Correction method for quantification accuracy improvement in list mode reconstruction

    公开(公告)号:US11428829B2

    公开(公告)日:2022-08-30

    申请号:US16963320

    申请日:2019-01-30

    Abstract: A non-transitory computer-readable medium stores instructions readable and executable by a workstation (18) including at least one electronic processor (20) to perform an image reconstruction method (100) to reconstruct list mode data acquired over a frame acquisition time using a plurality of radiation detectors (17) in which the events of the list mode data is timestamped. The method includes: for the sub-frame bins of a plurality of sub-frame bins into which the frame acquisition time is divided, determining a sub-frame singles rates map for the plurality of radiation detectors from the list mode data whose time stamps reside in the sub-frame bin; determining a singles rate for the singles events of the list mode data using the sub-frame singles rates maps wherein the singles rates for the singles events are determined at a temporal resolution that is finer than the frame acquisition time; determining correction factors for the list mode data using the determined singles rates for the singles events of the list mode data; and reconstructing the list mode data of the frame acquisition time using the determined correction factors to generate a reconstructed image for the frame acquisition time.

    Iterative image reconstruction with dynamic suppression of formation of noise-induced artifacts

    公开(公告)号:US11210820B2

    公开(公告)日:2021-12-28

    申请号:US16336562

    申请日:2017-09-25

    Abstract: Iterative reconstruction (20) of imaging data is performed to generate a sequence of update images (22) terminating at a reconstructed image. During the iterative reconstruction, at least one of an update image and a parameter of the iterative reconstruction is adjusted using an adjustment process separate from the iterative reconstruction. In some embodiments using an edge-preserving regularization prior (26), the adjustment process (30) adjusts an edge preservation threshold to reduce gradient steepness above which edge preservation applies for later iterations compared with earlier iterations. In some embodiments, the adjustment process includes determining (36, 38) for each pixel, voxel, or region of a current update image whether its evolution prior to the current update image 22) satisfies an artifact feature criterion. A local noise suppression operation (40) is performed on the pixel, voxel, or region if the evolution satisfies the artifact feature criterion and is not performed otherwise.

    Solving outside-field of view scatter correction problem in positron emission tomography via digital experimentation

    公开(公告)号:US10036817B2

    公开(公告)日:2018-07-31

    申请号:US15569209

    申请日:2016-04-25

    CPC classification number: G01T1/2985 G01T1/2992

    Abstract: Method and apparatus are disclosed for generating a scatter-corrected image from positron emission tomography (PET) or other radioemission imaging data (20) acquired of an object (12) in a field of view (14). A background portion (26B) of the PET imaging data is identified corresponding to a background region (14B) of the FOV that is outside of the object. An outside-FOV activity estimate (40) for at least one spatial region outside of the FOV and into which the object extends is adjusted (e.g. iterative or several randomly selected estimates) to optimize a simulated scatter distribution for the combination of the PET imaging data and the outside FOV activity estimate to match the background portion (26B) of the PET imaging data. The PET imaging data are reconstructed to generate a scatter-corrected PET image of the object in the FOV using the optimized simulated scatter distribution.

    Standardized uptake value (SUV) guided reconstruction control for improved outcome robustness in positron emission tomography (PET) imaging

    公开(公告)号:US11158094B2

    公开(公告)日:2021-10-26

    申请号:US16474576

    申请日:2018-01-03

    Abstract: A nuclear medicine image reconstruction method generates a reconstructed image (44) by performing iterative image in reconstruction (30, 130) on nuclear medicine imaging data (22). The iterative image reconstruction produces a sequence of update images (34, 36, 134, 136). During the iterative image reconstruction, a standardized uptake value (SUV) transform (40) is applied to convert an update image (34, 36) to an update SUV image (42, 46). The SUV transform scales values of voxels of the update image to SUV values using scaling factors including at least a body size metric and a dose metric. During the iterative image reconstruction, at least one parameter used in an image update of the iterative image reconstruction is adjusted using the update SUV image. For example, a parameter of a prior or filter (38) incorporated into an image reconstruction update step (32) or used in filtering of an update image (36) may be adjusted.

    Feature-based image processing using feature images extracted from different iterations

    公开(公告)号:US11049230B2

    公开(公告)日:2021-06-29

    申请号:US16325213

    申请日:2017-08-22

    Abstract: Image processing performed by a computer (22) includes iterative image reconstruction or refinement (26, 56) that produces a series of update images ending in an iteratively reconstructed or refined image. A difference image (34, 64) is computed between a first update image (30, 60) and a second update image (32, 62) of the series. The difference image is converted to a feature image (40) and is used in the iterative processing (26, 56) or in post-processing (44) performed on the iteratively reconstructed or refined images or images from different reconstruction or refinement techniques. In another embodiment, first and second image reconstructions (81, 83) are performed to generate respective first and second reconstructed images (80, 82). A difference image (84) is computed between two images each selected from the group: the first reconstructed image, an update image of the first reconstruction, the second reconstructed image, and an update image of the second reconstruction. A feature image is generated from the difference image and used to combine the first and second reconstructed images.

    Time-of-flight resolution-adaptive image regularization and filtering in positron emission tomography

    公开(公告)号:US11009615B2

    公开(公告)日:2021-05-18

    申请号:US16470730

    申请日:2017-12-18

    Abstract: A time of flight (TOF) positron emission tomography (PET) image (38) is generated from TOF PET imaging data (10) acquired of a subject using a TOF PET imaging data acquisition device (6). Iterative image reconstruction (30) of the TOF PET imaging data is performed with TOF localization of counts along respective lines of response (LORs) to iteratively update a reconstructed image (32). Values for at least one regularization or filtering parameter are assigned to the TOF PET imaging data or to voxels of the reconstructed image based on an estimated TOF localization resolution for the TOF PET imaging data or voxels. Regularization (34) or filtering (36) of the reconstructed image is performed using the assigned values for the at least one regularization or filtering parameter. In some embodiments, the varying TOF localization resolution for the TOF PET imaging data or voxels is estimated based on related acquisition characteristics such as count rates or operating temperature of the detectors.

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