公开(公告)号：US20160279156A1

公开(公告)日：2016-09-29

申请号：US14776826

申请日：2014-03-11

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Nam Joo Kang ,  Kyoung Heon Kim ,  In-Geol Choi ,  Young Ah Kim ,  Eun-Ju Yun ,  Sae Young Lee

IPC: A61K31/7004

CPC classification number: A61K31/7004 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/308 ,  A23V2250/60 ,  A23V2250/608

Abstract: The present invention relates to a composition for preventing or treating colon cancer, containing 3,6-anhydro-L-galactose, and more specifically, provides excellent anti-cancer effects by inducing apoptosis of colon cancer cells and inhibiting the growth of colon cancer cells by using 3,6-anhydro-L-galactose separated from red algae-derived agar and purified.

Abstract translation: 本发明涉及含有3,6-脱水-L-半乳糖的预防或治疗结肠癌的组合物，更具体地说，通过诱导结肠癌细胞的凋亡和抑制结肠癌细胞的生长来提供优异的抗癌作用 通过使用从红藻衍生的琼脂分离的3,6-脱水-L-半乳糖并纯化。

公开(公告)号：US20160265012A1

公开(公告)日：2016-09-15

申请号：US15029160

申请日：2014-10-08

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Kyoung Heon Kim ,  In-Geol Choi ,  Chan Hyoung Lee ,  Hee Taek Kim ,  Eun-Ju Yun

IPC: C12P19/14 ,  C12N9/40 ,  C12P19/02 ,  C12N9/38

CPC classification number: C12P19/14 ,  C12N9/2465 ,  C12N9/2468 ,  C12P19/02 ,  C12Y302/01 ,  C12Y302/01081 ,  C12Y302/01082 ,  C12Y302/01159

Abstract: The present invention relates to agarooligosaccharide hydrolase and a method for producing 3,6-anhydro-L-galactose and galactose from agarose by using the same. More specifically, the production yield of 3,6-anhydro-L-galactose and galactose from agarose, that is, the saccharification yield, is improved by using β-agarooligosaccharide hydrolase having an agarotriose hydrolytic activity.

Abstract translation: 本发明涉及琼脂糖水解酶和通过使用它们从琼脂糖生产3,6-脱水-L-半乳糖和半乳糖的方法。 更具体地说，通过使用具有抗坏血酸水解活性的β-琼脂寡糖水解酶，可以提高来自琼脂糖的3,6-脱水-L-半乳糖和半乳糖的产率，即糖化收率。

公开(公告)号：US20160097043A1

公开(公告)日：2016-04-07

申请号：US14786711

申请日：2014-04-25

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Kyoung Heon Kim ,  In-Geol Choi ,  Hee Jin Lee ,  In Jung Kim

IPC: C12N9/42 ,  C12P19/02 ,  C12P19/14

CPC classification number: C12N9/2437 ,  C12P19/02 ,  C12P19/14 ,  C12Y302/01004

Abstract: The present invention provides Hahella chejuensis-derived recombinant cellulase and a use thereof. The recombinant cellulase according to the present invention has a high stability at a high temperature and an optimized activity at a neutral pH, and therefore has a high availability in a process. Also, since the cellulase according to the present invention has an exoglucanase activity as well as an endoglucanase activity, a monosaccharide can be produced during decomposition of cellulose and an additional treatment required in a fermentation process is not needed, and therefore a cost may be reduced. Such an enzyme activity is advantageous to a fermentation or thermal treatment condition for producing a biofuel, and therefore industrial profits may be achieved.

Abstract translation: 本发明提供了来源于哈氏藻的重组纤维素酶及其用途。 根据本发明的重组纤维素酶在高温下具有高稳定性和在中性pH下具有优化的活性，因此在该方法中具有高可用性。 此外，由于本发明的纤维素酶具有外切葡聚糖酶活性以及内切葡聚糖酶活性，所以在纤维素分解过程中可以制造单糖，不需要发酵工序所需的附加处理，因此成本降低 。 这样的酶活性对于生产生物燃料的发酵或热处理条件是有利的，因此可以实现工业利润。