摘要:
A substantially continuous image, recording motion of a portion of a sample, is provided by first NMR exciting, through use of a rotating-gradient (.rho.) pulse signal, a relatively narrow cylindrical region, typically with diameter less than 1 inch, of magnetization intersecting the sample to be imaged and then acquiring the NMR response signal thus excited, in the presence of a readout gradient oriented along the length of the cylindrical excitation beam and establishing position thereon. A Fourier transformation of the acquired data allows display of a real-time record of the profile of the sample along the axis of the cylindrical probe beam. The cylinder-beam axis can be oriented in an arbitrary direction by proper mixing of the excitation and readout gradient fields; use of three orthogonal gradients in a Cartesian coordinate system is presently preferred. Spatial offsetting of the cylindrical beam, from the center of the static magnetic field of the NMR imaging system, to any specific location within the system's imaging volume, can be obtained by frequency modulation of the .rho. pulse RF waveform.
摘要:
Imaging parameters, such as the location, orientation and field of view of an imaging plane are selected. These parameters are provided to a pulse sequencer of a magnetic resonance (MR) scanner which modifies an MR pulse sequence to acquire an image at the selected imaging plane. The pulse sequencer controls an RF transmitter and gradient amplifiers to cause an MR image of the subject at an imaging plane to be acquired. The MR image is displayed on a display device. An interface device receives and reduces the MR image to an image icon and saves the image icon along with the corresponding imaging parameters. The image icons are displayed on the periphery of the screen around an MR image. An operator may then view and select one of the image icons, employing the pointing device. This causes the imaging parameters corresponding to the selected image icon to be sent to the pulse sequencer thereby causing an MR image to be acquired with these imaging parameters.
摘要:
Surgery is performed with a pulsed heat-producing device that selectively heats a region in a specific tissue within a patient destroying the tissue. The pulsed heat-producing device may be a coherent optical source that is guided by laser fiber to the tissue to be destroyed. In another embodiment, the pulsed heat-producing device is a focussed ultrasound transducer which concentrates ultrasonic energy at a focal point within the specific tissue. A magnetic resonance imaging system employing a real-time temperature-sensitive pulse sequence monitors the heated region of the tissue to provide temperature profiles allowing an operator to alter the position and size of the heated region.
摘要:
A method for reducing distortion in magnetic resonance (MR) images of a subject employs distortion compensating MR pulses in a conventional MR imaging sequence. The distortion compensating pulses are determined by first creating a conventional MR image of a slice of a subject having inherent distortions; constructing a target slice which is distorted in a manner opposite the direction of distortions in the slice image; taking a multi-dimensional Fourier transformation of the target slice to obtain a k-space region; choosing a continuous trajectory which efficiently traverses the k-space region; applying principles of multidimensional selective-excitation design to create simultaneous RF pulses and magnetic field gradient waveforms from the trajectory; and simultaneously applying the RF pulses and gradient waveforms in place of a traditional slice-select pulse in conventional MR imaging sequences to obtain images having reduced distortion as compared with conventional images.
摘要:
A method for providing information about the rate of a selected chemical reaction in each of at least one selected volume elements (voxels) in a sample includes the steps of: exciting a reaction-rate-dependent chemical-shift spectrum, by a selected stimulus (such as one of saturation-transfer and inversion-transfer RF signal pulses) to label the NMR signal of a first reaction constituent; spatially localizing the NMR response signal, provided by the excited resonance, to a selected voxel within the sample; and acquiring and processing the NMR response data from the localized voxel. The excitation, localization and data acquisition subsequences are repeated to generate data substantially proportional, or equal, to the reaction rate constants in the selected voxels, and in planes and/or volumes thereof.
摘要:
A method of imaging and quantitatively measuring blood velocity distribution within a selected vessel employs Nuclear Magnetic Resonance cylindrical excitation of the sample to be imaged, followed by Fourier velocity encoding excitation along a second axis for selectively encoding molecules based upon their flow velocities, then sensing the re-radiated signal data acquired in the presence of a readout gradient to provide resolution along the cylindrical axis, and reconstructing a velocity profile. Spatial localization is accomplished with an excitation pulse having a cylindrical rather than slab geometry. This method can be combined with cardiac synchronization to measure flow dynamics or it can be applied without synchronization to measure steady flow. The geometry of the measurement is flexible in that the directions of flow sensitivity and geometric resolution are independent.
摘要:
A single rotating NMR .pi. pulse provides simultaneous spatially-selective inversion or spin-echo refocussing of nuclear pins in two orthogonal dimensions. The two-dimensional spatially-selective pulse utilizes a single RF pulse, with either a square of an amplitude-modulated or a frequency-modulated envelope, and applied in the presence of an amplitude-modulated magnetic field gradient which reorients through the desired dimensions in which selection is desired while the RF pulse is present. These rotating, or ".rho.", pulses are useful for reduction of aliasing signal artifacts is restricted field-of-view high-resolution NMR imaging and, when combined with one-dimensional-localized chemical shift spectroscpoy techniques (such as those employing surface detection coils) is especially useful for the production of three-dimensionally localized NMR spectra. Substantial suppression of undesirable residual excited signals, arising from outside the desired two-dimensional spatially selected region, can be obtained by simulated annealing optimization of both the RF and magnetic field gradient amplitude portions of the .rho. pulse and/or by use of surface coil detection. The location of the selected volume is varied by frequency modulation of the RF signal pulse, or by variation of the ratio of currents in the halves of the magnetic field gradient coils.
摘要:
A multi-planar imaging method employs magnetic resonance to detect image data from multiple planes within a subject. Data from each plane are detected in response to the same readout gradient and are simultaneously detected. The image planes can be arbitrarily oriented with respect to each other and with respect to the readout and phase-encoding image formation magnetic field gradient pulses if desired. Overlap of image data from each of the excited image planes in the acquired image is prevented by modulating the phase of each RF excitation pulse in concert with the amplitude of the phase-encoding gradient pulse to cause the image data from each excitation plane to be displaced by a unique amount in the phase-encoding direction.
摘要:
Three-dimensional (3D) image data is acquired from a subject with a medical imaging device and stored. The stored 3D image data is processed by a model workstation to segment the model into discrete structures and produce a segmented computer graphic model. An operator interacts with the model workstation to cause it to display desired structures of the the segmented model in a desired view and orientation. The operator also selects a position and orientation of a cutting plane passing through the segmented model. Once selected, the position and orientation information is provided to a pulse sequencer of a magnetic resonance (MR) imaging system. The pulse sequencer controls an RF transmitter and gradient amplifiers to cause an MR image of the subject at an imaging plane, corresponding to the cutting plane of the model workstation, to be acquired. This allows fast, accurate image plane selection, which may be selected by an operator who is simultaneously performing a medical procedure on the subject, aid in the procedure.
摘要:
An MR image of a subject is displayed on a display device. Scan-control icons are displayed over this image. An operator interacts with an interface device to select imaging plane parameters during imaging. This is performed by selecting one of the icons with a pointing device, and dragging. Interface device then provides a display which indicates the motion of the imaging plane as well as the extent of the motion. Once selected, the location and orientation information transformed to global coordinates and is provided to a pulse sequencer of a magnetic resonance (MR) imaging system. The pulse sequencer controls an RF transmitter and gradient amplifiers to cause an MR image of the subject at an imaging plane to be acquired. This allows fast, accurate imaging plane selection, which may be selected by an operator who is searching for structures within the subject, or who is simultaneously performing a medical procedure on the subject.