The method includes feeding a formable material between a first die and a second die, the first die having a protruding surface in the shape of the wave form, and the second die having a recessed surface in the shape of the wave form complementing the protruding surface of the first die, pressing the formable material with the protruding surface of the first die into contact with the recessed surface of the second die, and shearing the wave form from the formable material with shearing forces created by the pressing.

摘要翻译： 一种形成支架波形的方法。 波形包括多个基本上直的部分和多个弯曲部分。 每个弯曲部分连接相邻的基本上直的部分。 该方法包括在第一模具和第二模具之间馈送可成形材料，第一模具具有波形形状的突出表面，并且第二模具具有与波形形状互补的凹形表面 的第一模具，用第一模具的突出表面挤压可成型材料与第二模具的凹入表面接触，并且通过由压制产生的剪切力剪切来自可成形材料的波形。

公开(公告)号：US20080319529A1

公开(公告)日：2008-12-25

申请号：US11935459

申请日：2007-11-06

申请人： Michael Krivoruchko ,  Matthew Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

发明人： Michael Krivoruchko ,  Matthew Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

IPC分类号： A61F2/06

CPC分类号： A61F2/88 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91558 ,  A61F2220/0058 ,  A61F2250/0036

摘要： A stent includes a central portion having a first waveform. The first waveform is wrapped around a longitudinal axis of the stent at a pitch to define a plurality of helical turns. The stent also includes an end segment connected to one end of the central portion. The end segment has a second waveform that includes a plurality of struts and a plurality of crowns. Each of the plurality of struts has a different length so that peaks of the crowns that define an end of the stent lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.

公开(公告)号：US20070168010A1

公开(公告)日：2007-07-19

申请号：US11275607

申请日：2006-01-19

申请人： Justin Goshgarian

发明人： Justin Goshgarian

IPC分类号： A61F2/06

CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91541 ,  A61F2002/9155

摘要： A stent delivery system is provided that comprises an inner member and an expandable balloon mounted on the inner member. A stent, which is mounted around at least a portion of the expandable balloon, comprises a plurality of alternating, hingedly-coupled crown sections and strut sections. Each adjacent crown section and strut section is coupled together via a hinge comprising a region having a thickness substantially less than that of the adjacent crown section and strut section.

摘要翻译： 提供了一种支架输送系统，其包括内部构件和安装在内部构件上的可膨胀气囊。 围绕可膨胀气囊的至少一部分安装的支架包括多个交替的，铰接的冠部和支柱部分。 每个相邻的冠部分和支柱部分通过铰链连接在一起，所述铰链包括具有基本上小于相邻的冠部分和支柱部分的厚度的区域的区域。

公开(公告)号：US20060036308A1

公开(公告)日：2006-02-16

申请号：US10917594

申请日：2004-08-12

申请人： Justin Goshgarian

发明人： Justin Goshgarian

IPC分类号： A61F2/06

CPC分类号： A61F2/86 ,  A61F2/90 ,  A61F2/91 ,  A61F2/95 ,  A61F2/958 ,  A61F2002/072 ,  A61F2002/828

摘要： The stent having an extruded covering of the present invention, and method of making the same, provides a stent 112 having stent elements 116 forming cells 118, and a covering 114 disposed on the stent 112. The seamless covering 114 encloses the stent elements 116 and the cells 118. The stent having an extruded covering is fabricated by compressing a stent assembly radially 252, applying molten polymer to the stent elements and cells 254, expanding the stent assembly radially to form a covering 252, and cooling the stent assembly 254. The stent assembly can then be separated into individual stents. The compression can be performed by drawing the stent assembly through a contracting die 154 and the molten polymer can be applied in an extruder 156. Before or after separating the stent assembly into individual stents, post treatment can be performed or coatings applied.

摘要翻译： 具有本发明的挤出覆盖物的支架及其制造方法提供了具有形成细胞118的支架元件116的支架112和设置在支架112上的覆盖物114。 无缝覆盖物114包围支架元件116和电池118。 具有挤出覆盖物的支架通过径向252压缩支架组件来制造，将熔融聚合物施加到支架元件和细胞254，径向膨胀支架组件以形成覆盖件252，并冷却支架组件254。 然后将支架组件分离成单独的支架。 可以通过拉伸支架组件通过收缩模具154来进行压缩，并且可以将熔融聚合物施加在挤出机156中。 在将支架组件分离成各个支架之前或之后，可以执行后处理或施加涂层。

公开(公告)号：US20050154447A1

公开(公告)日：2005-07-14

申请号：US10753461

申请日：2004-01-09

申请人： Justin Goshgarian

发明人： Justin Goshgarian

IPC分类号： A61B17/11 ,  A61F2/82 ,  A61F2/86 ,  A61F2/90 ,  A61F2/06

CPC分类号： A61F2/90 ,  A61F2/848 ,  A61F2/86 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/821 ,  A61F2220/0058 ,  A61F2230/005 ,  A61F2230/0054 ,  A61F2230/0078

摘要： An ostium stent system includes a stent having a tubular body at the distal portion of the stent and a flaring portion at the proximal portion of the stent. A restraining structure that deploys the flaring portion covers only the proximal portion of the stent, providing a low profile for smooth delivery of the stent to the treatment site. The flaring portion comprises at least one flaring member which each comprise a short segment and a long segment. In an unexpanded configuration, each short and long segment are parallel to a longitudinal axis of the tubular body. When the flaring portion is deployed, each short segment remains parallel while each long segment becomes perpendicular to the longitudinal axis of the tubular body. The short segments therefore absorb the radial force resulting from deployment of the long segments and thereby prevent the stent from lifting off the balloon.

摘要翻译： 口支架系统包括支架，其在支架的远端部分具有管状体，在支架的近端部分具有扩口部。 展开扩口部分的限制结构仅覆盖支架的近端部分，提供了将支架平滑地输送到治疗部位的低轮廓。 扩口部分包括至少一个扩口构件，每个扩口构件包括短段和长段。 在未膨胀的构造中，每个短段和长段平行于管状体的纵向轴线。 当扩口部分展开时，每个短节段保持平行，而每个长节段变得垂直于管状体的纵向轴线。 因此，短段因此吸收由长部段展开而产生的径向力，从而防止支架从气囊上脱落。

公开(公告)号：US20120116383A1

公开(公告)日：2012-05-10

申请号：US13281361

申请日：2011-10-25

申请人： Kevin Mauch ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Martin Rothman

发明人： Kevin Mauch ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Martin Rothman

IPC分类号： A61B18/18

CPC分类号： A61B18/1492 ,  A61B2018/00023 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61M25/0041 ,  A61M25/0074 ,  A61M25/0133 ,  A61M25/0138 ,  A61M25/0147

摘要： Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery or low-profile state (e.g., a generally straight shape) and a deployed state (e.g., a radially expanded, generally helical shape). The multi-electrode array is sized and shaped so that the electrodes or energy delivery elements contact an interior wall of the renal blood vessel when the array is in the deployed (e.g., helical) state. The electrodes or energy delivery elements are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function or of vascular structures that feed or perfuse the neural fibers.

摘要翻译： 本文公开了通过血管内通路实现肾脏神经调节的导管装置，系统和方法。 例如，本技术的一个方面涉及具有被配置为输送到肾血管的多电极阵列的治疗装置。 阵列可以在传送或低轮廓状态（例如，大致直线形状）和展开状态（例如，径向膨胀，大致螺旋形状）之间选择性地变换。 多电极阵列的尺寸和形状使得当阵列处于部署（例如螺旋状态）时，电极或能量递送元件接触肾血管的内壁。 电极或能量输送元件构造成用于直接和/或间接施加热和/或电能以加热或以其他方式电调节有助于肾功能的神经纤维或者供给或灌注神经纤维的血管结构。

公开(公告)号：US20110071620A1

公开(公告)日：2011-03-24

申请号：US12693593

申请日：2010-01-26

申请人： Richard Bliss ,  Justin Goshgarian ,  Rui Lam ,  Padraig Savage ,  Erik Griswold ,  Gianfranco Pellegrini ,  Matthew Baldwin ,  Lance Ensign

发明人： Richard Bliss ,  Justin Goshgarian ,  Rui Lam ,  Padraig Savage ,  Erik Griswold ,  Gianfranco Pellegrini ,  Matthew Baldwin ,  Lance Ensign

IPC分类号： A61F2/82 ,  B23P11/00

CPC分类号： B21F45/008 ,  A61F2/88 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91525 ,  A61F2002/91558 ,  B21F1/04 ,  B21F3/02 ,  B23K31/027 ,  B23K2101/22 ,  B23K2201/22 ,  Y10T29/49826

摘要： A method of manufacturing a stent includes forming a wave form having a plurality of struts and a plurality of crowns. Each crown connects two adjacent struts. The wave form has a central portion and two end portions located on opposite sides the central portion. Some of the struts located in the end portions have lengths longer and/or shorter than an average length of all of the struts of the wave form. The method includes wrapping the wave form about a longitudinal axis to define a plurality of turns so that an end turn is oriented at an angle relative to the longitudinal axis, a second turn is at a first pitch angle that is less than the angle that the end turn is disposed relative to the longitudinal axis, a third turn is at a second pitch angle that is less than the first pitch angle, and a fourth turn is at a third pitch angle that is less than the second pitch angle.

摘要翻译： 制造支架的方法包括形成具有多个支柱和多个牙冠的波形。 每个皇冠连接两个相邻的支柱。 波形具有位于中心部分的相对侧上的中心部分和两个端部部分。 位于端部中的一些支柱具有比波形的所有支柱的平均长度更长和/或更短的长度。 该方法包括围绕纵向轴线缠绕波形以限定多个匝，使得端部匝相对于纵向轴线成一定角度，第二匝处于第一倾斜角度，其小于 端部匝相对于纵向轴线设置，第三匝处于小于第一俯仰角的第二俯仰角，并且第四匝处于小于第二俯仰角的第三俯仰角。